ID A0A024UIA2_9STRA Unreviewed; 1059 AA.
AC A0A024UIA2;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Calcium-activated potassium channel BK alpha subunit domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=H310_03753 {ECO:0000313|EMBL:ETW06176.1};
OS Aphanomyces invadans.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Aphanomyces.
OX NCBI_TaxID=157072 {ECO:0000313|EMBL:ETW06176.1};
RN [1] {ECO:0000313|EMBL:ETW06176.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NJM9701 {ECO:0000313|EMBL:ETW06176.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., van West P., Dieguez-Uribeondo J., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Aphanomyces invadans NJM9701.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI913956; ETW06176.1; -; Genomic_DNA.
DR RefSeq; XP_008865953.1; XM_008867731.1.
DR AlphaFoldDB; A0A024UIA2; -.
DR EnsemblFungi; H310_03753-t26_2; H310_03753-t26_2-p1; H310_03753.
DR EnsemblProtists; ETW06176; ETW06176; H310_03753.
DR GeneID; 20080803; -.
DR VEuPathDB; FungiDB:H310_03753; -.
DR eggNOG; KOG1420; Eukaryota.
DR OrthoDB; 47991at2759; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR003929; K_chnl_BK_asu.
DR InterPro; IPR013099; K_chnl_dom.
DR InterPro; IPR047871; K_chnl_Slo-like.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR PANTHER; PTHR10027:SF10; SLOWPOKE 2, ISOFORM D; 1.
DR Pfam; PF03493; BK_channel_a; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 285..342
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT DOMAIN 495..583
FT /note="Calcium-activated potassium channel BK alpha
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF03493"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..911
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1059 AA; 117095 MW; 3E8E3E8862EBAB43 CRC64;
MSGRSNTSGY SSRMDNPPKH SEAVSPSRKR RLNPQHSVTR RQSIHDLVTM TVVPQLEHIK
DPRSRGLLFL VRNSGESRRD FTLRNLEQSN AGHLVDMFMV FLSLFWVAVY IYVNKNVANP
KLPTEVQVLS HTLGVVFLLD YLVRLYASPL RVSHFWSFFP LVDFISLVPM VIEIVVGNDV
LTHISKQTDS LRQVASMLQA AKTIRILRAY RALKFIKSTV NRQMAATGLT VVCIIIAMAG
ILQILDQCSP ACDNFMFCSS DFSAYECPRS AACYEADVVH NCCKCQELSF FDWTYFVVVS
ISTLGYGDIS PRGRLARLAT STMMLMTFVL VPIQINRLVA TISTHSGYTS SYKEHRTHTH
GIITAGGDIS AGTLANFLRQ FFHPNNPNWN EKIVILHPTA PSNDVQRVIH MHEPRVQYIV
GSAMNDLDLD RAMISKAAVC YVLVNKDTSR PSNEDQSCTL LTAAFRGMNA AVPVYSQVFM
SQNISHCVLS GATGVICVEK LKLGVLGLNC TVWGLSTLLS NLLDTVSPSV TQLYPKDSWE
TAYLKGYLHE IHRVDIPRSF SGLTYRDLIL FLFGTLQVIP IAMLTDKGVS FAPMDFKLGA
TADPTICCTL YILAPYVTVA DQIAEYPLEQ IRLFRQTLRK QERHVAERNE AAALESAAAV
PPPSVPSAPL HVPNGHDEDA TKASTASTAF SALAKGLHGV KHAFGQASPY KEFMAKLLPE
QLNDHVVIVG LPASLGDIIV PLRQFNARNT CGKAQAIVFI APFAMSEHHY HSIGDSTAVY
FVQGSPLSSF DLHRIHIDTA SAIIILAGSG SKRKYIDENM VDADAITTVR YINEACSGSK
PPNLIVELVK ATNVKFMSSI VKRHMNHHRR RHSDGRHTRV VGTVTAHKYM PTDAAPPPRP
GDGGPTPNKV ENEDKIDVEH ICEPSYASGR VYVSGMIDSL MSECYQKPNI IPAINLLMFG
SPTDPEYVVV VVHVLGCRHG RGGSAQRLFQ VRTPKSLHGK TFGECFRKVL ALNLICIGCL
HSSTDKTPPY VHTNPPADMI IYQTDYIYVI GKPCSDLPL
//
