ID A0A072PI69_9EURO Unreviewed; 617 AA.
AC A0A072PI69;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RNA binding protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=A1O9_08869 {ECO:0000313|EMBL:KEF55215.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF55215.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF55215.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF55215.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF55215.1}.
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DR EMBL; AMGV01000008; KEF55215.1; -; Genomic_DNA.
DR RefSeq; XP_013257805.1; XM_013402351.1.
DR AlphaFoldDB; A0A072PI69; -.
DR STRING; 1182545.A0A072PI69; -.
DR GeneID; 25283779; -.
DR VEuPathDB; FungiDB:A1O9_08869; -.
DR HOGENOM; CLU_022834_2_0_1; -.
DR OrthoDB; 228305at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000175; F:3'-5'-RNA exonuclease activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd06133; ERI-1_3'hExo_like; 1.
DR CDD; cd12452; RRM_ARP_like; 1.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR InterPro; IPR047201; ERI-1_3'hExo-like.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR034351; Nrp1_RRM.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR000504; RRM_dom.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR23111:SF40; RNA-BINDING PROTEIN INVOLVED IN HETEROCHROMATIN ASSEMBLY-RELATED; 1.
DR PANTHER; PTHR23111; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00929; RNase_T; 1.
DR Pfam; PF00076; RRM_1; 1.
DR Pfam; PF00641; zf-RanBP; 2.
DR SMART; SM00360; RRM; 1.
DR SMART; SM00547; ZnF_RBZ; 2.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF54928; RNA-binding domain, RBD; 1.
DR PROSITE; PS50102; RRM; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 2.
DR PROSITE; PS50199; ZF_RANBP2_2; 2.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00176};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 253..331
FT /note="RRM"
FT /evidence="ECO:0000259|PROSITE:PS50102"
FT DOMAIN 352..381
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 428..459
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT REGION 558..617
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 558..576
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 617 AA; 66249 MW; 3D7A94EE19011AD3 CRC64;
MATAAPPVPK LDRYVIIHVA TTCDEHGVYV TKDSAEVIEL GWILLDAKTC DEIYRESVLV
KPINTPITPL CTSLTTLTWE HVRNAGSFRD AVARFDHFAQ EHLISKNLEF SFVTLDAWDL
RVQLPREARD KSVVLPAYLQ HSRTFDLRSE YARWQQHHPE SLPFGPSSLA NICAALEVEP
VQSSAPIKHN LPFHLQALAP ASPRRAMEEA VTLARVLRGL IRKSQPAHDH PEILTRPMDA
RADVNAFLKE RSKVLHMNGL PHDTTQSELE SWFTQFGGRP IAFWTLRTPD QHKPTGSGFA
VFSSHEEAAE SLCMNGRALN EKAIEVSPSS SRVLDRAAEI LTPFPPSKNR PRPGDWNCPS
CGFSNFQRRT ACFRCSFPAA GSGAGDPYNA NAFPYHHGYP PYGGQPPHMG HHHHGHHPRG
GAGVVPFRAG DWRCGAEGCQ YHNFAKNINC LRCGAPRSGA AVVVDSSFPS PMGPPSGFGM
EPGSMGGTPG PAPYGAGAAA FGSGTAFGQP PTQYGMPSAM GAPGGAFPQM GGMTPGYASS
TMSHSSFGPA AQAAFSGAAD TTAHTMPGNG PQNGFYGNEP NADPFAFLSA GLGNLSVGDE
NQPPRRNGGP QSAKSPA
//
