ID A0A067FVT6_CITSI Unreviewed; 914 AA.
AC A0A067FVT6;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Glutamate receptor {ECO:0000256|PIRNR:PIRNR037090};
GN ORFNames=CISIN_1g002505mg {ECO:0000313|EMBL:KDO71514.1};
OS Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO71514.1, ECO:0000313|Proteomes:UP000027120};
RN [1] {ECO:0000313|EMBL:KDO71514.1, ECO:0000313|Proteomes:UP000027120}
RP NUCLEOTIDE SEQUENCE.
RG International Citrus Genome Consortium;
RA Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Glutamate-gated receptor that probably acts as non-selective
CC cation channel. {ECO:0000256|PIRNR:PIRNR037090}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glutamate-gated ion channel (TC 1.A.10.1)
CC family. {ECO:0000256|ARBA:ARBA00008685, ECO:0000256|PIRNR:PIRNR037090}.
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DR EMBL; KK784889; KDO71514.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067FVT6; -.
DR STRING; 2711.A0A067FVT6; -.
DR PaxDb; 2711-XP_006467097-1; -.
DR eggNOG; KOG1052; Eukaryota.
DR Proteomes; UP000027120; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IBA:GO_Central.
DR GO; GO:0038023; F:signaling receptor activity; IBA:GO_Central.
DR CDD; cd13686; GluR_Plant; 1.
DR CDD; cd19990; PBP1_GABAb_receptor_plant; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR001828; ANF_lig-bd_rcpt.
DR InterPro; IPR044440; GABAb_receptor_plant_PBP1.
DR InterPro; IPR019594; Glu/Gly-bd.
DR InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR InterPro; IPR001320; Iontro_rcpt_C.
DR InterPro; IPR017103; Iontropic_Glu_rcpt_pln.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR001638; Solute-binding_3/MltF_N.
DR PANTHER; PTHR18966:SF453; GLUTAMATE RECEPTOR; 1.
DR PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR Pfam; PF01094; ANF_receptor; 1.
DR Pfam; PF00060; Lig_chan; 1.
DR Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR Pfam; PF00497; SBP_bac_3; 1.
DR PIRSF; PIRSF037090; Iontro_Glu-like_rcpt_pln; 1.
DR PRINTS; PR01176; GABABRECEPTR.
DR SMART; SM00079; PBPe; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR037090-50};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303, ECO:0000256|PIRNR:PIRNR037090};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286,
KW ECO:0000256|PIRNR:PIRNR037090};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR037090};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|PIRNR:PIRNR037090};
KW Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR037090}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..914
FT /note="Glutamate receptor"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001637456"
FT TRANSMEM 594..612
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 834..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 473..814
FT /note="Ionotropic glutamate receptor C-terminal"
FT /evidence="ECO:0000259|SMART:SM00079"
FT DISULFID 763..817
FT /evidence="ECO:0000256|PIRSR:PIRSR037090-50"
SQ SEQUENCE 914 AA; 102012 MW; E08BFAE4CCFE48C9 CRC64;
MTKIYLLALV VVYNFCFSAG ISMNGVSTIP PVLNIGAVFA LNSTIGKVAK VAIEAAVEDV
NSNPAILGGT KLKLTVHDTN YSRFLGMVEA LTLLENETVA IIGPQFSVIA HLVSHIANEF
QVPLLSFAAT DPSLSSLQYP FFVRTTQSDL YQMAAIADIV DYFGWRNVIA LYVDDDHGRN
GIAALGDKLA EKRCRLSHKV PLSPKGSRNQ IIDTLLTVSS MMSRILILHT YDIWGLEVLN
AAKHLRMMES GYVWIVTDWL SSILDTDSQL HSEKMDDIQG VLTLRMYTQS SEEKRKFVTR
WRHLTRRNTL NGPIGLNSFG LYAYDTLWLL AHAIGAFFDQ GGNISFSEDS KLSELSRGDM
RFSSVSIFNG GKMLLDNILQ VNMTGVTGPI KFTSDRDLIN PAYEVINVIG TGSRRIGYWS
NHSGLSVVPP EALYKEPSNR SASSQHLYSA VWPGQTTQKP RGWVFPNNGR HLRIGVPSQV
IYPEFVAQGK GTDKFSGYCI DVFTAVLELL PYAVPYKLVP FGDGHNSPKR FDLLRLVSEE
VYDAAVGDFA ITTERTKMVD FTQPYIESGL VVVAPIKKLN SNAWAFLNPF TPKMWCVTGI
FFLVVGVVVW ILEHRLNDDF RGPPRRQIGT ILWFSFSTLF FSHKERTVNS LSRLVLIIWL
FVVLILTSSY TASLTSILTV EQLSSPIKDI QSLVASSDPI GYQRGSFAEN YLTDELNIDK
SRLVPLNTAE EYEKALTDGP KNGGVSAVID ERAYMEVFLS TRCEFSIIGQ EFTRIGWGFA
FPRDSPLAVD MSIAILELSE NGDLQRIHDK WLTRSACSSQ GAKQEADQLH LKSFWGLFVL
CGVACLLALL IYLIQIVRQF ARHYLDLQEL ESAGPSSQSS RLQTFISFAG EKEVVIKKSL
QEKKIGEGVN WRHR
//
