ID A0A022MAL2_9ACTN Unreviewed; 313 AA.
AC A0A022MAL2;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Alcohol dehydrogenase {ECO:0000313|EMBL:EYT78373.1};
GN ORFNames=CF54_37585 {ECO:0000313|EMBL:EYT78373.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT78373.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT78373.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT78373.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT78373.1}.
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DR EMBL; JFJQ01001176; EYT78373.1; -; Genomic_DNA.
DR RefSeq; WP_037896650.1; NZ_KK106995.1.
DR AlphaFoldDB; A0A022MAL2; -.
DR HOGENOM; CLU_026673_3_3_11; -.
DR OrthoDB; 3727682at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd05289; MDR_like_2; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR44013; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR PANTHER; PTHR44013:SF1; ZINC-TYPE ALCOHOL DEHYDROGENASE-LIKE PROTEIN C16A3.02C; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
FT DOMAIN 10..305
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 313 AA; 33031 MW; 6D9887517C171C9B CRC64;
MKGISYRRYG GPEVLEYGDV RDPKVGPDSV LVEVRAAAVN PVDWKCREGY LDALLDPVFP
VVPGWDLAGV VVRPGAAVTE FSAGDEVIGY VREDFLSRGT FAEYVAAPVR TLARKPRGLS
FAEAAGIPLA GLTAHQVLTG ALRVGRGETV LVHAAAGGVG SFAVQLAAHL GARVIGTASE
RNHAYVRSLG GEPVSYGEGL AERVRGLAPE GVAAVFDTIG GETTRISAQL LAPEGRLASI
ADPEVTDYGG RYCFVRPDAR DLLHLSELAE QGVLSVHVAQ TYPLARAADA LRHSQEGRTR
GKIVVTVDRE TAA
//
