ID A0A061E1Y8_THECC Unreviewed; 534 AA.
AC A0A061E1Y8;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=UDP-MurNAc-pentapeptide synthetase {ECO:0000256|ARBA:ARBA00031461};
GN ORFNames=TCM_007674 {ECO:0000313|EMBL:EOX99054.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOX99054.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOX99054.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
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DR EMBL; CM001880; EOX99054.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061E1Y8; -.
DR STRING; 3641.A0A061E1Y8; -.
DR EnsemblPlants; EOX99054; EOX99054; TCM_007674.
DR Gramene; EOX99054; EOX99054; TCM_007674.
DR eggNOG; ENOG502QT6H; Eukaryota.
DR HOGENOM; CLU_031507_1_1_1; -.
DR InParanoid; A0A061E1Y8; -.
DR OMA; IEMGANH; -.
DR Proteomes; UP000026915; Chromosome 2.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0047480; F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR Gene3D; 3.40.1390.10; MurE/MurF, N-terminal domain; 1.
DR HAMAP; MF_02019; MurF; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR InterPro; IPR035911; MurE/MurF_N.
DR InterPro; IPR005863; UDP-N-AcMur_synth.
DR NCBIfam; TIGR01143; murF; 1.
DR PANTHER; PTHR43024; UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE; 1.
DR PANTHER; PTHR43024:SF1; UDP-N-ACETYLMURAMOYL-TRIPEPTIDE--D-ALANYL-D-ALANINE LIGASE; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
DR SUPFAM; SSF63418; MurE/MurF N-terminal domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000026915}.
FT DOMAIN 163..352
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
FT DOMAIN 372..436
FT /note="Mur ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02875"
SQ SEQUENCE 534 AA; 57509 MW; 51965B4458EC31A6 CRC64;
MSAFPFPNTF TLTNSSVSRS LATRLHARVL VSATSIKSTL NHSNHSTQVT PCGPSNSPLW
TVTDIAEAVG GRIVKWGPPG TICTDTRTIE PGQWFFAIVG ENFDAHDFVT PELSECGCVG
VIGNRVCENW DVGFVKIDGD TLISLVKMAT FARNRFLGKL IAVTGSVGKT STKAMIALAL
ESLESRIHHS YGNWNTRIGV ALSLIGIPRN VDIAILEMGM SGKGEILELA RMGRPDIRVI
LNVGPSHLEK LGSLEEVAMA KGELLEEAKP GDVCVLNADD PLVVGLPVPP GVRRVLFGQS
LECDVRLVAA DSICGGLGVR VVLENNMEMV EFVIPGLGLH LALNACAAAA VVTYFGHPLS
QVGRSLSRYV PVNMRSEFVA AKCGIRIVND VYNANPVSTK AAIDTLKSID CNGKRVAIFG
DMLELGPAEM EYHEEILNYC LDAHIDLVGI AGKRFHVAAE NMNLHKKINI IHAVDAENIV
PKILNCLNIN DVVLVKGSRS MQMEKVVDAL KAMHGFTPSP CSGNLDEDKI EDKS
//
