ID A0A072PZL4_9EURO Unreviewed; 519 AA.
AC A0A072PZL4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=sphingolipid C(9)-methyltransferase {ECO:0000256|ARBA:ARBA00039020};
DE EC=2.1.1.317 {ECO:0000256|ARBA:ARBA00039020};
GN ORFNames=A1O9_02650 {ECO:0000313|EMBL:KEF61085.1};
OS Exophiala aquamarina CBS 119918.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; Exophiala.
OX NCBI_TaxID=1182545 {ECO:0000313|EMBL:KEF61085.1, ECO:0000313|Proteomes:UP000027920};
RN [1] {ECO:0000313|EMBL:KEF61085.1, ECO:0000313|Proteomes:UP000027920}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 119918 {ECO:0000313|EMBL:KEF61085.1,
RC ECO:0000313|Proteomes:UP000027920};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Exophiala aquamarina CBS 119918.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC {ECO:0000256|ARBA:ARBA00004760}.
CC -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC {ECO:0000256|ARBA:ARBA00010815}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEF61085.1}.
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DR EMBL; AMGV01000002; KEF61085.1; -; Genomic_DNA.
DR RefSeq; XP_013263675.1; XM_013408221.1.
DR AlphaFoldDB; A0A072PZL4; -.
DR STRING; 1182545.A0A072PZL4; -.
DR GeneID; 25277591; -.
DR VEuPathDB; FungiDB:A1O9_02650; -.
DR HOGENOM; CLU_026434_5_0_1; -.
DR OrthoDB; 5484439at2759; -.
DR Proteomes; UP000027920; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR45197:SF1; SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED; 1.
DR PANTHER; PTHR45197; SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED; 1.
DR Pfam; PF02353; CMAS; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000027920};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 55..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 519 AA; 59243 MW; 3A2323D4A514A021 CRC64;
MAKTHSESSE DFEFIETPAA ASPQLPVENY GVRTTSYPAI ANAPLPADGS GSDSFNNYVL
FALLIAVPWW VARQFHGGFY TTIFFALLTS FPILMIFWTV ASSISPRKNE KARYPGLPIE
HYLSFRSQED RDKYYGKNRI PMETFSEMYF DEKVDFKGDT LEMLEYRHDW ANFRFTMGLF
KHFFTGFIPE MLLHTRSQDE EQVRDHYDRG DDFYSWFLGP RMIYTSGIIS DINREESLEQ
LQDNKLAIVC EKIDVQPGDS MLDIGCGWGT LAKYASVNYG AKVTGVTLGR NQTAWGNNGL
RKSGITEEQS NIVCMDYRDI IVPEGGFKRI TCLEMAEHVG VRHLASFFRQ VNDMLDDDGV
FFLQIAGLRK YWQYEDLEWG LFMNKYIFPG ADASTPLGFV VDTLEGAGFE VKSIDTIGVH
YSATLWRWYR NWIANQDKVK AKYGVRWYRI WEYFLAYSTI ISRQGSATCF QITLVKNINS
THRVEGINTQ FGLSGALRAG LARLVAPKAN GASKIAKKL
//
