ID A0A067FD08_CITSI Unreviewed; 561 AA.
AC A0A067FD08;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Serine/threonine-protein phosphatase {ECO:0000256|RuleBase:RU004273};
DE EC=3.1.3.16 {ECO:0000256|RuleBase:RU004273};
GN ORFNames=CISIN_1g007145mg {ECO:0000313|EMBL:KDO65188.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO65188.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO65188.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] +
CC phosphate; Xref=Rhea:RHEA:47004, Rhea:RHEA-COMP:11060, Rhea:RHEA-
CC COMP:11605, ChEBI:CHEBI:15377, ChEBI:CHEBI:30013, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:61977; EC=3.1.3.16;
CC Evidence={ECO:0000256|RuleBase:RU004273};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SIMILARITY: Belongs to the PPP phosphatase family.
CC {ECO:0000256|RuleBase:RU004273}.
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DR EMBL; KK784904; KDO65188.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067FD08; -.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0017018; F:myosin phosphatase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.60.21.10; -; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR006186; Ser/Thr-sp_prot-phosphatase.
DR PANTHER; PTHR45668; SERINE/THREONINE-PROTEIN PHOSPHATASE 5-RELATED; 1.
DR PANTHER; PTHR45668:SF9; SERINE_THREONINE-PROTEIN PHOSPHATASE 7; 1.
DR Pfam; PF00149; Metallophos; 1.
DR PRINTS; PR00114; STPHPHTASE.
DR SMART; SM00156; PP2Ac; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR PROSITE; PS00125; SER_THR_PHOSPHATASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|RuleBase:RU004273};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120}.
FT DOMAIN 287..292
FT /note="Serine/threonine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS00125"
FT REGION 525..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 63350 MW; D8868C898F956648 CRC64;
MDLLPLIGDV DEFKEIMGII NKEMDLVSLS DENLRRVFMI FEIAGGVVNG RTKQVTEADA
EQLWCSSVDG VVAVAKQVID YACEMNFQDL DGPLKQAVVE ILRSACNIVS KQRVFDSSLQ
GLLEELQVEV GSTMRERLVG GKLENLTKEQ DTLPLSWPRN GRISLEWIQL LISTFKWSSW
KDPKEFRNVM PVTVVKKLIS AASKIMREER NCVKLRVRED SEVIVVGDIL GQFHDLVALF
EENAGFPSDH RYFVFNGNYV DKGSWGLEVL LVLLAWKVLM PHRVYLLRGN HETKNCTLAY
GFWAELCTKF GKKDCKLVFD KCLECFRTLP LATIIAQGVY TTHGGLFRRT CSASTQCSTG
EKRQKLDTLS LGSLREFAKV NRFLEDVPEN DLLSDVLWSD PSSEAGLREN TKKFGLLWGP
DCTEEFLKEN HLKLIIRSHE GPDARTGADD ARNMLNGYSK DHDTVSGELY TLFTAPNYPQ
VDGFDNVGAY AVLKPPLFDS PLFLQLKAAE KPEVPPYDVF IYEDMDSDEG EDSRLTDSDE
EQDMVSRDAV GKKDSTLMVS W
//
