ID A0A073AY97_9PSEU Unreviewed; 300 AA.
AC A0A073AY97;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=beta-lactamase {ECO:0000256|ARBA:ARBA00012865};
DE EC=3.5.2.6 {ECO:0000256|ARBA:ARBA00012865};
GN ORFNames=GU90_08065 {ECO:0000313|EMBL:KEI44728.1};
OS Saccharopolyspora rectivirgula.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Saccharopolyspora.
OX NCBI_TaxID=28042 {ECO:0000313|EMBL:KEI44728.1, ECO:0000313|Proteomes:UP000031419};
RN [1] {ECO:0000313|EMBL:KEI44728.1, ECO:0000313|Proteomes:UP000031419}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43113 {ECO:0000313|EMBL:KEI44728.1,
RC ECO:0000313|Proteomes:UP000031419};
RA Barrera C., Millon L., Rognon B., Zaugg C., Monod M.;
RT "Saccharopolyspora rectivirgula DSM-43113 Genome sequencing.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a beta-lactam + H2O = a substituted beta-amino acid;
CC Xref=Rhea:RHEA:20401, ChEBI:CHEBI:15377, ChEBI:CHEBI:35627,
CC ChEBI:CHEBI:140347; EC=3.5.2.6;
CC Evidence={ECO:0000256|ARBA:ARBA00001526};
CC -!- SIMILARITY: Belongs to the class-A beta-lactamase family.
CC {ECO:0000256|ARBA:ARBA00009009}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KEI44728.1}.
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DR EMBL; JNVU01000020; KEI44728.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A073AY97; -.
DR eggNOG; COG2367; Bacteria.
DR OrthoDB; 9784149at2; -.
DR Proteomes; UP000031419; Unassembled WGS sequence.
DR GO; GO:0008800; F:beta-lactamase activity; IEA:UniProtKB-EC.
DR GO; GO:0030655; P:beta-lactam antibiotic catabolic process; IEA:InterPro.
DR GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR045155; Beta-lactam_cat.
DR InterPro; IPR000871; Beta-lactam_class-A.
DR PANTHER; PTHR35333; BETA-LACTAMASE; 1.
DR PANTHER; PTHR35333:SF3; BETA-LACTAMASE2 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13354; Beta-lactamase2; 1.
DR PRINTS; PR00118; BLACTAMASEA.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE 3: Inferred from homology;
KW Antibiotic resistance {ECO:0000256|ARBA:ARBA00023251};
KW Reference proteome {ECO:0000313|Proteomes:UP000031419}.
FT DOMAIN 59..273
FT /note="Beta-lactamase class A catalytic"
FT /evidence="ECO:0000259|Pfam:PF13354"
SQ SEQUENCE 300 AA; 32502 MW; 7080B0C18C834811 CRC64;
MDLEGEPVLP PRIWRALLAF VTILALTGCS GPESASSAGT LDAREEFSRL ERDFDARLGV
YAVDTATGRE VAYRADERFA HASTFKALAA GELLRRNSLE ELDRTITYSR DDLVTYSPIT
EKHVDSGMPL REVIAAAIRH SDNTAGNLLL RELGGPDGFT AALRRIGDTT TRADRFETDL
NETAPGDPRD TSTPRALATS LRAYAVDDVL PADKRAVLNE MLRTNTTGDA LIRASAPAGW
QVGDKTGAAS HGTRNDIAVV WPPERAPIVL AVLSDREAED ADYEDALIAR AAAVVFELLR
//
