ID A0A074VSY4_9PEZI Unreviewed; 878 AA.
AC A0A074VSY4;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=M437DRAFT_66231 {ECO:0000313|EMBL:KEQ62354.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ62354.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ62354.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ62354.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL584834; KEQ62354.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074VSY4; -.
DR STRING; 1043003.A0A074VSY4; -.
DR HOGENOM; CLU_327597_0_0_1; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 734..755
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 300..454
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 124..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 845..878
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..22
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 878 AA; 97626 MW; D07FBE365250752C CRC64;
MTEPEDHLAP ASRCEVPRDR QRNRVAPASS NESSLLTRTE SSPEGLHGFE PVYGLPELSV
TALRRAGIEK LLPSQKHVLE SVQFIENRRA DHHRVIISRF AAGKTTLICL ASFVAVMRCS
AGDSQPPTFK ESPSSAELPP AAPPSENSYN TRHSSAVAKP LVLIVVPFPE NARDAGVFLE
QLLKCHGNSY AAIVGDELAE ADFTALRKWP TAVIGTFDRL LGLVEHGYLN LSQLVYLAID
DLDTCLQDVT FNSFLQFLHE NLPECQVIIT SSCMTLDLVI PVLTLIGQSS PIPAVVRMGR
IPKDSTTFEE GKVLMCGETP DGVEKIYRLF DDYLKTNGCS DIDKYIRLAH HHHQTEAERR
ITLEQLRKDD FCMLITTYKF ARAVHIPNVN TAINIHPAKD LDVYRKVCNR VGREGRGLIC
TLYGEEDMES VEQYKRVFNT KNDYSLVIDG EVVPPNGMRE MTSMELLKEF GNAREAHRRK
RFTTGVAGGV LIWASLAAYV AQPSNAAGQS SRVARLINGV ARIAGNVANN NKKKEGALSR
EVHTTFLEAG RKATPKTSNK RKATTDQASE YMNLSPTKDG LEWQAVWAAI VEKQPLNKVT
NKPFVWLENI TKVLMFMWSS PQGVDCVLKM VEAVYRDFDT LKLDAITSAS NSKSSVYTLE
MRYKRVLSLS KAAALQTAEL LLEYKNMADD FVRLEQQTQD PSTELGKEWA KRETNANKET
TDQTRSNVAI KLRVYVRSIA IMIAIFGWGV VPLLACATWK FADVSNASAH ACLQELANAV
PMLRQVCDRL DKNFYRFLRI PGQITQLPKY CLQGMSVKKQ DRLSYTIAYH LAAPGEREEL
GGMLNVKSPS HAGQKKTSIT GQKGAKGAKG GKGRKKVF
//
