ID A0A022M7Q3_9ACTN Unreviewed; 732 AA.
AC A0A022M7Q3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Elongation factor G {ECO:0000313|EMBL:EYT78506.1};
GN ORFNames=CF54_36725 {ECO:0000313|EMBL:EYT78506.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT78506.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT78506.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT78506.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT78506.1}.
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DR EMBL; JFJQ01001153; EYT78506.1; -; Genomic_DNA.
DR RefSeq; WP_037896561.1; NZ_KK106995.1.
DR AlphaFoldDB; A0A022M7Q3; -.
DR HOGENOM; CLU_002794_4_1_11; -.
DR OrthoDB; 9801472at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
DR CDD; cd04170; EF-G_bact; 1.
DR CDD; cd16262; EFG_III; 1.
DR CDD; cd01434; EFG_mtEFG1_IV; 1.
DR CDD; cd03713; EFG_mtEFG_C; 1.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.70.240; -; 1.
DR Gene3D; 3.30.70.870; Elongation Factor G (Translational Gtpase), domain 3; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR041095; EFG_II.
DR InterPro; IPR009022; EFG_III.
DR InterPro; IPR035647; EFG_III/V.
DR InterPro; IPR047872; EFG_IV.
DR InterPro; IPR035649; EFG_V.
DR InterPro; IPR000640; EFG_V-like.
DR InterPro; IPR004161; EFTu-like_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR005517; Transl_elong_EFG/EF2_IV.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR43261:SF6; ELONGATION FACTOR G-LIKE PROTEIN; 1.
DR PANTHER; PTHR43261; TRANSLATION ELONGATION FACTOR G-RELATED; 1.
DR Pfam; PF00679; EFG_C; 1.
DR Pfam; PF14492; EFG_III; 1.
DR Pfam; PF03764; EFG_IV; 1.
DR Pfam; PF00009; GTP_EFTU; 1.
DR Pfam; PF03144; GTP_EFTU_D2; 1.
DR PRINTS; PR00315; ELONGATNFCT.
DR SMART; SM00838; EFG_C; 1.
DR SMART; SM00889; EFG_IV; 1.
DR SUPFAM; SSF54980; EF-G C-terminal domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS51722; G_TR_2; 1.
PE 4: Predicted;
KW Elongation factor {ECO:0000313|EMBL:EYT78506.1};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Protein biosynthesis {ECO:0000313|EMBL:EYT78506.1}.
FT DOMAIN 22..310
FT /note="Tr-type G"
FT /evidence="ECO:0000259|PROSITE:PS51722"
FT REGION 311..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 732 AA; 78156 MW; DFB273E4C23C0756 CRC64;
MGDKAHTHPG AAGRAMAADH PASLRNVVLV GHSGSGKTTL VEALALTAGA VNRAGRVEDG
GCVSDYDEIE HRQQRSVQLS LVPVAWDGIK INLLDTPGYA DFVGELRAGL RAADAALFVV
SASDGVDGST RMVWEECAAV GMPRAIVITH LEAARADFEE MTRVCAEAFG ADDPDAVLPL
YLPLHGPEGP DGHAPVTGLV GLLTRKLFDY ASGERKESEP GADELPRMDE ARGRLIEGII
AESEDETLMD RYLGGEQVDV ETLIKDLERA VARGAFFPVL AAAPAADGAR QGIGTVELLD
LIVRGFPTPL EHEAPEVTTP DGRSRRPAPC APDGPLVAEV VKTASDPYVG RVSLVRVFSG
TLRPDETVHV SGHGLADRGH EDHDVDERIG ALSTPFGKQQ RPVTHAVAGD LVSVAKLNRA
ETGDTLSAKD DPLLMAPWQM PDPLLPLAIQ AHSKADEDKL SQGLARLVAE DPTMRLEQNQ
DTHQVVLWCL GEAHADVALE RLRSRYGVQV DVVPHRVSLR ETFAGRSAGR GRHVKQSGGH
GQYAICEIEV EPLPGGSGIE FVDKVVGGAV PRQFIPSVEK GVRAQAAKGV AAGHPLIDVR
VTLLDGKAHS VDSSDAAFQT AGALALREAA ADARIHLLEP VAEVSVLVGD DYVGAVMSDL
SGRRGRVLGT EQISGGRTLV RAEVPEIEIG RYAIDLRSLS HGTARFERRY ARHEPMPEQI
ADRLRQQERE AS
//
