ID A0A067N9V4_PLEOS Unreviewed; 778 AA.
AC A0A067N9V4;
DT 03-SEP-2014, integrated into UniProtKB/TrEMBL.
DT 03-SEP-2014, sequence version 1.
DT 28-JUN-2023, entry version 23.
DE RecName: Full=Nitrogen permease regulator 3 {ECO:0000256|RuleBase:RU368069};
DE AltName: Full=Required for meiotic nuclear division protein 11 {ECO:0000256|RuleBase:RU368069};
GN ORFNames=PLEOSDRAFT_176930 {ECO:0000313|EMBL:KDQ24634.1};
OS Pleurotus ostreatus PC15.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Pleurotineae; Pleurotaceae; Pleurotus.
OX NCBI_TaxID=1137138 {ECO:0000313|EMBL:KDQ24634.1, ECO:0000313|Proteomes:UP000027073};
RN [1] {ECO:0000313|Proteomes:UP000027073}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PC15 {ECO:0000313|Proteomes:UP000027073};
RX PubMed=24958869; DOI=10.1073/pnas.1400592111;
RA Riley R., Salamov A.A., Brown D.W., Nagy L.G., Floudas D., Held B.W.,
RA Levasseur A., Lombard V., Morin E., Otillar R., Lindquist E.A., Sun H.,
RA LaButti K.M., Schmutz J., Jabbour D., Luo H., Baker S.E., Pisabarro A.G.,
RA Walton J.D., Blanchette R.A., Henrissat B., Martin F., Cullen D.,
RA Hibbett D.S., Grigoriev I.V.;
RT "Extensive sampling of basidiomycete genomes demonstrates inadequacy of the
RT white-rot/brown-rot paradigm for wood decay fungi.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:9923-9928(2014).
CC -!- FUNCTION: Mediates inactivation of the TORC1 complex in response to
CC amino acid starvation. Required for meiotic nuclear division.
CC {ECO:0000256|RuleBase:RU368069}.
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000256|RuleBase:RU368069};
CC Peripheral membrane protein {ECO:0000256|RuleBase:RU368069}.
CC -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000256|ARBA:ARBA00010546,
CC ECO:0000256|RuleBase:RU368069}.
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DR EMBL; KL198011; KDQ24634.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A067N9V4; -.
DR STRING; 1137138.A0A067N9V4; -.
DR HOGENOM; CLU_021922_0_0_1; -.
DR InParanoid; A0A067N9V4; -.
DR OrthoDB; 1381214at2759; -.
DR Proteomes; UP000027073; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-UniRule.
DR GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR InterPro; IPR005365; Npr3.
DR PANTHER; PTHR13153; CGTHBA PROTEIN -14 GENE PROTEIN; 1.
DR PANTHER; PTHR13153:SF5; GATOR COMPLEX PROTEIN NPRL3; 1.
DR Pfam; PF03666; NPR3; 1.
PE 3: Inferred from homology;
KW Meiosis {ECO:0000256|RuleBase:RU368069};
KW Reference proteome {ECO:0000313|Proteomes:UP000027073};
KW Signal {ECO:0000256|RuleBase:RU368069, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..778
FT /note="Nitrogen permease regulator 3"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001641944"
FT REGION 25..75
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 91..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 182..204
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 639..683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..106
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 639..666
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 778 AA; 87925 MW; F34B5975E599CAE1 CRC64;
MAETLLGLLL VTSSAKGSSL VFRWPPSPSS TPRYKRARPG CSSYPKHLDN PYRASHYSDA
PGGPPEEIIV DDNESDYQWK RPSAMRDRSM SFTHAASHSA SGGASPSEED SFHLEEAAAK
DDYDRLLGYS SEFLAGLLCP QRSLCHQKFE LFVDDLAFIG HPVCAEKDGG WRFRLEKGRM
HSRGRESRND RSPASSADSE SPGTQSAWLH TFHLVLVLDL PDPSSSAAGN VDKYFDIIYE
QIAFTTAAVL FQEQVMSNFV EAECDHLGSI KDACVAKDTF QGEPLSAYVA KALEASSIAP
AMKTIYEAIK SSTIAYITIH YLPLELQLPP YLDSLLHSEE DDEMEYWAPS DGEDSPSWGV
ELKYGWRLPI LAPWKSILLL DGPADADPYA NLRGPHLSAG DRTLAEGLLK FLELASVILS
LADLAALLDW DLEAQVYPTV RWLVLHRRAK VIDTVHAGLK TIFTLPPKFD EPLSTLSAEF
SKDFASTSVP PLPQILAIIS SSASKQSENH FFATVVRDKA QIPLYHNVVL WMLKRDLLHT
LHLRIRVVAT RELKARVKAD WARHLESKRL RKGRRSRNQS FVQDVDNQYP SSELQQGISW
LSLSPKSARR YSRRKASNES RQSKLSELII PEAFEEDLDI HDRDDDVDPE LDEEDEEDDE
DEVAADENGS EQQHPWSSMI NDPGTATPLE RRWLAAMSEG KDPRIARRFE HCTLKHNFDR
SSRSLIDFTG YRIAMLYMAY VSYKREGYYF RGIEDKERIC GETKYRDNNM LQWRILDS
//
