ID   A0A068YDM0_ECHMU        Unreviewed;       749 AA.
AC   A0A068YDM0;
DT   01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Ankyrin domain repeat containing protein {ECO:0000313|EMBL:CDS41395.1};
GN   ORFNames=EmuJ_000904300 {ECO:0000313|EMBL:CDS41395.1};
OS   Echinococcus multilocularis (Fox tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Cyclophyllidea; Taeniidae; Echinococcus.
OX   NCBI_TaxID=6211 {ECO:0000313|EMBL:CDS41395.1};
RN   [1] {ECO:0000313|EMBL:CDS41395.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23485966; DOI=10.1038/nature12031;
RA   Tsai I.J., Zarowiecki M., Holroyd N., Garciarrubio A., Sanchez-Flores A.,
RA   Brooks K.L., Tracey A., Bobes R.J., Fragoso G., Sciutto E., Aslett M.,
RA   Beasley H., Bennett H.M., Cai J., Camicia F., Clark R., Cucher M.,
RA   De Silva N., Day T.A., Deplazes P., Estrada K., Fernandez C., Holland P.W.,
RA   Hou J., Hu S., Huckvale T., Hung S.S., Kamenetzky L., Keane J.A., Kiss F.,
RA   Koziol U., Lambert O., Liu K., Luo X., Luo Y., Macchiaroli N., Nichol S.,
RA   Paps J., Parkinson J., Pouchkina-Stantcheva N., Riddiford N., Rosenzvit M.,
RA   Salinas G., Wasmuth J.D., Zamanian M., Zheng Y., Cai X., Soberon X.,
RA   Olson P.D., Laclette J.P., Brehm K., Berriman M., Garciarrubio A.,
RA   Bobes R.J., Fragoso G., Sanchez-Flores A., Estrada K., Cevallos M.A.,
RA   Morett E., Gonzalez V., Portillo T., Ochoa-Leyva A., Jose M.V., Sciutto E.,
RA   Landa A., Jimenez L., Valdes V., Carrero J.C., Larralde C.,
RA   Morales-Montor J., Limon-Lason J., Soberon X., Laclette J.P.;
RT   "The genomes of four tapeworm species reveal adaptations to parasitism.";
RL   Nature 496:57-63(2013).
RN   [2] {ECO:0000313|EMBL:CDS41395.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Zhang Y., Guo Z.;
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the ANKLE2 family.
CC       {ECO:0000256|ARBA:ARBA00007597}.
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DR   EMBL; LN902841; CDS41395.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A068YDM0; -.
DR   STRING; 6211.A0A068YDM0; -.
DR   eggNOG; ENOG502QQ4Z; Eukaryota.
DR   OMA; WARIYPN; -.
DR   GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR12349; ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2; 1.
DR   PANTHER; PTHR12349:SF4; ANKYRIN REPEAT AND LEM DOMAIN-CONTAINING PROTEIN 2; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   SMART; SM00248; ANK; 2.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
PE   3: Inferred from homology;
KW   ANK repeat {ECO:0000256|ARBA:ARBA00023043};
KW   Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW   Cell division {ECO:0000256|ARBA:ARBA00022618}.
FT   REGION          558..580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        559..580
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   749 AA;  82846 MW;  B649AF0F8ADEC999 CRC64;
     MSDSPDDSDE EFFDCTEPFP SKFYAVAVPR SSPGAGLFAN ITQAKSRLRS VKGSRLKAFD
     SIQDASDYSA CPVAEGSEHP LPIPEGEIVK FPSIRQADLL RLRKYIEAND IDLIEKCISA
     NPMYLLTGYD TPTILQLVFR FNAIHIAAKL GHADVIKLII SYLESSEFWA RIYPNADVHT
     AKERRLRVLD LYLNSPETGS LSTPLHLASK FGHVECVRVL ASHPATLLDL RDASGDTALD
     TACTRLLVNE SLSLEQKSLR RQIIARALDE RYVVLVDRSE LVGGAEEIKP TILPLGLMGR
     QLHHLLSATG QLSCPGVSEF CTHLTAHRLA AAAATPSTPP ASPTPMSPPL PFSPRSMVSP
     SRQSPVAAVH SPSVAGIDGT ARGGSADLRA FGVTGHLVRV RAILGPLDTE EAQRAVASWR
     RPQNPFWTNL RLMDAEKGYE RYGRRLATEL DTKWTEHWAF LDDFADLRSD YGLGLLNDYL
     AQFYVSTKKT QQSPAVIHGS FPCHILNFDE SMEESSPKRT PNKRVKCEKN GAPVVWSNAR
     ERLCPWTAYR EDNNPEQVLS DGLEESSSSS TSSGNSYSTE CDVDPKFLSP KQISPVIGML
     NNFIVSSPLR FILPPFCTSG SSPTMSRPEK RISMFSHSED VTSTPLRHAP LTLSRKTTSA
     KQKSARRHVT DGMWPSLLEG RTSDRGSRTT HLHASITPAE VSVRNALNCD VTPDENSNQN
     WTRETGVNLE NYPFVKQWKR ELDLSIQHS
//