ID A0A024WRV9_PLAFA Unreviewed; 821 AA.
AC A0A024WRV9;
DT 09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT 09-JUL-2014, sequence version 1.
DT 22-FEB-2023, entry version 15.
DE RecName: Full=MACPF domain-containing protein {ECO:0000259|PROSITE:PS51412};
GN ORFNames=PFMALIP_02521 {ECO:0000313|EMBL:ETW49430.1};
OS Plasmodium falciparum MaliPS096_E11.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=1036727 {ECO:0000313|EMBL:ETW49430.1, ECO:0000313|Proteomes:UP000030699};
RN [1] {ECO:0000313|EMBL:ETW49430.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW49430.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Hoffman S., Volkman S., Rosenthal P., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W.,
RA Alvarado L., Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J.,
RA Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A.,
RA Ireland A., Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Annotation of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETW49430.1, ECO:0000313|Proteomes:UP000030699}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MaliPS096_E11 {ECO:0000313|EMBL:ETW49430.1,
RC ECO:0000313|Proteomes:UP000030699};
RG The Broad Institute Genome Sequencing Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Cheeseman I., Volkman S., Adams J., Walker B., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Neiman D., Pearson M., Priest M., Roberts A., Saif S., Shea T.,
RA Sisk P., Sykes S., Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium falciparum MaliPS096_E11.";
RL Submitted (FEB-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI925543; ETW49430.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A024WRV9; -.
DR EnsemblProtists; ETW49430; ETW49430; PFMALIP_02521.
DR Proteomes; UP000030699; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR020864; MACPF.
DR PANTHER; PTHR19324:SF33; APEC DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR19324; PERFORIN-LIKE PROTEIN 1; 1.
DR Pfam; PF01823; MACPF; 1.
DR SMART; SM00457; MACPF; 1.
DR PROSITE; PS51412; MACPF_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030699};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 225..577
FT /note="MACPF"
FT /evidence="ECO:0000259|PROSITE:PS51412"
SQ SEQUENCE 821 AA; 93291 MW; A8FA2E8D459F3789 CRC64;
MTFTRGSFIF LYILIIILNT IYQNIFDNID NVSFISKIFS SKIFVSTKGN DYIENTVENI
PQIENGKILN ILQHDQIINK VNHNTIHTGA LYTQHNKKSK NRKTIKSSQR KSHPNLVNVK
NNINFNEIKN GHETNTNDSL FKTEEIKKIE ATEKKECKGS AKNCIRGNVK SLINVMKGME
INKNEKDNST LDREENIYDD EHHTVIVFDG IDENKDLYNK YKNIEKNKNG MDSIVIQGTE
YLGVGYDFIF GNPIGDPFLK VDPGYRDSII KLTYPKSDED YPDNYMNINP NGSFVRNEIS
CNRSEKESEI STMSEYTKEL SVDASIGASY GLFGSFSAST GYKSVSNTIS KNKFRMFMLK
SYCFKYVASL SQYSQWKLTD QFVRAISLLP SHFNSLEKDG TYCSDEEFRD NRKSEKCGKS
VTAWMYFFKN FGTHVSTLLH LGGKITQQVK ISKNDYKAMT ESGLSISASV SAGFGLFKVK
GSTNTESNES SNNESSTSSL EKETVIIGGT TIFDPNDPNN FEKWAESISE NPMPIKGEYE
PLSRILPTRL SKIYEEALRF YISVNVPSNF GQITDNEIRQ YNIKEELMKA TMIHSSGTGL
VVVECEEKQN FLLGFSLSIP NDLSNLKDFY LNSCDEDSDK CYSKMSDNAY SYIFAMCKEE
MIPFFEQKVK SGVGLLTLEC SEKNQVILFG FGISVLNTND PISISLYPCK YGKASCSMQG
STDQSAVGLW IVCAHEESLN SKFSVYIRKM FEENVSGKKK KHMDICPEKV LFNLIFEFTK
TPIKKRNGGC FTVNDKCPKD FHVCSEKKDR KSFNYYSLSV Y
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