ID A0A061J1B1_TRYRA Unreviewed; 627 AA.
AC A0A061J1B1;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 22-FEB-2023, entry version 20.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 {ECO:0000256|ARBA:ARBA00021776};
GN ORFNames=TRSC58_04380 {ECO:0000313|EMBL:ESL07926.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL07926.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL07926.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL07926.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Essential factor for the assembly of mitochondrial
CC NADH:ubiquinone oxidoreductase complex (complex I).
CC {ECO:0000256|ARBA:ARBA00004069}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004370}.
CC Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00004273}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL07926.1}.
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DR EMBL; AUPL01004380; ESL07926.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J1B1; -.
DR EnsemblProtists; ESL07926; ESL07926; TRSC58_04380.
DR VEuPathDB; TriTrypDB:TRSC58_04380; -.
DR OrthoDB; 166834at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0032981; P:mitochondrial respiratory chain complex I assembly; IEA:InterPro.
DR CDD; cd05125; Mth938_2P1-like; 1.
DR Gene3D; 3.40.1230.10; MTH938-like; 1.
DR InterPro; IPR036748; MTH938-like_sf.
DR InterPro; IPR034095; NDUF3.
DR InterPro; IPR007523; NDUFAF3/AAMDC.
DR PANTHER; PTHR21192:SF2; NADH DEHYDROGENASE [UBIQUINONE] 1 ALPHA SUBCOMPLEX ASSEMBLY FACTOR 3; 1.
DR PANTHER; PTHR21192; NUCLEAR PROTEIN E3-3; 1.
DR Pfam; PF04430; DUF498; 1.
DR SUPFAM; SSF64076; MTH938-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737}.
FT REGION 165..193
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 426..450
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..183
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 627 AA; 72290 MW; 6A23DBE729EFFADC CRC64;
MRRSLLRCAG STVDWRTRAR RGVQRFVRRY VPDPRDDPLT ETPMNAEAYK RTHLQQEGGV
RVGIRPGQSI EDYMAERDCK WLAEQQRTTE RLVAEQRLPT TSDGQLFSGA GTRASYMDVE
SANRLVKTPT PTDYEADEEL VLMRRQLQVE NEAEYRRFAA EQKRAELATA ETQKRRRPHP
SDPGYDPFRI TPGYRPQDSV ALAQWLKRQR ESGKTASGLS LQTKEGQERY YNEEKMATQF
HANPFSARVE EPRGISKMRV TAYSPDSIFV NDKEVIGSCI VTDKAYYHWN VSSFEEVNER
TLALLLHLYP VPDVVFLGTG RNLHFIDEDL RIAFQKRGSV IHCLTTPQAC GHFGVQLSVS
RRAALAVINP IPTNGYGVEC FGDFVENDMF SLSDTQLGIP PIKQFSATMF RQNKVAEKYR
HMQGTGFGPK YHQMSDGRLV RPGTSGTKLR PLLEPGEEVQ WETLPSYYHW YPKEHLHDYI
ENTTMREIQG KPTGDPTERR MYQAMRGGKS DKENAPAPDV MPWDSASIPI TKFPHERDEE
EIVVEDPKTG RIIGMDRNTY ERWRVMMQER REGKPESDPV EYDQERFVTN KDGVVFDLSK
MKYRPIFEGR WNPRRPQSTG RTNPIMT
//
