ID   A0A061F0P7_THECC        Unreviewed;       555 AA.
AC   A0A061F0P7;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=3-deoxy-d-manno-octulosonic-acid transferase isoform 1 {ECO:0000313|EMBL:EOY08084.1};
GN   ORFNames=TCM_022399 {ECO:0000313|EMBL:EOY08084.1};
OS   Theobroma cacao (Cacao) (Cocoa).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX   NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY08084.1, ECO:0000313|Proteomes:UP000026915};
RN   [1] {ECO:0000313|EMBL:EOY08084.1, ECO:0000313|Proteomes:UP000026915}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX   PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA   Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA   Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA   Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA   Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA   Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA   Kuhn D.N.;
RT   "The genome sequence of the most widely cultivated cacao type and its use
RT   to identify candidate genes regulating pod color.";
RL   Genome Biol. 14:R53.1-R53.24(2013).
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DR   EMBL; CM001883; EOY08084.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A061F0P7; -.
DR   STRING; 3641.A0A061F0P7; -.
DR   EnsemblPlants; EOY08084; EOY08084; TCM_022399.
DR   Gramene; EOY08084; EOY08084; TCM_022399.
DR   eggNOG; ENOG502QSA5; Eukaryota.
DR   InParanoid; A0A061F0P7; -.
DR   OMA; WFHACSY; -.
DR   Proteomes; UP000026915; Chromosome 5.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0043842; F:Kdo transferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016740; F:transferase activity; IBA:GO_Central.
DR   GO; GO:0009245; P:lipid A biosynthetic process; IBA:GO_Central.
DR   Gene3D; 3.40.50.11720; 3-Deoxy-D-manno-octulosonic-acid transferase, N-terminal domain; 1.
DR   Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 1.
DR   InterPro; IPR007507; Glycos_transf_N.
DR   InterPro; IPR038107; Glycos_transf_N_sf.
DR   InterPro; IPR039901; Kdotransferase.
DR   PANTHER; PTHR42755:SF1; 3-DEOXY-D-MANNO-OCTULOSONIC ACID TRANSFERASE, MITOCHONDRIAL-RELATED; 1.
DR   PANTHER; PTHR42755; 3-DEOXY-MANNO-OCTULOSONATE CYTIDYLYLTRANSFERASE; 1.
DR   Pfam; PF04413; Glycos_transf_N; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EOY08084.1}.
FT   DOMAIN          81..260
FT                   /note="3-deoxy-D-manno-octulosonic-acid transferase N-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04413"
FT   REGION          1..38
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..32
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        108
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR639901-1"
FT   SITE            178
FT                   /note="Transition state stabilizer"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR639901-2"
FT   SITE            258
FT                   /note="Transition state stabilizer"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR639901-2"
SQ   SEQUENCE   555 AA;  61817 MW;  CC95E81B16647A83 CRC64;
     MGPEKPFPAQ SHRAKPKPSK PCFKKRKRSR LPKQAEGKMA MAGSRGELVY KIYRALTYGL
     SPLLHLHLHW RKFRGLEHPL RWPERLGRPS LPRPPGLLLW FHAVSLGEGM AAIPVIKCCS
     QLRPDVNILM TTTTFSAFEV LKNRIPANVI YQFAPIDTPS AMDAFLGYWK PNGIVIMESE
     LWPNLIVGAS KCGIGLALLN ARLSAKSFRN WSRPVLFPLI SLLLSKFSLI VPLSSVQAIH
     FQLLQAPPFS INFSGDLKYA VDECEPLVKD VGRIEDLQKQ LSQKRVWMAA SIHRGEEEIM
     LGVHKGLTQT YPDLVTIIVP RHPQHGKEIA EELQKGGKTV ALRSQHEKLI PGTSIYVVDT
     LGELRQLYKL SPIAVIGGSF FPGLAGHNIS EAAAAGCAVL TGHHVGHFSH MVIEMQQLNP
     LSVMQVSGKL DLEKALGKLF SDAKILESRQ KAAKEAFNAL SSSVVTNAWN LLNFHFLRQL
     TKNWLVQVIC FYDESPASIP NSNSQVTRGD IPGKFPLSGS SKFAPHKVHS FEFHNVTDIT
     FGIICWRSHG MRWAD
//