ID   A0A067E9C9_CITSI        Unreviewed;      1103 AA.
AC   A0A067E9C9;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=MMS19 nucleotide excision repair protein {ECO:0000256|RuleBase:RU367072};
GN   ORFNames=CISIN_1g001284mg {ECO:0000313|EMBL:KDO51789.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO51789.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO51789.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key component of the cytosolic iron-sulfur protein assembly
CC       (CIA) complex, a multiprotein complex that mediates the incorporation
CC       of iron-sulfur cluster into apoproteins specifically involved in DNA
CC       metabolism and genomic integrity. In the CIA complex, MMS19 acts as an
CC       adapter between early-acting CIA components and a subset of cellular
CC       target iron-sulfur proteins. {ECO:0000256|RuleBase:RU367072}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|RuleBase:RU367072}.
CC   -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC       {ECO:0000256|ARBA:ARBA00009340, ECO:0000256|RuleBase:RU367072}.
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DR   EMBL; KK785047; KDO51789.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A067E9C9; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0097361; C:CIA complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-UniRule.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   GO; GO:0097428; P:protein maturation by iron-sulfur cluster transfer; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR039920; MET18/MMS19.
DR   InterPro; IPR024687; MMS19_C.
DR   InterPro; IPR029240; MMS19_N.
DR   PANTHER; PTHR12891; DNA REPAIR/TRANSCRIPTION PROTEIN MET18/MMS19; 1.
DR   PANTHER; PTHR12891:SF0; MMS19 NUCLEOTIDE EXCISION REPAIR PROTEIN HOMOLOG; 1.
DR   Pfam; PF12460; MMS19_C; 1.
DR   Pfam; PF14500; MMS19_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   DNA damage {ECO:0000256|RuleBase:RU367072};
KW   DNA repair {ECO:0000256|RuleBase:RU367072};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU367072};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          1..264
FT                   /note="MMS19 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF14500"
FT   DOMAIN          641..1051
FT                   /note="MMS19 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12460"
SQ   SEQUENCE   1103 AA;  121703 MW;  2A6780DDE8B95B8F CRC64;
     MGMYLTTTDD VIRARGILLL GELLTHLASK PLDDATIHSM LAFFTDRLAD WKALRGALVG
     CLALLRRKSS GGVITTNDAK AVAQSYIQNL QVQSLAQHDR KLCFELLECL LQRYPDAVVS
     LGEDLLYAIC EAIDGEKDPH CLMLTFHIVE VAAELFSDDL LANFASDLFE ILGCYFPIHF
     THSKAEDFDV KRDDLSRALM AAFSSTSLFE PFAIPLLLEK LSSSLQSAKV DSLKYLSHCT
     VKYGADRIEK HAKAMWSSIK DAIYSSHEPT LSFASESLDG VGFRDNVILT ESLNLLDTVF
     KQNSGLFLSW IIGDEDINLI FKSISSFKTY KEISLQSKQK LHAVGSILSV SAKASPAACN
     SVMESFFPCL MHPLGLSVGN STQDCFPNDG NVLRGKLNHG ALYLCIELMT ACRELMASSE
     EFKSVAAPAN ERWYCLLQSY SASLAKALRS TLETSANEDS YETNVYFGVK GLLILGTFSG
     GSLIISNSIF ENILLTFTSI IISEFENTLL WKLALKALVH IGSFIDRFNE SEKALSYMDV
     VIEKIVSLAS SHDFSMPFPL KLEAISEIGA TGRNYLLKIV QGLEEAVCAN LYEVLVHGNP
     KSAEVVVQLL ECYSNKVLPR IHEIGGFEEV LLRFAVNIWN LIEKSVTFSS QVHEKGLLDA
     TMKAMKLAVG SCSVESQNIV FQKAFTVLSL GTYFPLEDAA SNIPILLNEF QLTQETSISS
     SREAWICSLF ASVIIAARPQ THIPNVRLVI RLFMTTLLKG NVPAAQALGS MVNKLGLKSN
     GTEVHGNCTL EEAMDIIFDS KLWSFNDSVT LRSNGGLENG SSIGLTDICR GATNIRSLQV
     HAIAGLAWIG KGLLMRGHEK VKDITMTFIE CLLSNSKLGS FSLEQDYSEN SSESVVKYAA
     DAFKILMGDS EDCLSRKLHA TIRPLYKQRF YSTIMPILQS LIIKSNSSFS RSILCRACAH
     IISDTPLIVV LNDAKTVIPI LMDGLSILSN DVSDKDIVYS LLLVLSGILT DKNGQEAVIE
     CAHIIIDHSI ILISYPHMML VRETAIQCLV AMSKLPHARI YPMRREVLQA ISRALDDPKR
     AVRQEAVRCR QAWASTASRS LYF
//