ID A0A061G342_THECC Unreviewed; 864 AA.
AC A0A061G342;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 43.
DE SubName: Full=Extra-large GTP-binding protein 3 {ECO:0000313|EMBL:EOY21454.1};
GN ORFNames=TCM_013017 {ECO:0000313|EMBL:EOY21454.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY21454.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY21454.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
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DR EMBL; CM001881; EOY21454.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061G342; -.
DR STRING; 3641.A0A061G342; -.
DR EnsemblPlants; EOY21454; EOY21454; TCM_013017.
DR Gramene; EOY21454; EOY21454; TCM_013017.
DR eggNOG; KOG0082; Eukaryota.
DR HOGENOM; CLU_006703_0_0_1; -.
DR InParanoid; A0A061G342; -.
DR OMA; NIWQKAS; -.
DR Proteomes; UP000026915; Chromosome 3.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR CDD; cd00066; G-alpha; 1.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR10218:SF317; EXTRA-LARGE GUANINE NUCLEOTIDE-BINDING PROTEIN 3-LIKE; 1.
DR PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR Pfam; PF00503; G-alpha; 1.
DR PRINTS; PR00318; GPROTEINA.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT DOMAIN 1..23
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 66..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 150..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..113
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 864 AA; 97926 MW; 948E8A06A01CC040 CRC64;
MAASTEAEEE NKAWEDVIRK MLPVGAPLPD EDHLDYSIAV EYEGPPIPYD VPRVDPLDLG
SLAASDLSSI PVAAPIPTKP KFSSFKKNRN NIRNGSPLES QRPSSASRSQ IDSRNGDYDS
EIEVDKSPPP PLPQPQPVTV DKKNVVVTFN TPKDSETEEE EDDGYSSSQS CVADAAASVG
NVETRGIKKK EKKRGICSRC EKGSRLKERE ACLVCDARYC SNCLLKAMGS MPEGRKCVGC
IGKPIDEAKR SRLGKSSRIL RTVCSALEVK QIMKAEKECA ANQLRPEQLV VNGRQLTPEE
LAEVLGCPLP PQKLKPGKYW YDKDSGLWGK EGEKPDRIIS SKLNIGGKMK KDASNGNTRV
YINGREITKI ELRVLKLANV QCPRDTHFWM YDDGSYEEEG QNNIKGKIWE KASTRFFCSL
FSLPVPPANP HGPQEDPTTF SGRSVPEYLE QGRVQKLLLF GLEGSGTSTI FKQAKLLYGN
GFSPEELQSI KLMIQSNMYK YLSVLLEGRE RFEEEALLAL RTTNFDTEES ASGETVVDGS
NQCIYSINQR FKHFSDWLLD IMAMGDLDTF FPAATREYAP IVDEIWKDPA IQETYKRSEE
LHHLPDVAKY FLDQAVEISS NEYEPSERDI LYAEGVTQSN GLALIEFSFD DRSPMSEIYN
ENFECPPSLT KYQLIRINSK GLHDGCKWLE MFEDVRAVIF CVALSDYDEI WCRGTDPLCN
KMLASRDMFE SLVRHPSFRE TPFVLLLNKY DAFEDKINRV PLSTCEWFRD FSPLKPHHNN
HALAQQAYYY MAVKFKELYF SISGRKLFVS QTRARERASI DEAFKYIREV LKWDEEKDDN
VYGINGDDSF YSTEMSSSPY IRHE
//
