ID A0A068RSN6_9FUNG Unreviewed; 907 AA.
AC A0A068RSN6;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Subtilisin-like serine protease pr1c {ECO:0000313|EMBL:CDH52730.1};
GN ORFNames=LCOR_04174.1 {ECO:0000313|EMBL:CDH52730.1};
OS Lichtheimia corymbifera JMRC:FSU:9682.
OC Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC Mucoromycetes; Mucorales; Lichtheimiaceae; Lichtheimia.
OX NCBI_TaxID=1263082 {ECO:0000313|EMBL:CDH52730.1, ECO:0000313|Proteomes:UP000027586};
RN [1] {ECO:0000313|EMBL:CDH52730.1, ECO:0000313|Proteomes:UP000027586}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JMRC:FSU:9682 {ECO:0000313|Proteomes:UP000027586};
RA Schwartze V.U., Winter S., Shelest E., Marcet-Houben M., Horn F.,
RA Wehner S., Hoffmann K., Riege K., Sammeth M., Nowrousian M., Valiante V.,
RA Linde J., Jacobsen I.D., Marz M., Brakhage A.A., Gabaldon T., Bocker S.,
RA Voigt K.;
RT "Gene expansion shapes genome architecture in the human pathogen
RT Lichtheimia corymbifera: an evolutionary genomics analysis in the ancient
RT terrestrial Mucorales (Mucoromycotina).";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240,
CC ECO:0000256|RuleBase:RU003355}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CDH52730.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CBTN010000014; CDH52730.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068RSN6; -.
DR STRING; 1263082.A0A068RSN6; -.
DR VEuPathDB; FungiDB:LCOR_04174.1; -.
DR OrthoDB; 662485at2759; -.
DR Proteomes; UP000027586; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd07489; Peptidases_S8_5; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR Gene3D; 2.60.40.1710; Subtilisin-like superfamily; 1.
DR InterPro; IPR010435; Fn3_5.
DR InterPro; IPR046450; PA_dom_sf.
DR InterPro; IPR003137; PA_domain.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034187; Peptidases_S8_5.
DR PANTHER; PTHR43806:SF59; CEREVISIN-RELATED; 1.
DR PANTHER; PTHR43806; PEPTIDASE S8; 1.
DR Pfam; PF06280; fn3_5; 1.
DR Pfam; PF02225; PA; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52025; PA domain; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00136; SUBTILASE_ASP; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000027586};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..907
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001652665"
FT DOMAIN 187..580
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 415..489
FT /note="PA"
FT /evidence="ECO:0000259|Pfam:PF02225"
FT DOMAIN 638..758
FT /note="Fn3-like"
FT /evidence="ECO:0000259|Pfam:PF06280"
FT REGION 230..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 196
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 255
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 561
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 907 AA; 97146 MW; 6E3F4C1A2775F70F CRC64;
MKFFSPLWGL AAAATLLLES NPVFAANVHP SQISKKEFEV VPGRYIVEFS GGNVDASSKK
LTELLNGKFD DTKVSIVRSW NHSFMRGISL QIDTVKNSKT KSKSNDDDED LVVESMSTSN
DNVLDSVMKA LQDEALVANV YPVRIIPRPQ LTATPLSSGA KGIDTGLLEP HSMTQVDRVH
KELKNKGKGI KVGVIDSGVD YKHEALGGCL GKGCKVAYGY DLVGDDYNAE IPGSTPKPDD
DPLDDCGKDS GASGHGTHVS GIIAGKSENF TGVAPEATLG MWRVFGCKGS ASNDVIIQAM
LDAYEAGVDI ISMSLGDSLG WSETADSVVA QRIVESGVPV IIAAGNEGAS GAFTAGTPSV
GHGPVSVASF DNNYFIAKQF SADGLDGKQI YSPSESSGQI PDGDLALGDK NVDSSSDACK
AENVPKEVKG KIGLVRRGSC TFDEKAANLA KAGAIGALVF NAEGDVFTPS TTTAKIPVAG
VSNEIGLKLV DLIKGGKTVK ATFDHQESTL PVSTGKTVSS FSSVGPSYEN DLKPEIAGIG
GNVYSTLPRY LGGWGMMSGT SMATPYVSGA VALYLKQAQK DHDLSTKPKF ITEQFQHYAY
KAPNVNVVGV DSPLAQGAGL IQVYDTLTQN VHITPGAISF NDTANIVRTQ KLTIKNNGHS
TVSYQISNNV SVAIQPYDQN PYIFSEPATY INDERNAAAS IKFNKKTIKL GPGKSATIKF
TVTPPTKHNS PDDHIMYGGF IQFKSQNSKH KDLTVPYFGI VGDQRKLPLF MPDSPVVTDE
NQSKLYDSKD DVFVFDPKNA TTVPYFIYGF QTPTAHLKAT LYTEKGKALG TVWSADYEIG
RNTLSEPYTA TIWDGTYKPT IGKFEFPISL QAPKGKYRIG WKALKLLGNP NKSQDWESWT
SCIIQVV
//
