ID A0A060LYG0_9BACI Unreviewed; 679 AA.
AC A0A060LYG0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=BleG1_2237 {ECO:0000313|EMBL:AIC94815.1};
OS Shouchella lehensis G1.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Shouchella.
OX NCBI_TaxID=1246626 {ECO:0000313|EMBL:AIC94815.1, ECO:0000313|Proteomes:UP000027142};
RN [1] {ECO:0000313|EMBL:AIC94815.1, ECO:0000313|Proteomes:UP000027142}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=G1 {ECO:0000313|EMBL:AIC94815.1,
RC ECO:0000313|Proteomes:UP000027142};
RX PubMed=24811681; DOI=10.1016/j.gene.2014.05.012;
RA Noor Y.M., Samsulrizal N.H., Jema'on N.A., Low K.O., Ramli A.N.,
RA Alias N.I., Damis S.I., Fuzi S.F., Isa M.N., Murad A.M., Raih M.F.,
RA Bakar F.D., Najimudin N., Mahadi N.M., Illias R.M.;
RT "A comparative genomic analysis of the alkalitolerant soil bacterium
RT Bacillus lehensis G1.";
RL Gene 545:253-261(2014).
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP003923; AIC94815.1; -; Genomic_DNA.
DR RefSeq; WP_038480708.1; NZ_CP003923.1.
DR AlphaFoldDB; A0A060LYG0; -.
DR STRING; 1246626.BleG1_2237; -.
DR KEGG; ble:BleG1_2237; -.
DR PATRIC; fig|1246626.3.peg.2235; -.
DR eggNOG; COG1298; Bacteria.
DR HOGENOM; CLU_015346_3_0_9; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000027142; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:AIC94815.1};
KW Cilium {ECO:0000313|EMBL:AIC94815.1};
KW Flagellum {ECO:0000313|EMBL:AIC94815.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000027142};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 7..24
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 30..49
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 93..119
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 188..210
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 230..252
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 264..284
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 679 AA; 74014 MW; E684A32E0C4F98A5 CRC64;
MKAKDLSILA GVILIIVMLI IPLPPFLLDV LIIFNISLSL LILLVALNTK NALQFSVFPT
MLLLVTLFRL GLSVSTTRSI LGEAHAGNVI DTFGSFVIGG NAVVGFVVFL ILIIIQFLVI
TKGAERVSEV GARFTLDAMP GKQMSIDADL NAGLISDREA KARREKIENE ADFYGSMDGA
SKFVKGDAIA SIIIVIINMV FGLVIGMMQM GMDLSTAAST YTLLTVGDGL VTQIPALLIS
TATGVIVTKA ASEGNLGNDL TKQLLAYPKL LYVTAATIFL LGVTTPITKV VTFSVAGLLA
FAGYRLSKAR TVEEEMEHQL QEETTDVPEP TGPESVLSLM KMDPIEFEFG YGLIPLADAN
QGGDLLDRVV MIRKQMALEL GTMIPVIRIR DNLSLEPNAY TIKIKGDVVA KGEVLLDHYM
AMSTGIEDER ITGIATVEPA FGLEAMWVTE DVKEEAELSG YTVVDPPTVI STHLTELLKT
YAHELLGREE TKALIEHVKE TYPTLVEEVT PTPLSIGDVQ KVLKNLLREQ LSIRNLPMIF
ETLADYGSRT KDMDVVTEYV RQALSRQISE QLTDEQNKLA VITLASEVEK RIADAVGQNE
NGHFLALAPA DSQTILQQTA SETTKLAEMG QQAVILCSPA VRMYMRHLIE RYLPQVPVIS
YNELDASVEV QSVGVVRLQ
//
