ID A0A024FZ43_9STRA Unreviewed; 4160 AA.
AC A0A024FZ43;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=BN9_001030 {ECO:0000313|EMBL:CCI39320.1};
OS Albugo candida.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI39320.1, ECO:0000313|Proteomes:UP000053237};
RN [1] {ECO:0000313|EMBL:CCI39320.1, ECO:0000313|Proteomes:UP000053237}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI39320.1,
RC ECO:0000313|Proteomes:UP000053237};
RA Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA Jones J.D.G.;
RT "Recombination and specialization in a pathogen metapopulation.";
RL Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCI39320.1}.
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DR EMBL; CAIX01000001; CCI39320.1; -; Genomic_DNA.
DR STRING; 65357.A0A024FZ43; -.
DR InParanoid; A0A024FZ43; -.
DR OrthoDB; 312149at2759; -.
DR Proteomes; UP000053237; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00102; IPT; 1.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR017868; Filamin/ABP280_repeat-like.
DR InterPro; IPR001298; Filamin/ABP280_rpt.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF8; DYNEINS HEAVY CHAIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF00630; Filamin; 1.
DR Pfam; PF13415; Kelch_3; 1.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF12777; MT; 1.
DR Pfam; PF01833; TIG; 1.
DR SMART; SM00382; AAA; 2.
DR SMART; SM00557; IG_FLMN; 1.
DR SUPFAM; SSF81296; E set domains; 2.
DR SUPFAM; SSF117281; Kelch motif; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
DR PROSITE; PS50194; FILAMIN_REPEAT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053237}.
FT REPEAT 439..561
FT /note="Filamin"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00087"
FT DOMAIN 1399..1537
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2052..2202
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 2648..2675
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2905..2953
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4160 AA; 469270 MW; A1076B4721B01559 CRC64;
MPIGYGFEPE VVWTAPKQTG DIPVKRSGHS LTLKSADSET TAYLFGGCDH KAIPGPTDDL
YKLDLTGNAY NWTRLNPPSN VSEDFPPPRW RHSAVFYRNR YLVIFGGFAA DKRMNDVWVF
DSTTRLWEQK YAQGIWEGLP QCRGAHTATL LGQKMYIFGG YGGAGYGRTD FNDLHVLDLE
LWKWGEIITD GDRPEPRSGH QTCVINESQL IVIGGWNSLK QFQDAFICDL NDRKWKQATM
KAPMPIWNHA CVSVESGPQW KVFMFGGSSG DGAESSSIPG SFLNSVMVFN TGTMAWSSPP
VKGEPPHPRA DTSIVLDTAN NRILVFGGWA NRWFSDLYVL QVGEIIGPPY AISSIEPSSG
PITGNTKVTI GGYKFNAPSA TVRFAVTKGY ADVIGSVVSS TRIEATAPNF EKYGSLQSEV
RVSLSGAAYT NVCTTFKFHS VTIASKTVAF GPSIISTLNT LSVVGNPTTL VIQARDKDNL
PRDCGGDDFT ITLSPILNLE EAPPSDAESF EITNIEDKAD GTYIVTFVPP QAGTWNISIV
FNGTYNGQAG HIRGSPFQST FMSSADASTS KRAGDLMPPI MSEKEFDNSD LVRTFMAGLN
RRSTEYRRVL MDLRKEIPSH ETNGLDILRR TKETLGRLET EKAGNQLLLD QSRQWMTHLK
RIGASVDKEL GEIEHIEKQF TEVLKQIPLT EQNIQEPTRI FSEKTEEKMA IYHQSIVQKS
VTLKKNDFWS SHLEPEKALE RIQQYISDWE NDMKECGEKT KLCQTFGFAH IMNNSIALMQ
KMRLDVEALA KVWSIVQRAR TFVGQAHEMV FQQVDVNQLQ IENQSMLKEL KKTPKDVQWC
EAYTTILNEC QAFEKTHPLI RSLLASYMQT RHWNRIMAHT GTFTTPKEDP TQRLGVLLSR
NLYRFTSEIT EICYEAEKEQ ELELRLNDLE GIWAQVNWEM TPYNQKATIE SQVDGDSAQS
NADSSEAFVP LIRISEENFE LLETHQIDVQ TMSASPYQSE FESRVNDLQI GLSSINEVVV
LLSDIQRSWS YLEPLFVQSE EVKKQLPELT LDFEEIDVQV RIILREAWQT LNVKQSSTKP
DLLHQLGKLM DALDQCKSRL KEFLDGRRRQ FPRFYFMSEA DLLDILSNGA HPERIMPHCS
KIFLATKTLT LTNDCAGDNS QRPVATQFVA GVGQEVVDLV EPLKLEGEAE IYLDVILRAM
RTTLSQQITR SLKSYTELSR VDWINQKDST GKIMDAAQII LLAAGIHYVQ EVELSFRRMI
TGDDKDAMIQ YNKKQEKQLE DLIRLTQSNI SSAERQRVMV LITMDAHGRD IVANMIRDGV
EDASSFQWQS QLKHYFSPAQ GSFLKRDKAF RGPHDERAQI LICDAGMPYD YEYLGNGPRL
VITPLTDRIY VTATQALNLK MGCAPAGPAG TGKTETTKDL ANALGKVCYV FNCSPEMDYK
SLGNIFKGLA SSGSWGCFDE FNRLVPEVLS VCSVQFKAVC DACKADDEVF LLEGDRINLD
PTVGAFITMN PGYLGRSELP EGLKALFRPM TVMVPDLVLI CENMLMAEGF TQAKILASKF
YGLYSLLGQL LSKQLHYDWG LRAVKSVLVV AGAFKRAEPD IPEIDLLMRA LRDFNIPKIV
TEDSVIFFGL LGDLFPRQDP NIDVRNDPPR KRDVELETMV QDAARAIHNS PRPEFMLKVV
QLAELLAIRH CVFVMGPPAC GKTETWKTLK KARELMGTSM EVQDLNPKAV STNELYGYIV
LKTREWRDGL LSRIMRDLGS RRKDNGDEDE SPKWIILDGD LDANWIESMN SVMDDNRMLT
LASNERIPLK SHMRMIFEIR DLMYATPATV SRAGILYIST LEGYQWRCLI DSWLQRHSSA
NQPDTRDTES RATANRAVVR NGILLFSADI AGKFTTLFEQ YIEPTLRFFK KKLRPIVPVE
ETTLITNLLN MLDCLLTPQV VQDFNLMQSS FVFCCVWAFG SVLTLSDDGT DYAVAFSTWW
KTQWKDVKLV TSASNTVFDF WLDVDTAKFN SWAKSPYFYT ETYQSPAPIN QITVPTTETS
SIAFWLEKLL IKQIPVMICG PAGTGKTQNV VGMLKKLSKD DANTAFRYAS INFNFYTTSA
ILQQAMMSQL ERKTGLNLGP PGKANLIFFI DDLNLPEMDP YNTQSAISLS RQVLEYKHWF
DRSKLQQQNI LNVQFAAAMN PTAGSFLIDP RLQRHFCTFA MGMPEAPSLV TIYETFLSGH
LAGFSEELSN STFTNALIKA ALMLHTNVVS TFRKTAANFH YEFNVRHLSN VFQGLITSSK
QRFQTAEKFI FLWLHESERT YGDRLVCKSD LEKYSQLVQL QVKRSFPSCN TTRYFAAKNA
WPLLFCHFTR DGDAEYDQVM EPSLEVLKTN LQHQLREYNS NENNSAMHLD LFDDAIRHVA
RIVRILKNDG GHALLVGVGG SGKRSLARLA SYICGYTVVQ VTISSKYGEN EFKEDLKKMH
LLIAEMLSRN EEDAGIVFML TDSQITNEKF LIYLNDLLAS GEIPDLLAVE DYDTIVGSIT
PVVQTKDRKE IIKFFQAQLR QRLHLCLCFS PVGDDFRNRA RKFPALVNCT VIDWFQPWPH
EALLSVGREK LREINDLLGP EDSRAGIENF MPYSFQSVNQ CAERFFQVER RHVYTTPKSY
LELLQLYKKI LKQKFQEYTT AIDRLEKGLQ KLKETGETVS RLEVELKVKL EAAEDKKSVA
SQIAETVNLE KARVEVESKK ASDEADKCAI IQAEVIERQR STSEDLAKAE PAVQQAMEAL
NSLNKKDLGE CKTMSKPPTG VDEIFAATMV LLAGVHPNVQ VTKTGKVKDV KWDTVKKQLL
GNIPEYIEYL VNFKSVVDDG KVPVLNWKEV REFLDKEYFN PEVILTKNKA AAGLCSWVIN
IVMYYDILIT VEPKRQALLA ANMELEAANK RLHEVTTLVA ELQAKLDKLL EEAAAAEKEK
EEAIASVEQG NRKMKLAGTL TKDLSSENIR WGVNVLQLQK EKDLLVGDVL LACAFISYIG
PFTKPFRDEL ISKHWVPYLR EAANGSSIAM SEEANSLAIL TNDAQIAEWN TQKLPSDRVS
TENGAIVVTT VSMGRRPLII DPQLQAIAWI REMEAKNNLI IVRAGQKMWI DRLKVAIGTD
GAFLIENLGE KIDPILAPVI QRSTCRRGAR LEIQIGDASV PYNENFHLYL HTKLGNPHYP
PEIQAECTIV NFTVTALGLE DQLLNLVVSK ERADLAIKRE HLIHQQNQGK IELKKLEDDI
LFYLASADDD ITNNQPLISI LSDTKHKAQL TQKSMEAAKK TQESVNITSE KYRSIASRGS
LLFFLMNDIS KVHSYYIYSL ASFQQVFLQG IYSVPIERAP IAVVDVEDGA YEDTGKTDIN
DQENALDLSD EEMKQRCDAS MQSITRCVYN YVRRGLFERD KLTVAMMLCL TILIKENVLS
PLEVEHFLIS KGQSDAGNAG VASEWLSSAL WSKLKALETL KCFHGLGDGI QNDPDEWRKW
FAAEDAEKQS IPGDFASLSG FQRIILLRCL RPDRVTNALR TFISDSLGES YVTQAPFDMD
ATYRETSFAV PIFFVLFPGV DPTSWVEALG RNRNVGVEHN NFINISMGQG QESYAQESLA
RLSSQGGWII LQNVHLMQSW LPTLERQLEE IATEGAHDNF RCFISAEPPP LPDMLNIPES
LLQSCIKVAN EAPADIQSNL RRAWSNFSQE KINSCSKPRE YKACLFALCW FHAIVLGRRR
FGQQGWSRAY SFNTGDLSIC ANILQSYLDA NEAVPWDDLR YIFGEIMYGG HITDSWDRRT
NNTYLNVLLH PTLMSGMELG PGFASPDPVD FDFEAYATYI DKNMVPEAPP LFGLHPNAEI
GYLTTTCETL CYTIVTVRGG VSDGDTDGDK TLALASAIDD FEARCPECFS MFDVVEAATP
LLTQEHGPFV VVLLQECSQM NVLLEEIKTS LSDLKKGLYG QLNMSQAMED LATAIGLNEV
PGRNPFSLCK WEKKAWPSKK SLSSWFQDMI LRYAQLEAWK SDFNTPYSMW LPGLFNPTAF
TTACLQVTSR RRLLPLNQMT VETHVTVFHD VSQINYYPDD GVFVHGLILE GARWSTSDEI
VDRTFVGEQP ATECGGMLLD SFPKQLLWPM PIVYVKAVQT KPQWEPTSVG YLRHDPSLYE
CPVIGSREMD FAWCCDRFSR
//
