ID A0A068QTK0_9GAMM Unreviewed; 2242 AA.
AC A0A068QTK0;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 48.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:CDG17981.1};
GN ORFNames=XDD1_2282 {ECO:0000313|EMBL:CDG17981.1};
OS Xenorhabdus doucetiae.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Morganellaceae; Xenorhabdus.
OX NCBI_TaxID=351671 {ECO:0000313|EMBL:CDG17981.1, ECO:0000313|Proteomes:UP000032721};
RN [1] {ECO:0000313|EMBL:CDG17981.1, ECO:0000313|Proteomes:UP000032721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FRM16 / DSM 17909 {ECO:0000313|Proteomes:UP000032721};
RA Genoscope - CEA;
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
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DR EMBL; FO704550; CDG17981.1; -; Genomic_DNA.
DR RefSeq; WP_045970991.1; NZ_VNHN01000038.1.
DR STRING; 351671.XDD1_2282; -.
DR KEGG; xdo:XDD1_2282; -.
DR HOGENOM; CLU_000022_0_3_6; -.
DR OrthoDB; 9757559at2; -.
DR Proteomes; UP000032721; Chromosome.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd12117; A_NRPS_Srf_like; 2.
DR CDD; cd19544; E-C_NRPS; 1.
DR CDD; cd19531; LCL_NRPS-like; 1.
DR Gene3D; 3.30.300.30; -; 2.
DR Gene3D; 3.40.50.980; -; 4.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 2.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 2.
DR Pfam; PF13193; AMP-binding_C; 2.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 2.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 2.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 1042..1116
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2133..2208
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 2242 AA; 247630 MW; F442D552E32100FF CRC64;
MARTHMNLDD LKRAVLEKRI EEQLQVRGCQ QQPSLITPAD RHRPLPLSFA QQRLWFLSQI
DPAAALAYHL PVILQLTGQL DLHALATSLD RLIARHESLR TRFVLVEGQP CQQLDPADIG
FALSYHDLRQ TDPDLHPRQV AELADLEALT PFDFAQGPLI RGQLLQLADE EHVLLLTLHH
IITDGWSTGV LVRELGAFYR AALDGRDASL PPLPIQYADY AVWQHEQLKE TALTEQRDFW
RAQLEGAPAL LELPTDRPRP AVQTYAGDHV AFQLDAPLLA SLKALGQRHH STLFMIMLTA
WSSVLARLTG QEEIVIGTPV ANRSQHELEG LMGFFVNTLA LRVTFNDHLS VKELLVQVRE
RALAAYAHQD LPFEQVVEAL QPERSLSYSP IFQVMLALNN TPTQALTLPN LQLTAMEPAR
RGAHFDLALS LSELSLSELS LSETETGLVG DLEYATDLFD RATVERMVAY FTHTLTAMAA
DETQPVATLP MLPASERQQL LIDFNATQAD FPQDALIHQL IETQAEQRPD ATALVFEDKT
LSYGELNRRA NQLAHYLIAL GVHPDDRVAI CAERSPELIV GLLAILKASG AYLPLDPAYP
AERLAYMLED ATPAVLLTQT AQRDKLPGSL PTVLLDHVLD EQDPLLAAQL AAQPADNPDV
QALGLTARHL AYVIYTSGST GQPKGVMVEH RNVLRLIVNS GFADISPDDC IAHCANISFD
AATWEVWSGL VHGARLLLIP EKALLQPAEF GHCLSAQGVS ILFLTSALFN HYAHLIGPSL
AGLRYVLFGG EQTDTRPATH LRTEYPPQYL LHMYGPAETT TFATAYIIPE AEENKDSHQT
IPIGRPIANT QIYILDPQGQ PVPLGVTGEI HIGGAGVARG YLNRPELTAE RFLADPFSAE
PDARMYKTGD LGRWLPDGNI EYLGRNDFQV KLRGFRIELG EIEAQLRQCH GVREAVVIAR
EAAFDENTGD QKRLVAYLRP QDGVELVPAE LRQQLARHLA DYMLPSAFVT LAAFPLTPNG
KLDRQALPAP DSSAMVVRSY ESPASETEIA LAQIWQNLLG LEQVSRYDHF FELGGHSLMI
VSLIEALRST GWKLDVRSVF AAPVLADMAQ TLQRDNSTFV VPPNLIPEDC TSITPAMLPL
VSLSQTEIDA IIATLPGGAS NIQDIYPLAP LQAGILFHYL MQAQGDTYLL QSLLDFDTRE
RLDRFLDALQ RVINRHDILR TSVYWQGLEQ PVQVVWRQAP LNIHVFTPTT TDNVPAQLQA
HTDPHRHRLD LTRAPLFAAD IAHDPVQNEW LLALRFHHLV SDHMTLELIF AEIALMLQGQ
ETLPTALPYR NFIAQTLNVP AAEHEDYFRT RLADIDEPTA PFGVLSIPDN KSSNNEIPSD
DNAIAEARLS VDPELAQAIR AQARHLKVSP SVLFHVAWAQ VLAKTCGRDD VVFGSVLLGR
LQGGAGADQI LGMFINTLPV RISLADHSVQ AVVQATYHDL MTLLEHEQAP LALAQGYSGV
ALSMPLFSAL LNYRHSQANE ENANTVWSGM RVIATQERTN YPITLSVDDL GEGFNLTAHT
VANIDPVRLI HYLLTAIRGL VDALTHNPQQ RILDLPILPT AERQQLLVDF NITQTATQTD
FPQEALIHAL FEAQAAQRPD ATALVFEDQR ISYGELNRRA NQLAHYLLAL GVRPDDCIAV
CLERSFETVV CLLGILKAGG AYLPLDPAYP TERLADMLED AAPVVLLTQT AQIDKLPATV
PVVTLDTLNT SLEKQPIHNP DTQALGLTSH HLAYVIYTSG STGQPKGVMV EHRNVLRLII
NSGFTEISPN DCVAHCANMA FDASTWEIWS ALLNGGCLHI VPQSVLLDPP RFCASLIRGN
VTALWLTAGL FNQYLDALKP LFGQLRYLLI GGDVLDPRKI QQVQQADSPP IHLINGYGPT
ETTTFAATYA IASPVNVAHS IPIGRPIAST QIYILDRQGQ PVPLGVAGEI HIGGAGVARG
YLNRPELTKA RFLRDPFSPE PAARMYKTGD LGRWLPDGNI EYLGRNDFQV KLRGFRIEPG
EIEAQLRQCH GVQEAVVIAR EDQRLVAYLR AQAGVELLPA ELRRQLAQHL ADYMLPSAFV
TLATFPLTPN GKLDRQALPA PDASALVIRH YEAPNSEEEM MLAQIWQDLL GVEQVGRHDH
FFELGGHSLM LVQLATRIQD EFWVDIPISS LFLSPQLAEQ AAIILAAQLE SIGKNEFESL
QNTLDSMSTE ELIAMLGGDS HQ
//
