ID A0A024P6X5_9BACI Unreviewed; 740 AA.
AC A0A024P6X5;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=ComEC family competence protein {ECO:0000313|EMBL:CDQ24411.1};
GN ORFNames=BN983_02691 {ECO:0000313|EMBL:CDQ24411.1};
OS Halobacillus karajensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Halobacillus.
OX NCBI_TaxID=195088 {ECO:0000313|EMBL:CDQ24411.1, ECO:0000313|Proteomes:UP000028868};
RN [1] {ECO:0000313|EMBL:CDQ24411.1, ECO:0000313|Proteomes:UP000028868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HD-03 {ECO:0000313|EMBL:CDQ24411.1,
RC ECO:0000313|Proteomes:UP000028868};
RA Urmite Genomes U.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDQ24411.1, ECO:0000313|Proteomes:UP000028868}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HD-03 {ECO:0000313|EMBL:CDQ24411.1,
RC ECO:0000313|Proteomes:UP000028868};
RA Khelaifia S., Croce O., Lagier J.C., Raoult D.;
RT "Draft genome sequence of Halobacillus karajensis HK-03.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDQ24411.1}.
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DR EMBL; CCDI010000003; CDQ24411.1; -; Genomic_DNA.
DR RefSeq; WP_035509217.1; NZ_CCDJ010000004.1.
DR AlphaFoldDB; A0A024P6X5; -.
DR Proteomes; UP000028868; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000028868};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 248..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 311..330
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 336..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 426..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 458..480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 493..687
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 740 AA; 84003 MW; 7226BD6F70B1C670 CRC64;
MLNLKGNWHI LAIAFVLGGV LSNQEGLAVY LILILLMAWL FIYRFHFLHS TLLLLFVFIG
YTYLSPISPN VLSHSSPAKW EGIITPEIKN TEHTLSLILK DKSGDKKQIR YIKKDDEDIH
PQWKVGATCI VEGNVEPFEA ARNPGQFDYQ SYMGRMGIFS QVIIKEPSNL TCEGESWMNQ
LLESREILKG KVKTNVSDYT FSSIVDWFRE FNLSHILAIS GLHVGLTIGG LYWLFFRSGL
ITKRQSKFIL VVFLPVYMFL SGGAPSVMRA GLMAGVLMLT GSFQRKFPLT DILSIICLLF
LFLSPSYFHH IGFQFSFLVT FSLLLTIPIL KHYTNTWMQS AVIGLTSQLS ILALQVHYFY
EFQPFSLWMN MIAVPYFSFF VIPGLMVILV VSFLYPPFSS FLSSLFQDVH EIVLSYMIHI
SECLDFLWVI GEISMPYVVL YTLCFIQMMR IWEKGEKWKT FLASCAVVGV FIVWCLSPYL
SEKGTLTMLD VGQGDSFIIE LPYRRGIVMV DAAGPPVYAS NKERTAEDVI LPYLKSKGIH
RIDAMFITHD DTDHSGSAPY IVDDIDVHRI YVSPYHKEEY HVAGKAERIK AGQKLLVGDH
AFDVLHPSDV DHKDSNENSL VLHSIIGGKQ WLFTGDISKR IEQGIVEHYP SLKVDVLKVA
HHGSHTSTSD ELLKAFQPRL AMITAGVNNR YGHPHQDVTD RLHENGVLLL QTNHHGAVQY
IFSEQTGTFS TFLPYNASRE
//
