ID   A0A024UEE4_9STRA        Unreviewed;       732 AA.
AC   A0A024UEE4;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 36.
DE   RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE            EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN   ORFNames=H310_04585 {ECO:0000313|EMBL:ETW04257.1};
OS   Aphanomyces invadans.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Aphanomyces.
OX   NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW04257.1};
RN   [1] {ECO:0000313|EMBL:ETW04257.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NJM9701 {ECO:0000313|EMBL:ETW04257.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA   Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA   Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA   Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA   Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA   Nusbaum C., Birren B.;
RT   "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC         Evidence={ECO:0000256|ARBA:ARBA00001556};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI913958; ETW04257.1; -; Genomic_DNA.
DR   RefSeq; XP_008867213.1; XM_008868991.1.
DR   AlphaFoldDB; A0A024UEE4; -.
DR   STRING; 157072.A0A024UEE4; -.
DR   EnsemblFungi; H310_04585-t26_1; H310_04585-t26_1-p1; H310_04585.
DR   EnsemblProtists; ETW04257; ETW04257; H310_04585.
DR   GeneID; 20081635; -.
DR   VEuPathDB; FungiDB:H310_04585; -.
DR   eggNOG; KOG0922; Eukaryota.
DR   OrthoDB; 5488182at2759; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF136; ATP-DEPENDENT RNA HELICASE DHX35-RELATED; 1.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00487; DEXDc; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT   DOMAIN          46..207
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
FT   DOMAIN          239..409
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          681..732
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   732 AA;  81314 MW;  1CB4FA5798E2CD16 CRC64;
     MHRQSTGGMW VPGVKKAQMS DRGEEQLPPV VSVSSLPIEA REKEILYAVE TSSVVILAGE
     TGSGKTTQTP QYLYRAKFGK IAVTQPRRIA AITVAERVAS EMGVRLGGEV GYAVRFEEKW
     DPERTGIKFL TDGMLVRETM LDPLLSHYNV IMLDEAHERN LETDILLGLI KKIMKKRLDL
     RVIVASATLH VEAFERFFSS IKHEGGVIKP VVSIAVQGRQ YPVDVLYLKE PAANFEQKTI
     DTVLAIHERE AQGDILVFLP GQEEIDHVVH RLSQSASRTL LPLAFYGSLP VHVQQAVFDP
     TPPHVRKVIV ATTIAETSVT IPGVVYVVDS CFVKLPFYNP LTGIEALVTT VESKAAAKQR
     AGRAGRMRPG KCFRLVTEAT YRKTFPKHTI PQIQRTNLAP IVLHLLSMGI QDIVHFDFLS
     PPTPEALVRA LEILYSLGAI SKDCVLVEPL GAHMAEFPVD PCLSKMLLAS FDFGCTEEAL
     TIASMVSVDD IFIHPRASKE RQLKLKEAVA EFAHQQGDHI TYLHIYNEFL ENDCSRSWCD
     EHCLNHRILM RATEIRKQLH RYVKRFATAD NAIHSCGDDK QPVLQCLVAG FFANAAKLHG
     SSTYRTIKDG RIVHVHPTSV LNSFIRSPEW IVYHQSVLTD KEYVREISSI DPRWLVAAAP
     EYYYCKDVSA VVSGSSGDIG LPKAPPPTAQ QPAATDANGR ILFRRPTPSS TATTKKLPVH
     IGKSKGGLRS QF
//