ID   A0A067H664_CITSI        Unreviewed;       738 AA.
AC   A0A067H664;
DT   03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT   03-SEP-2014, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN   ORFNames=CISIN_1g004666mg {ECO:0000313|EMBL:KDO87344.1};
OS   Citrus sinensis (Sweet orange) (Citrus aurantium var. sinensis).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Sapindales; Rutaceae; Aurantioideae; Citrus.
OX   NCBI_TaxID=2711 {ECO:0000313|EMBL:KDO87344.1, ECO:0000313|Proteomes:UP000027120};
RN   [1] {ECO:0000313|EMBL:KDO87344.1, ECO:0000313|Proteomes:UP000027120}
RP   NUCLEOTIDE SEQUENCE.
RG   International Citrus Genome Consortium;
RA   Gmitter F., Chen C., Farmerie W., Harkins T., Desany B., Mohiuddin M.,
RA   Kodira C., Borodovsky M., Lomsadze A., Burns P., Jenkins J., Prochnik S.,
RA   Shu S., Chapman J., Pitluck S., Schmutz J., Rokhsar D.;
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; KK784873; KDO87344.1; -; Genomic_DNA.
DR   RefSeq; XP_006479898.1; XM_006479835.2.
DR   AlphaFoldDB; A0A067H664; -.
DR   STRING; 2711.A0A067H664; -.
DR   PaxDb; 2711-XP_006479898-1; -.
DR   GeneID; 102612067; -.
DR   KEGG; cit:102612067; -.
DR   eggNOG; KOG2166; Eukaryota.
DR   OrthoDB; 21270at2759; -.
DR   Proteomes; UP000027120; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR   GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF138; CULLIN-1-RELATED; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000027120};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          383..613
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   738 AA;  86105 MW;  2E0B92B5BD047856 CRC64;
     MDRKTIDLDQ GWDYMQKGIT KLKRILEGLP ESPFSSEEYM MLYTTIYNMC TQKPPHDYSQ
     QLYDKYKQAF EEYISSMVLP SLSEKHDEYM LRELVKRWAN HKVMVRWLSR FFHYLDRYFI
     ARRSLPALNE VGLTCFREQV YDALKNKAKD AIIALIDKER EGEQIDRALL KNVLDIFVEI
     GMGQMDSYEK DFEEHMLQDT GAYYSRKASN WILEDSCPEY MIKAEECLKK ERDRVSHYLH
     SSSEPKLVEK VQHELLVVYA TELLEKEQSG CRALLREDKV EDLSRMYRLY HKIPKGLEPV
     ANVFKQHITA EGTVLVQQAE DAATNQGGSS GAVQEQVLIR KIIELHDKYM EYVTNCFINH
     TLFHKALKEA FEIFCNKAVG GSSSSELLAT FCDNILKKGG NEKLSDEAIE ETLEKVVKLL
     AYISDKDLFA EFYRKKLARR LLFDRSANDD HERSILTKLK QQCGGQFTSK MEGMVTDLTL
     ARENQTSFEE YLSNNQNAHP GIDLSVTVLT TGFWPSYKSS DLNLPSEMVK CVEVFKGFYE
     TKTKHRKLTW IYSLGQCNIN GKFEQKNIEL IVSTYQAATL LLFNTSDRLS YSEIMTQLNL
     THDDLVRLLH SLSCAKYKIL LKEPNTKTIS QSDHFEFNSK FTDRMRRIKI PLPPVDERKK
     IVEDVDKDRR YAIDAALVRI MKSRKVLGHQ QLVSECVEQL SRMFKPDIKA IKKRMEDLIT
     RDYLERDKEN PNMFRYLA
//