ID A0A022MIA7_9ACTN Unreviewed; 1325 AA.
AC A0A022MIA7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Cell division protein FtsK {ECO:0000313|EMBL:EYT81068.1};
GN ORFNames=CF54_21680 {ECO:0000313|EMBL:EYT81068.1};
OS Streptomyces sp. Tu 6176.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1470557 {ECO:0000313|EMBL:EYT81068.1, ECO:0000313|Proteomes:UP000020060};
RN [1] {ECO:0000313|EMBL:EYT81068.1, ECO:0000313|Proteomes:UP000020060}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Tu 6176 {ECO:0000313|EMBL:EYT81068.1,
RC ECO:0000313|Proteomes:UP000020060};
RA Olano C., Cano-Prieto C., Mendez C., Salas J.A.;
RT "Draft genome sequence of Streptomyces sp. Tu 6176, producer of the
RT cytotoxic benzoxazol nataxazol.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYT81068.1}.
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DR EMBL; JFJQ01000683; EYT81068.1; -; Genomic_DNA.
DR RefSeq; WP_037893039.1; NZ_KK106990.1.
DR HOGENOM; CLU_003134_1_0_11; -.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000020060; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR PROSITE; PS50901; FTSK; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Cell cycle {ECO:0000313|EMBL:EYT81068.1};
KW Cell division {ECO:0000313|EMBL:EYT81068.1};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 466..667
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 820..1011
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1106..1291
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 97..124
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 489..496
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 838..845
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1124..1131
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1325 AA; 143250 MW; B898325827899B8A CRC64;
MSTRLIHRPA RTTRPAAAPE PRTIEAPPNL PEGKAGSIAT SLLPVAGVMS SVVMMTVVRN
SQFAGLGAII LVVTLAGSMT LVFSQRGKAQ RTRRTQREAY LAYLEDLREE LSGEERERRE
RAQVLNPPPD ALYDIVRDPA RLWERRRVDG DFLRVRVGTG EMPVRDLKVA QQGSSVLTPP
DQFMLNEASA LMSRFSSGTE LPLTVPLDRV GNISVIGPRE DTLRVARALM VQTAATHAPD
DVAMALAAPG DRIADWEWAK WLPHLLDPEQ FDGPVAARRI APSLPQLARQ TGAELRRRAS
YAAEVRRGLS GPDALAMTSR LLVVADGHGA DAVELPRPDD AVGLREMGVT VLHLLDERVQ
EPGSVGVRIT VDGDRILIED LREAEPVSAH GTVDEVGVPF AEGLARMLAP LRLSAESMAD
APLTGPVDFA ELLGIDDVAR LDLDRLWAPR GERAFLRVPI GVSDAHEPVL LDLKESSELG
MGPHGLCVGA TGSGKSELLR TLVLALVATH PPDDLALVLV DYKGGATFAP FADLPHVAGV
ITNLENQAGL VERVHASLAG EVKRRQQVLK DAGNVADIGH YAALRAEKRP DLEPLPHLFV
VIDEFGELLT AKPDFIDLFL SIGRIGRSIG VHLLLSSQRI EGGKLKGLDT YLSYRLGLRT
FSADESRTVL DTTDAFHLPP LPGFGYLKVD TSHYERFKAS YVSGAYRGPV ERETEDTGPL
ALEYAAYNTL GQDGSTGAEE PQMRRRETGP TEMGVLVQQI EDAGARTVRR IWLPPLPDAI
ALDQVAGPVE VGARGMQLAG RRGPLRVPLG LLDDPTKQWQ GQWYLDLTVA GGHAAVIGGP
QSGKTTLLRT LALSLALTHT PQEVGVYGLD LVGGGLQALA GLPHVGGVAG RADRERAART
IDSVRGMLDQ REELFRVHNI DSLEQLRTLR AAGRLPELAS TEIVLLIDGF GALRDDFEDL
DDAVVDILKR GSGYGIHVVA GMLRWNDVRI ATQSQFGTRV ELRLNDPTES SVDRKLAETL
SPEEKGRVLT DGKLFAQVAL PRTDGLGDRA ELGAVLERTA RTVRATWTGE VAQPVRVLPH
LLEPHLLPGP AAEPRRVPIG LDQTKLAPVP LDLFAHDQHL MIMGDSECGK TNLLKVVVEG
LIERHGDDEL VFGVFDPRRG LRGAVPEEYR GGYAYNAKLA GALAHGIAGE LDKRLPDESA
DPADLEPGSW GSGPRIVILV DDYDVLTTAG QQPLAPFVPY IPSAVDIGLH FVLTRRVAGA
SRGLYEPLLQ GLRESGSTAL VMSGDRSEGQ LFPGVYASQQ PPGRGVLVRR GEPNRLIQTV
YAGNR
//
