ID A0A074VHZ7_9PEZI Unreviewed; 786 AA.
AC A0A074VHZ7;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DUF21-domain-containing protein {ECO:0000313|EMBL:KEQ60103.1};
GN ORFNames=M437DRAFT_55046 {ECO:0000313|EMBL:KEQ60103.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ60103.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ60103.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ60103.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL584844; KEQ60103.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074VHZ7; -.
DR STRING; 1043003.A0A074VHZ7; -.
DR HOGENOM; CLU_011310_3_0_1; -.
DR OrthoDB; 248389at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR InterPro; IPR045095; ACDP.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR002550; CNNM.
DR InterPro; IPR044751; Ion_transp-like_CBS.
DR PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR PANTHER; PTHR12064:SF100; PROTEIN MAM3; 1.
DR Pfam; PF01595; CNNM; 1.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR PROSITE; PS51371; CBS; 1.
DR PROSITE; PS51846; CNNM; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU01193};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW ProRule:PRU01193}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..786
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001702047"
FT TRANSMEM 52..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 48..234
FT /note="CNNM transmembrane"
FT /evidence="ECO:0000259|PROSITE:PS51846"
FT DOMAIN 315..380
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT REGION 425..546
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..599
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 611..630
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..669
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..748
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..764
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 772..786
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 786 AA; 84505 MW; B1D895302D055A3E CRC64;
MTPAALSIVK LLGVSLINLP LSYAAPLFSN KSDSPIYRRE EPEPKSPDDP QLWVYLGVAI
ALVLLGGVFA GLTIALMGQD EIYLQVIATS GEGSEKKSAA KVLRLLKKGK HWVLVTLLLS
NVITNETLPI VLDRSLGGGW PAVLSSTILI VIFGEVVPQS ICVRFGLPIG AAMSPLVLGL
MWIMAPVAWP TAKLLDWLLG EDHGTVYKKA GLKTLVTLHK TLGTSPSDRL NEDEVTIISA
VLDLKDKPVG DIMTPMGDVF TMSADTVLDE KMMDTILSQG YSRIPIYAPD NTRNFIGMLL
VKILITYDPE DALRVRDFAL ATLPETKPET SCLDIVNFFQ EGKSHMVLVS DFPGQDKGAL
GVVTLEDVIE ELIGEEIIDE SDVFVDVHKA IRRIAPAPRT RYNRGNLVVD APATDDDTDV
DERTHLLGHK DSSSQSRKSS LTGSREATLL LRRRSSTSSD KNRPLPIRSN TADLRQHLKH
LGPSNVASRP KATKYTSVKI KPGVGTIPEN HVPAPASTQG PESSQTGTPQ TVVNGNSSRP
EGGIGAGLIG SAALEAQDGA HAVAHGYGTI SPGSKNPSVH EESEVQAENN STSPKPMTAS
EASAFADGHT GTKPESKENH GHEQEQQNGN HESSEQEQPD LPQKLVVQGS TSRPISRDRR
GSGSSHSTLG EMEDRPGYKS RRAVRSGSIT ENIIDVNGMK KVVLEANSSS DGDEQKAAEA
SDGANDKRGH DEDQDDAGHD DAGHDDSKGT KKKKKKKRAG KKFRNKGDSV KSRSGDSTPL
LSQGDR
//
