ID   A0A059CTZ5_EUCGR        Unreviewed;      1196 AA.
AC   A0A059CTZ5;
DT   09-JUL-2014, integrated into UniProtKB/TrEMBL.
DT   09-JUL-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=RNA-dependent RNA polymerase {ECO:0000256|RuleBase:RU363098};
DE            EC=2.7.7.48 {ECO:0000256|RuleBase:RU363098};
GN   ORFNames=EUGRSUZ_C02782 {ECO:0000313|EMBL:KCW81405.1};
OS   Eucalyptus grandis (Flooded gum).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Myrtaceae; Myrtoideae; Eucalypteae; Eucalyptus.
OX   NCBI_TaxID=71139 {ECO:0000313|EMBL:KCW81405.1};
RN   [1] {ECO:0000313|EMBL:KCW81405.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Leaf extractions {ECO:0000313|EMBL:KCW81405.1};
RA   Schmutz J., Hayes R., Myburg A., Tuskan G., Grattapaglia D., Rokhsar D.S.;
RT   "The genome of Eucalyptus grandis.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probably involved in the RNA silencing pathway and required
CC       for the generation of small interfering RNAs (siRNAs).
CC       {ECO:0000256|RuleBase:RU363098}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC         RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC         COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC         EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517,
CC         ECO:0000256|RuleBase:RU363098};
CC   -!- SIMILARITY: Belongs to the RdRP family. {ECO:0000256|ARBA:ARBA00005762,
CC       ECO:0000256|RuleBase:RU363098}.
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DR   EMBL; KK198755; KCW81405.1; -; Genomic_DNA.
DR   RefSeq; XP_010048974.1; XM_010050672.2.
DR   AlphaFoldDB; A0A059CTZ5; -.
DR   STRING; 71139.A0A059CTZ5; -.
DR   EnsemblPlants; KCW81405; KCW81405; EUGRSUZ_C02782.
DR   GeneID; 104437677; -.
DR   Gramene; KCW81405; KCW81405; EUGRSUZ_C02782.
DR   KEGG; egr:104437677; -.
DR   eggNOG; KOG0988; Eukaryota.
DR   InParanoid; A0A059CTZ5; -.
DR   OMA; VTYHPNW; -.
DR   OrthoDB; 5477883at2759; -.
DR   GO; GO:0031380; C:nuclear RNA-directed RNA polymerase complex; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IBA:GO_Central.
DR   GO; GO:0030422; P:siRNA processing; IBA:GO_Central.
DR   CDD; cd00590; RRM_SF; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR   InterPro; IPR000504; RRM_dom.
DR   PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR   PANTHER; PTHR23079:SF18; RNA-DEPENDENT RNA POLYMERASE 6; 1.
DR   Pfam; PF05183; RdRP; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   3: Inferred from homology;
KW   Nucleotidyltransferase {ECO:0000256|RuleBase:RU363098};
KW   RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW   ProRule:PRU00176};
KW   RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW   ECO:0000256|RuleBase:RU363098};
KW   RNA-mediated gene silencing {ECO:0000256|RuleBase:RU363098};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU363098}.
FT   DOMAIN          13..115
FT                   /note="RRM"
FT                   /evidence="ECO:0000259|PROSITE:PS50102"
SQ   SEQUENCE   1196 AA;  137357 MW;  2EA9FCC939C9BDD0 CRC64;
     METKRARKDI VMAQISVSGF DQNVTAKELV KYLENTVGPI RRCRLKTSWT PPDSYPDFEV
     TRFDTMHLVN EYRKVEPHAF VHFALPEAAT SAHELSLHNG LFLNNKRLKV SLGPENPFHA
     NQRRTTTPFK LPEVCLEIGN LIAPKEFLVG WRGPSSGVDF FVDPFDSKCR FCFTRKTALS
     FKDLSFYAVI NCEFKMEFLV SDIIEISQYR EMSSIVIFLQ LGSAPRVYYR TADDDMEIPV
     SLDLLDDQDP WIRTTDFTVS GAIGRCNTYR VSVPPHHGLK LKKAMDYLRG QRVQECSPRR
     FLKIQDEPNF GRPMFDAFFS IHQEGIPFDV MFLLNAVIHK NVFNQHQLSE SFYGLLKSQP
     KEVNIAALKH ICSFKRPVLD ADKKLKLVQE WLLKNPILVK NQKELNDIVE IRRLIVTPTK
     AHCLPPEVEL SNRVLRHYKD VADRFLRVTF MDEGLEMINA NVLNYYVAPI LKDIKSVSFS
     QKTTIFKRVR TIVMDGFSLC GQRYSFLAFS PNQLRDQSAW FFAEDKDIDV KRIWAWMGKF
     NNRNVAKYTA RMGQCFSSTY ATVEVPRKEV HHDLPDIERN GYCFSDGIGM ITPDLAREVA
     EKLKLELNTP AAYQIRYAGY KGVVACWPRK GDDGIRLSLS RSMNKFQSNH TTLEICSWTT
     FQPGFLNRQI VTLLSALKVP DEVFWDMQEK MVFKINQMLV DSDVAFDVLT SSCAQQGNTA
     AIMLSAGFRP QSEPHLKGML MCIQAAQLWA LKERARIFVP SGRWLMGCLD ELGVLEQGQC
     FIQVSSPALE NCFIKHGSRF SETKKNRQVI NGCIVVAKNP CLHPGDIRIL EAVDAPELHH
     LYDCLVFPQN GERLHTNEAS GSDLDGDLYF VTWEENLIPP SKKSWTPMQY DSGEEKKLPR
     DVTQKDIKDF FVKHVLNENL GTICSAHMVH ADRSEHGALD ENCILLAELA ATAANFPKTG
     KLVTMPRHLK PKQFPDFIGT EEFQTYKSTK ILGRLYRQIK DAFDEDLNSS EPNCIPKDIP
     YDKSIEVPGA PNFIYEAWDH KCSYDGQLSG LLGQYNVNNE VELVTGHVWS MPKYASRKQR
     ELKERLKHSY TALRKEFREK FEMLDSYYEL LSDEERNLLY EQKASAWYQV TYHPNWVKKS
     VDLHEHDDGG TSTLKLSFAW IAADFLARIK IRKQYGRNLD SAKPINSLSK YFADRI
//