ID   A0A067EH64_CITSI        Unreviewed;      1114 AA.
AC   A0A067EH64;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=TOG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CISIN_1g001249mg {ECO:0000313|EMBL:KDO54433.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO54433.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO54433.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KK784995; KDO54433.1; -; Genomic_DNA.
DR   RefSeq; XP_006488928.1; XM_006488865.2.
DR   AlphaFoldDB; A0A067EH64; -.
DR   STRING; 2711.A0A067EH64; -.
DR   PaxDb; 2711-XP_006488928-1; -.
DR   GeneID; 102619446; -.
DR   KEGG; cit:102619446; -.
DR   eggNOG; KOG2171; Eukaryota.
DR   OrthoDB; 24319at2759; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IBA:GO_Central.
DR   GO; GO:0008139; F:nuclear localization sequence binding; IBA:GO_Central.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR021133; HEAT_type_2.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   InterPro; IPR041653; Importin_rep_4.
DR   InterPro; IPR041389; Importin_rep_6.
DR   InterPro; IPR034085; TOG.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR   Pfam; PF13513; HEAT_EZ; 3.
DR   Pfam; PF18808; Importin_rep_4; 1.
DR   Pfam; PF18829; Importin_rep_6; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SMART; SM01349; TOG; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50077; HEAT_REPEAT; 2.
PE   4: Predicted;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          40..114
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00913"
FT   DOMAIN          368..605
FT                   /note="TOG"
FT                   /evidence="ECO:0000259|SMART:SM01349"
FT   REPEAT          419..457
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT   REPEAT          924..956
FT                   /note="HEAT"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
SQ   SEQUENCE   1114 AA;  123484 MW;  7D739A38BD4B6AF9 CRC64;
     MAAESTHLQQ SQLAVILGPD SAPFETLISH LMSTSNEQRS EAELLFNLCK QQDPDSLTLK
     LAHLLQRSPH PEARAMAAVL LRKLLTRDDS FLWPRLSLHT QSSLKSMLLQ SIQLESAKSI
     SKKLCDTVSE LASNILPENG WPELLPFMFQ CVSSDSVKLQ ESAFLIFAQL SQYIGDTLTP
     HLKHLHAVFL NCLTNSNNPD VKIAALNAVI NFIQCLTSSA DRDRFQDLLP LMMRTLTESL
     NNGNEATAQE ALELLIELAG TEPRFLRRQL VDVVGSMLQI AEAESLEEGT RHLAIEFVIT
     LAEARERAPG MMRKLPQFIN RLFAILMSML LDIEDDPLWH SAETEDEDAG ESSNYSVGQE
     CLDRLAIALG GNTIVPVASE QLPAYLAAPE WQKHHAALIA LAQIAEGCAK VMVKNLEQVL
     SMVLNSFRDP HPRVRWAAIN AIGQLSTDLG PDLQNQFHPQ VLPALAGAMD DFQNPRVQAH
     AASAVLNFSE NCTPEILTPY LDGIVSKLLV LLQNGKQMVQ EGALTALASV ADSSQEHFQK
     YYDAVMPFLK AILVNATDKS NRMLRAKSME CISLVGMAVG KDKFRDDAKQ VMEVLMSLQG
     SQMETDDPTT SYMLQAWARL CKCLGQDFLP YMSVVMPPLL QSAQLKPDVT ITSADSDNEI
     EDSDDDSMET ITLGDKRIGI KTSVLEEKAT ACNMLCCYAD ELKEGFFPWI DQVAPTLVPL
     LKFYFHEEVR KAAVSAMPEL LRSAKLAIEK GLAPGRNESY VKQLSDFIIP ALVEALHKEP
     DTEICASMLD SLNECIQISG PLLDEGQVRS IVDEIKQVIT ASSSRKRERA ERAKAEDFDA
     EESELIKEEN EQEEEVFDQV GEILGTLIKT FKAAFLPFFD ELSSYLTPMW GKDKTAEERR
     IAICIFDDVA EQCREAALKY YETYLPFLLE ACNDENQDVR QAAVYGLGVC AEFGGSVVKP
     LVGEALSRLN VVIRHPNALQ PENLMAYDNA VSALGKICQF HRDSIDAAQV VPAWLNCLPI
     KGDLIEAKIV HEQLCSMVER SDSDLLGPNH QYLPKIVSVF AEILCGKDLA TEQTLSRIVN
     LLKQLQQTLP PATLASTWSS LQPQQQLALQ SILS
//