ID A0A061GIB0_THECC Unreviewed; 979 AA.
AC A0A061GIB0;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=TCM_036854 {ECO:0000313|EMBL:EOY29261.1};
OS Theobroma cacao (Cacao) (Cocoa).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Malvales; Malvaceae; Byttnerioideae; Theobroma.
OX NCBI_TaxID=3641 {ECO:0000313|EMBL:EOY29261.1, ECO:0000313|Proteomes:UP000026915};
RN [1] {ECO:0000313|EMBL:EOY29261.1, ECO:0000313|Proteomes:UP000026915}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Matina 1-6 {ECO:0000313|Proteomes:UP000026915};
RX PubMed=23731509; DOI=10.1186/gb-2013-14-6-r53;
RA Motamayor J.C., Mockaitis K., Schmutz J., Haiminen N., Iii D.L.,
RA Cornejo O., Findley S.D., Zheng P., Utro F., Royaert S., Saski C.,
RA Jenkins J., Podicheti R., Zhao M., Scheffler B.E., Stack J.C., Feltus F.A.,
RA Mustiga G.M., Amores F., Phillips W., Marelli J.P., May G.D., Shapiro H.,
RA Ma J., Bustamante C.D., Schnell R.J., Main D., Gilbert D., Parida L.,
RA Kuhn D.N.;
RT "The genome sequence of the most widely cultivated cacao type and its use
RT to identify candidate genes regulating pod color.";
RL Genome Biol. 14:R53.1-R53.24(2013).
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CM001887; EOY29261.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061GIB0; -.
DR EnsemblPlants; EOY29261; EOY29261; TCM_036854.
DR Gramene; EOY29261; EOY29261; TCM_036854.
DR eggNOG; KOG1052; Eukaryota.
DR HOGENOM; CLU_007358_0_2_1; -.
DR InParanoid; A0A061GIB0; -.
DR OMA; TSANIWQ; -.
DR Proteomes; UP000026915; Chromosome 9.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF450; GLUTAMATE RECEPTOR 2.8-RELATED; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000026915};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..979
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001599178"
FT TRANSMEM 591..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 650..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 834..857
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 464..813
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT REGION 904..930
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 949..979
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 950..972
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 761..817
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 979 AA; 108395 MW; B100756E8527B84D CRC64;
MMRSSTEHML FHLFCVFIFL LEGVLTQNST TQVKVGVVLD LDTPAGKIGL SCINMALSDF
YETHAHYKTR LVLNVRDSKE DVVAAADAAL DLMKNVQVQA IIGPRSSMQA NFVINLGNES
KVPIISFSAT SPSLTSLQSP YFFLAAQSSS NQVKAISAIV QAFGWKEAVP IYVDNQSGES
LIPYLTDALQ EINARVPYLS IIAAAATDDQ IAEELYKLMT MQTRLFIVHM TMSLGSRILA
KAKEIGMMSE GYVWIMTDVM TNLWRSIDAS PIDSMQGVVG VKSYVAKSKK IENFTVRWKR
KFQQENPDSI NAELSIVGLW AYDATFALAM AIEKAGTENL RFNKPTISSS GATDLETLGV
SQNGPRLIRE LSSKKFKGLS GDFHFVKGQL QSSVFQIVNV IGSGEKEVGF WTPENGLVRQ
LDSTNTNAST NSTSKPKLGP IIWPGETNLV PKGWQIPTNG KKLRIGVPVK VGFTEFLNVV
WDPIAQKAKS IEGYCIDVFD AVMDKMPYAV PYEYVPFATT DGKAAGSYND LTDQVYYGNY
DAVVGDTTIV ANRSLFVDFA LPFTESGVSM IVPIRDNKEK NAWVFLKPLT WDLWVTSGCF
FVFIGFVVWI LEHRINEDFR GPPAHQIGTS FWFSFSTMVF AHREKVVSNL ARFVVIVWCF
VVLVLTQSYT ANLTSLLTVE QLQPTVTDIN ELVKRRESVG LLNGSFVEGI LLGLKFENFQ
LKIYNSPEEL HELFTKGSAN GGISAALDEN PYIKLFLSKY CGKYTTVEPT FKTAGFGFAF
PKGSPLVADV SRAILNVTQS DKMEQIENFW LKKGTVCPDV DPSVSSSSLG LESFWGLFLI
AGTASMSALI IYSAMFLHEQ RHVLFQFHDT SVWRRIRIMS RIFDQKDLSS HTFRKSEVRD
ASSTHSVHSI GVVGSSPNTN CPPSPSSYSS QTHSSQFVFF VDQGRFTGHG DLTPSGSASP
ETFPSPERSS IELANRNDP
//
