ID A0A068YNK3_9BURK Unreviewed; 563 AA.
AC A0A068YNK3;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Long-chain-fatty-acid--CoA ligase {ECO:0000256|ARBA:ARBA00039545};
DE EC=6.2.1.3 {ECO:0000256|ARBA:ARBA00026121};
DE AltName: Full=Long-chain acyl-CoA synthetase {ECO:0000256|ARBA:ARBA00042773};
OS Polaromonas sp. CG9_12.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1504672 {ECO:0000313|EMBL:CDS53232.1, ECO:0000313|Proteomes:UP000043372};
RN [1] {ECO:0000313|EMBL:CDS53232.1, ECO:0000313|Proteomes:UP000043372}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Smith H.J., Foreman C.M., Ramaraj T.;
RT "Draft Genome Sequence of a Metabolically Diverse Antarctic Supraglacial
RT Stream Organism, Polaromonas sp. Strain CG9_12, Determined Using Pacific
RT Biosciences Single-Molecule Real-Time Sequencing Technology.";
RL Genome Announc. 2:1-2(2014).
CC -!- PATHWAY: Lipid metabolism; fatty acid beta-oxidation.
CC {ECO:0000256|ARBA:ARBA00005005}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
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DR EMBL; CCJP01000005; CDS53232.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A068YNK3; -.
DR STRING; 1504672.gene:199032466; -.
DR eggNOG; COG0318; Bacteria.
DR Proteomes; UP000043372; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:UniProtKB-EC.
DR CDD; cd05936; FC-FACS_FadD_like; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43767; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR PANTHER; PTHR43767:SF8; LONG-CHAIN-FATTY-ACID--COA LIGASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:CDS53232.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000043372}.
FT DOMAIN 36..428
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 479..553
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 563 AA; 61355 MW; C235205F12DEDC5D CRC64;
MMKPNEVERP WLKAYPAGVP ADVDASQYPS LVVLMEESFK THKDRVAYSF MGKEITFGQT
NNLSLAFGAY LQGLGLLRGD RVAIMMPNVP QYPVAVAAIL RAGYVVVNVN PLYTPRELEH
QLKDSGAKAI VIVENFASTL EQCLANTPVK HVVLCSMGDQ LGLLKGTLVN YVVRSVKKMV
PPFNLPGAVR FNDALAQGTR GVLKRPDIKP DDIAVLQYTG GTTGVSKGAV LLHRNVIANV
LQSEAWNGPA MASLGAGEQP VYVCALPLYH IFAFTVNMML GMRTGGKNIL IPNPRDLPAV
LKELAKHKVN SFPAVNTLFN GLANHPDFNT VDWSHLKISL GGGMAVQSAV AKLWLQKTGC
PICEGYGLSE TSPSASCNPT NSKTFTGTIG VPIPGTWFKL LDDDGHEVAP GQPGEIAIKG
PQVMAGYWQR PDETDKVMTP DGYFKSGDIG IIDENGFFKI IDRKKDMVLV SGFNVYPNEI
EEIVSTMNGV MECACVGVID EKSGEAVKLV IVKKNPDLTE ADVRAFCKEN LTGYKQPRVV
EFRTELPKTP VGKILRRELR DKR
//
