ID A0A066X464_COLSU Unreviewed; 858 AA.
AC A0A066X464;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=RhoGAP domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=CSUB01_01010 {ECO:0000313|EMBL:KDN62479.1};
OS Colletotrichum sublineola (Sorghum anthracnose fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum graminicola species complex.
OX NCBI_TaxID=1173701 {ECO:0000313|EMBL:KDN62479.1, ECO:0000313|Proteomes:UP000027238};
RN [1] {ECO:0000313|Proteomes:UP000027238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TX430BB {ECO:0000313|Proteomes:UP000027238};
RX PubMed=24926053; DOI=10.1128/genomeA.00540-14;
RA Baroncelli R., Sanz-Martin J.M., Rech G.E., Sukno S.A., Thon M.R.;
RT "Draft genome sequence of Colletotrichum sublineola, a destructive pathogen
RT of cultivated sorghum.";
RL Genome Announc. 2:E0054014-E0054014(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDN62479.1}.
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DR EMBL; JMSE01001325; KDN62479.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A066X464; -.
DR STRING; 1173701.A0A066X464; -.
DR eggNOG; ENOG502QQWB; Eukaryota.
DR HOGENOM; CLU_008201_1_0_1; -.
DR OMA; WSQKQPE; -.
DR OrthoDB; 1328399at2759; -.
DR Proteomes; UP000027238; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd04436; DEP_fRgd2; 1.
DR CDD; cd04399; RhoGAP_fRGD2; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 2.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR000591; DEP_dom.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR PANTHER; PTHR23065:SF17; RHO-GTPASE-ACTIVATING PROTEIN RGD2; 1.
DR Pfam; PF00610; DEP; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00049; DEP; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50186; DEP; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Reference proteome {ECO:0000313|Proteomes:UP000027238};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 2..435
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 216..293
FT /note="DEP"
FT /evidence="ECO:0000259|PROSITE:PS50186"
FT DOMAIN 469..666
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 163..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..858
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 736..750
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..784
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 858 AA; 95787 MW; 7E30E1529DA25835 CRC64;
MPGFADSFWS SDYAAGLGVL FSKLQQGVQE NRQVLTIARM RAEAEEIYSQ RLGDIAPTAD
KVQGGFSKDD GASVRKAFDG VRTEMEEGAK NHKKIAQNIR DLVVNPFSRW CDAHESRIQD
SQDELQARIK AHDRQAELVK KLRSTYFNKC RLVEDIEEET KLAFQDPESS PKNIPEIKVS
ENKEPELHPQ EDDDEPIEIG DEIYQPEQVK KILAHMLNTI KLGETKVPIL GTYQNTSAGS
DIVEYLQRHM NTTSISYAER IGQDLISNGY LRLIGNVGNT FANSSKMFYQ WRPKAFKLAG
VPDKKAPLGR TFSLPASEST DSPVVGTVSE YLANWNVLNN QHPNETPPER LRREAREADD
KYKAGVRKLD EMRCELEETI FVHLRFLERC ELDRLKAIKT VILDFSGTIS NVIPSMQSAV
DNMMLFQETV QPLGDLRYLL ESYRTGSFVP KVVVYENYYN KVDEQTFGVD LEARARADKK
RVPVIVTTIL TYLDNRYPDL EGDEARRGVW LVDVPLQQVH KLRNKVNDGK PISPDVFDEF
DIPTVASLLK LYLLELPDSL VSSHVYEIVR TIYQTQSQES DASRVSVLQQ TLSQMRLTNI
ATLDACMNHF TRLIDLTSAD EAYISTLATT IAPCVLRPRT ETSLTMEEKH AYRLVRDLFA
HKEAIFSELK RMSTANHGGS LNRPRAISTD ESNRRANMEE RNRALLEKAA GSRGRATSPA
PSPRGHRRDR STGGPETRFP IQTSPPASAV DRHRSSLGSV VGAKRSSLEV PGSETGSPKE
MTATNGSAAP AAEGVAARIK ALESPGEKRN SLSRSSVRYS LDRHVAAAPS AGTESGSSTP
RDSGAPRGVT LEDKPMDD
//
