ID   A0A067BRZ7_SAPPC        Unreviewed;       481 AA.
AC   A0A067BRZ7;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=PI3K/PI4K catalytic domain-containing protein {ECO:0000259|Pfam:PF00454};
GN   ORFNames=SPRG_13961 {ECO:0000313|EMBL:KDO21033.1};
OS   Saprolegnia parasitica (strain CBS 223.65).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC   Saprolegnia.
OX   NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO21033.1, ECO:0000313|Proteomes:UP000030745};
RN   [1] {ECO:0000313|EMBL:KDO21033.1, ECO:0000313|Proteomes:UP000030745}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO21033.1,
RC   ECO:0000313|Proteomes:UP000030745};
RX   PubMed=23785293;
RA   Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA   van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA   Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA   Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA   Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA   Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA   Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA   Russ C., Tyler B.M., van West P.;
RT   "Distinctive expansion of potential virulence genes in the genome of the
RT   oomycete fish pathogen Saprolegnia parasitica.";
RL   PLoS Genet. 9:E1003272-E1003272(2013).
CC   -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type II PI4K
CC       subfamily. {ECO:0000256|ARBA:ARBA00008941}.
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DR   EMBL; KK583297; KDO21033.1; -; Genomic_DNA.
DR   RefSeq; XP_012208285.1; XM_012352895.1.
DR   AlphaFoldDB; A0A067BRZ7; -.
DR   EnsemblProtists; KDO21033; KDO21033; SPRG_13961.
DR   GeneID; 24135797; -.
DR   KEGG; spar:SPRG_13961; -.
DR   VEuPathDB; FungiDB:SPRG_13961; -.
DR   OMA; HMANCKL; -.
DR   OrthoDB; 68152at2759; -.
DR   Proteomes; UP000030745; Unassembled WGS sequence.
DR   InterPro; IPR044571; P4KG1-8.
DR   InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR   PANTHER; PTHR45800; PHOSPHATIDYLINOSITOL 4-KINASE GAMMA; 1.
DR   PANTHER; PTHR45800:SF11; PI3K_PI4K CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030745}.
FT   DOMAIN          200..399
FT                   /note="PI3K/PI4K catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF00454"
SQ   SEQUENCE   481 AA;  52649 MW;  EDCDCE7AA5BB41D0 CRC64;
     MVTSTYLRGV FHLRRPDASR LPPKPVKSQA LDLDQNPKRE DVVLHLERDS LQEELAVFVN
     QRQLTSLRIP LPRHWTMDHR ASLDAIAASV HGLTVAVDDD ALVASLPNTN DAPEVFVNVP
     ELAAKGRDSF VAHLRHDRMD SAGGHRVHML WDVAQLQSTN AHAFESVVGG EGGVYALSSS
     TSGAKVVMFK PIEEEVFVRE GLCAGEGAVR EEAAYVLDAA MGGFSGVPPT AVARLHMANC
     KLKKPSGTNN SGWFKLGAVQ RFMAPSAGSM EDFGMPHALE KAVQMASVDQ VHRVGLLDVR
     LFNTDRHGGN LLLLGKTAPY KLVPIDHGCI LPSWDRLSEA RLDWATYPQA QAPFSPAMRQ
     HVAALNASAD AHRLRRLGIR EECIATLYIC TLVLKTATLA GKSLAWIGAY LSRDGCFEAP
     SRLEEAIARA CTACDIPYLW TKNDHGEARF DVTDGILRRR PPNIFYTCLQ KAVTLDVTAT
     K
//