ID A0A061J5G7_TRYRA Unreviewed; 737 AA.
AC A0A061J5G7;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=TRSC58_01589 {ECO:0000313|EMBL:ESL10673.1};
OS Trypanosoma rangeli SC58.
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma; Herpetosoma.
OX NCBI_TaxID=429131 {ECO:0000313|EMBL:ESL10673.1, ECO:0000313|Proteomes:UP000031737};
RN [1] {ECO:0000313|EMBL:ESL10673.1, ECO:0000313|Proteomes:UP000031737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC58 {ECO:0000313|EMBL:ESL10673.1,
RC ECO:0000313|Proteomes:UP000031737};
RA Stoco P.H., Wagner G., Gerber A., Zaha A., Thompson C., Bartholomeu D.C.,
RA Luckemeyer D.D., Bahia D., Loreto E., Prestes E.B., Lima F.M.,
RA Rodrigues-Luiz G., Vallejo G.A., Filho J.F., Monteiro K.M., Tyler K.M.,
RA de Almeida L.G., Ortiz M.F., Siervo M.A., de Moraes M.H., Cunha O.L.,
RA Mendonca-Neto R., Silva R., Teixeira S.M., Murta S.M., Sincero T.C.,
RA Mendes T.A., Urmenyi T.P., Silva V.G., da Rocha W.D., Andersson B.,
RA Romanha A.J., Steindel M., de Vasconcelos A.T., Grisard E.C.;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESL10673.1}.
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DR EMBL; AUPL01001589; ESL10673.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A061J5G7; -.
DR EnsemblProtists; ESL10673; ESL10673; TRSC58_01589.
DR VEuPathDB; TriTrypDB:TRSC58_01589; -.
DR OrthoDB; 131829at2759; -.
DR Proteomes; UP000031737; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.50.7.10; GroEL; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR002423; Cpn60/GroEL/TCP-1.
DR InterPro; IPR027409; GroEL-like_apical_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45748; 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED; 1.
DR PANTHER; PTHR45748:SF7; 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED; 1.
DR Pfam; PF00118; Cpn60_TCP1; 1.
DR Pfam; PF01363; FYVE; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52029; GroEL apical domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000031737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 29..102
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 134..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 592..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 704..737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 608..622
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 82121 MW; D0B9A838ACF531A6 CRC64;
MDMQQEQTER SWGGQGRNVT LRQALWVDDR YAVRCRGCDV RFNVMRRRHH CRNCGQVFCG
ECLITSSTSR LGDIITGVFS SLVGLHRDPL VKLCHKCNCL LQERGMGQRR GWRRVLPPQR
GLLEVSTAAN AATVTHEGGR GGELRPNTAA TTTADAAPVE ANTRMELPRP LEGNLDKRPA
SAPSLTEDQV KSFSGTVPSG VLPQPWQHCL PTHPEDVSEQ EISCGLTDTP MYSRNSVADG
VAKLFKKIRN WKTKQSPEQS QIVCLSRTYT PHPKATFRRA DVGLWSRYFA TVFSHSISKS
SLQRLEAQCS YHLIKRASRL FMKEEALATS SGETAGMDRV EWIAGLCDIS WRVVSQLSVA
LHERIDQRLE VICIPGGQFA DTEIVTGVAF IQNIAFKRMK TLVTSPRLLL LAGDVGTTPS
PRTDLLEYVE GYEGHLDTQY QRIHIWRPSV IVVEGNMHHY LQDKILCQSD ATLILHVGNT
ILQRLSRCCK ASIISDLQYI GASDLYDDSV LGTCESFQVV HHGDRPVCIF KAPQVALFTA
VLLRGADEHR LTIVKELLLN CAATAYHLAL QAHCMFDLGV RCAELHPIPV SVTRGSDSSS
GGRAEGSTEE EAEEDEEKEE DYAPAAWGEA SSADSRQCGA YMQFVTHSPR AEDRLETLSM
NTGVAFPHEV LSFNEKYDDL MVDNIIVNTV FLEYVAGGLS RRRDRWRRGG SPQLQCSPVP
RGPSRSTRKG MRHCWNS
//
