ID A0A066Z3C2_9ACTN Unreviewed; 383 AA.
AC A0A066Z3C2;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:KDN84856.1};
DE EC=2.7.13.3 {ECO:0000313|EMBL:KDN84856.1};
GN ORFNames=KCH_33830 {ECO:0000313|EMBL:KDN84856.1};
OS Kitasatospora cheerisanensis KCTC 2395.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Kitasatospora.
OX NCBI_TaxID=1348663 {ECO:0000313|EMBL:KDN84856.1, ECO:0000313|Proteomes:UP000027178};
RN [1] {ECO:0000313|EMBL:KDN84856.1, ECO:0000313|Proteomes:UP000027178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 2395 {ECO:0000313|EMBL:KDN84856.1,
RC ECO:0000313|Proteomes:UP000027178};
RA Nam D.H.;
RT "Draft Genome Sequence of Kitasatospora cheerisanensis KCTC 2395.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KDN84856.1}.
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DR EMBL; JNBY01000089; KDN84856.1; -; Genomic_DNA.
DR RefSeq; WP_035863625.1; NZ_KK853997.1.
DR AlphaFoldDB; A0A066Z3C2; -.
DR PATRIC; fig|1348663.4.peg.3255; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_000445_20_2_11; -.
DR OrthoDB; 5242012at2; -.
DR Proteomes; UP000027178; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR025828; Put_sensor_dom.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF13796; Sensor; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KDN84856.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027178};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KDN84856.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 23..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 46..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 23..137
FT /note="Putative sensor"
FT /evidence="ECO:0000259|Pfam:PF13796"
FT DOMAIN 187..252
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT DOMAIN 296..376
FT /note="Histidine kinase/HSP90-like ATPase"
FT /evidence="ECO:0000259|Pfam:PF02518"
SQ SEQUENCE 383 AA; 40492 MW; 74F72A7458086F27 CRC64;
MEDEAKRPSL YGAQLWQRVQ HELLNFPIGL AGFVAASVLL TAGLGLAVTF VGLPLLAVGL
VCCRGFGRLG RVRARASLGS RIAEPEPTVP SRPGPAGWVV AALSDGLNWR SALYCVVMLP
WGILSFVLTL VLLVVGWPVL PWAMRAISAV SRLLVEGLLS PGALAERVRE LEDDRGAVVD
HAAADLRRIE RDLHDGAQAR LVALAMDLGL AKEKLTEDPV AAQKMVDAAH GEVKLALQEL
RDLARGIHPA VLTDRGLDAA LSSVAARCTL PGGVKVHVEL GGERPDSAVE GIAYFTVSEL
LTNASKHSGA RSASVDVWRQ DDRLMLTVQD DGRGGARVRP GGGLAGLAER AESVDGVFVV
DSPAAGPTSV TVELPWRTRA ARG
//
