ID   A0A024GK25_9STRA        Unreviewed;       324 AA.
AC   A0A024GK25;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   13-SEP-2023, entry version 26.
DE   RecName: Full=HIT domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=BN9_078130 {ECO:0000313|EMBL:CCI46858.1};
OS   Albugo candida.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Albuginales; Albuginaceae; Albugo.
OX   NCBI_TaxID=65357 {ECO:0000313|EMBL:CCI46858.1, ECO:0000313|Proteomes:UP000053237};
RN   [1] {ECO:0000313|EMBL:CCI46858.1, ECO:0000313|Proteomes:UP000053237}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ac Nc2 {ECO:0000313|EMBL:CCI46858.1,
RC   ECO:0000313|Proteomes:UP000053237};
RA   Gardiner A., Kemen E., Schultz-Larsen T., MacLean D., Van Oosterhout C.,
RA   Jones J.D.G.;
RT   "Recombination and specialization in a pathogen metapopulation.";
RL   Submitted (MAY-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HIT family. {ECO:0000256|ARBA:ARBA00010208}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCI46858.1}.
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DR   EMBL; CAIX01000143; CCI46858.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A024GK25; -.
DR   STRING; 65357.A0A024GK25; -.
DR   InParanoid; A0A024GK25; -.
DR   OrthoDB; 5490768at2759; -.
DR   Proteomes; UP000053237; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   GO; GO:0000290; P:deadenylation-dependent decapping of nuclear-transcribed mRNA; IEA:InterPro.
DR   Gene3D; 3.30.428.10; HIT-like; 1.
DR   Gene3D; 3.30.200.40; Scavenger mRNA decapping enzyme, N-terminal domain; 1.
DR   InterPro; IPR008594; DcpS/DCS2.
DR   InterPro; IPR036265; HIT-like_sf.
DR   InterPro; IPR011145; Scavenger_mRNA_decap_enz_N.
DR   PANTHER; PTHR12978; HISTIDINE TRIAD HIT PROTEIN MEMBER; 1.
DR   PANTHER; PTHR12978:SF0; M7GPPPX DIPHOSPHATASE; 1.
DR   Pfam; PF05652; DcpS; 1.
DR   Pfam; PF11969; DcpS_C; 1.
DR   PIRSF; PIRSF028973; Scavenger_mRNA_decap_enz; 1.
DR   SUPFAM; SSF54197; HIT-like; 1.
DR   SUPFAM; SSF102860; mRNA decapping enzyme DcpS N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053237}.
FT   ACT_SITE        262
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR028973-1"
SQ   SEQUENCE   324 AA;  37578 MW;  7DE4C7F5950D5651 CRC64;
     MIKWTKAIGM TATAVTGLLF IRYRLRKKRS ILTDLRSFRP RETLRVTEAD FAILGTFEDD
     QKSAVLVIEK LPFHRADRNH WLQNLTLCQN LQNDVYTSYR ASISQKLEPF KVTVIYPATK
     EHIQKYTEQK FCIVRETPTI YNTITEPFIA SIPASKLDWI SNILEHKSEV ERILYEDADK
     KAGFIFLPNS RWCQLNKKEA LNCLAIVRNR SLRSIRDLTA EHLPLLCNIR DTCLEVIRKQ
     FQVEASSLRI YFHYQPTYYH LHVHFTHLNI SNGVSLGKAI FLDDVIYNLT RQSNHYKEAV
     LTYVVGKSQH ASLYANLVAA NAIA
//