ID A0A067CD30_SAPPC Unreviewed; 1495 AA.
AC A0A067CD30;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Myosin motor domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SPRG_20866 {ECO:0000313|EMBL:KDO24461.1};
OS Saprolegnia parasitica (strain CBS 223.65).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Saprolegniales; Saprolegniaceae;
OC Saprolegnia.
OX NCBI_TaxID=695850 {ECO:0000313|EMBL:KDO24461.1, ECO:0000313|Proteomes:UP000030745};
RN [1] {ECO:0000313|EMBL:KDO24461.1, ECO:0000313|Proteomes:UP000030745}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 223.65 {ECO:0000313|EMBL:KDO24461.1,
RC ECO:0000313|Proteomes:UP000030745};
RX PubMed=23785293;
RA Jiang R.H., de Bruijn I., Haas B.J., Belmonte R., Lobach L., Christie J.,
RA van den Ackerveken G., Bottin A., Bulone V., Diaz-Moreno S.M., Dumas B.,
RA Fan L., Gaulin E., Govers F., Grenville-Briggs L.J., Horner N.R.,
RA Levin J.Z., Mammella M., Meijer H.J., Morris P., Nusbaum C., Oome S.,
RA Phillips A.J., van Rooyen D., Rzeszutek E., Saraiva M., Secombes C.J.,
RA Seidl M.F., Snel B., Stassen J.H., Sykes S., Tripathy S., van den Berg H.,
RA Vega-Arreguin J.C., Wawra S., Young S.K., Zeng Q., Dieguez-Uribeondo J.,
RA Russ C., Tyler B.M., van West P.;
RT "Distinctive expansion of potential virulence genes in the genome of the
RT oomycete fish pathogen Saprolegnia parasitica.";
RL PLoS Genet. 9:E1003272-E1003272(2013).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KK583242; KDO24461.1; -; Genomic_DNA.
DR RefSeq; XP_012204897.1; XM_012349507.1.
DR STRING; 695850.A0A067CD30; -.
DR EnsemblProtists; KDO24461; KDO24461; SPRG_20866.
DR GeneID; 24141867; -.
DR KEGG; spar:SPRG_20866; -.
DR VEuPathDB; FungiDB:SPRG_20866; -.
DR OMA; DEYTEYV; -.
DR OrthoDB; 72150at2759; -.
DR Proteomes; UP000030745; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd14891; MYSc_Myo30; 1.
DR CDD; cd06093; PX_domain; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF845; MYOSIN MOTOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00612; IQ; 2.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF00787; PX; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00015; IQ; 3.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00312; PX; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR PROSITE; PS50096; IQ; 3.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50195; PX; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000030745}.
FT DOMAIN 118..812
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1240..1371
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 688..710
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT BINDING 212..219
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1495 AA; 168159 MW; 0D14394948CED694 CRC64;
MAHIKPAAAL PSHERFQARA PTDMSNLSIN QRLVMENKKR SAALRRRNTI EVEKMLSAAP
VEVGAQIWLP DPETVWRIVE IVKYHEEEKG MILTVVGPRG QETVDMRDIG DLYRVNPRVV
DDMTSLYYIH EAGILENLNV RSRLDNQRPY TFMANVLIAV NPLRKVVEPH IKDYVKTQMG
DRPPHPYAVA EVAFQQMSLR SPSQCQSIVI SGESGAGKTE TSKIVLRYIT TREHILSSDV
APISTSKLSS QELDRRLWDT NPILEAFGNA KTLRNHNSSR FGKFMKLQFS EVAGNRLHLM
GAFIETYLLE KFRVVAQIPH ERNFHIFYFL LAGASDELSA KLSLGSPKDF FYLNQSGCVS
DPNIDDELLF DDVCSALKTV GVDADKQLSV WTLLAGILHL GNVVLVNRET SEGDCAEVSS
NTTPALATCA MHLGVDGAHL ERVITQREIE TRGEKFVIKR NAKEGSYVRD AIVKSIYQHL
FDWIVQHINV ALGHGPPELP FIGVLDIFGF ESFAVNDFEQ LLINYANEAL QATFNQQVFI
AEQELFLHEG IDVGKIQWPD NRDCIDLIAA KPNGILALLD AEARTQKPSD DKWNATLHKT
HAGHAHFLAP HEKDKKFVFL IKHFATMVPY TIGNFIDKNN DTIPKDLEDL VLSSTSALMA
QIYKDGADLS AGSSLKKPSV SNKFCDQMHA LVDTLNATRC NFIRCVKPNP TMALGVFDNG
YVVDQLRCTG MLATCELLKV GLPTRVSYDE ICRIYKPVLP PNVTPMFACY NERTFTEAVL
WAFRVDNDAY RLGRTRVFFK TGKIALLDAL LKVDMKKMGP WIVARLKKWL ARRRWRYATA
KILAQRAFLW LLEQTRKRKA AILKMQSIVR MYNVRKQFLQ SRTRHREAAK RKLAAQHRWK
IAIAHVRGRV AFIELFANSR AKLAAQQARI NRAAVVLQSI ARGKLARREA DRLRRLAQDA
AMRARLAQEA RARAEESKKT AKKRWHAAFY TIMAQRHFVQ RLVKIRNARM AAEKAQARQR
EEMEARRQVE AAEHARMAYL QSQSALKIQA AYRGKVGRDE ARRVAAVVYA QRAAEAAVLA
ADEAARAAEI ASEAHQAEAA ALRKLDSLEA TRHATMGSVG LASAGVMGTA GVHGVAGEAS
AMGAMGSQGV AGAVMGHQES LHEPDLSWMP QDAPIVSETT VGDAMRAEQL AQAGRDLFGE
EGAEVVGPLE SAEDDNMRNP VERFQEFPTG PPIPYKGGIF TCTLLGHRKL QDENWGDEYT
EYVLRVTWGR DILEQSKTAW LVGGRYNDFN SLHQELKAAA SGKRGKRAPW FPRFPKRHPF
SSLIGKNQEE KFIIKREKEL NRYMTQVLTQ MPDALLNVHM DRFLQLTLRT SDICEREAFA
EARKAWEEEE RQAIANAADA EPLNDAELHE VEQLVHELLE KVMYSQGDIR NDNGLQEMIH
AVKVLQPRVT ASAQIGAGVN MELVPLAMQL QDDIQDAFSQ YNDTLLALRL DQDFH
//
