ID A0A022PZI3_ERYGU Unreviewed; 445 AA.
AC A0A022PZI3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Magnesium transporter {ECO:0000256|RuleBase:RU366041};
GN ORFNames=MIMGU_mgv1a006408mg {ECO:0000313|EMBL:EYU21742.1};
OS Erythranthe guttata (Yellow monkey flower) (Mimulus guttatus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Lamiales; Phrymaceae; Erythranthe.
OX NCBI_TaxID=4155 {ECO:0000313|EMBL:EYU21742.1, ECO:0000313|Proteomes:UP000030748};
RN [1] {ECO:0000313|EMBL:EYU21742.1, ECO:0000313|Proteomes:UP000030748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. DUN x IM62 {ECO:0000313|Proteomes:UP000030748};
RX PubMed=24225854; DOI=10.1073/pnas.1319032110;
RA Hellsten U., Wright K.M., Jenkins J., Shu S., Yuan Y., Wessler S.R.,
RA Schmutz J., Willis J.H., Rokhsar D.S.;
RT "Fine-scale variation in meiotic recombination in Mimulus inferred from
RT population shotgun sequencing.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:19478-19482(2013).
CC -!- FUNCTION: Magnesium transporter that may mediate the influx of
CC magnesium. {ECO:0000256|RuleBase:RU366041}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU366041}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU366041}.
CC -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC
CC 1.A.35.5) family. {ECO:0000256|ARBA:ARBA00007535,
CC ECO:0000256|RuleBase:RU366041}.
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DR EMBL; KI632223; EYU21742.1; -; Genomic_DNA.
DR RefSeq; XP_012856191.1; XM_013000737.1.
DR AlphaFoldDB; A0A022PZI3; -.
DR GeneID; 105975541; -.
DR KEGG; egt:105975541; -.
DR eggNOG; KOG2662; Eukaryota.
DR OMA; RNFDNVF; -.
DR OrthoDB; 73031at2759; -.
DR PhylomeDB; A0A022PZI3; -.
DR Proteomes; UP000030748; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015693; P:magnesium ion transport; IBA:GO_Central.
DR CDD; cd12823; Mrs2_Mfm1p-like; 1.
DR Gene3D; 2.40.128.330; -; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR InterPro; IPR045863; CorA_TM1_TM2.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR InterPro; IPR039204; MRS2-like.
DR PANTHER; PTHR13890:SF26; MAGNESIUM TRANSPORTER MRS2 HOMOLOG, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13890; RNA SPLICING PROTEIN MRS2, MITOCHONDRIAL; 1.
DR Pfam; PF01544; CorA; 1.
DR SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion transport {ECO:0000256|RuleBase:RU366041};
KW Magnesium {ECO:0000256|RuleBase:RU366041};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU366041};
KW Reference proteome {ECO:0000313|Proteomes:UP000030748};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU366041};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU366041};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU366041}.
FT TRANSMEM 381..405
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT TRANSMEM 417..437
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU366041"
FT COILED 224..251
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 445 AA; 50507 MW; 105DD519750C0FB0 CRC64;
MADLKERLLP SKPASALNLR DSSYRPSASG RLPFQGVDVS GLKKRGQGLR SWIRVDVSGN
SQVIEVDKFT MMRRCDLPAR DLRLLDPLFV YPSTILGREK AIVVNLEQIR CIITADEVLL
LNSLDSYVLQ YVVELQRRLQ AAGVGEVWQS EGHEVHRRRG SRNFDNMFAN SSPDYLPFEF
RALEVALEAA CTFLDSQAAE LEIEAYPLLD ELTSKISTLN LERVRRLKSR LVALTRRVQK
VRDEIEQLMD DDGDMAEMYL TEKKRRMESS FYGEQSLIGY RSNDGALSVS APVSPISSPP
DNRRLDKSLS IARSRHESVR SSSEDATENI EELEMLLEAY FVVIDSTLNK LTSLKEYIDD
TEDFINIQLD NVRNQLIQFE LLLTTATFVV AIFGVVAGVF GMNFAIPMFD NPGAFKWVLI
ITGVCGAIIF ATFLWFFKYR RLMPL
//
