ID A0A074VY20_9PEZI Unreviewed; 622 AA.
AC A0A074VY20;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Anaphase-promoting complex subunit 2 {ECO:0000256|ARBA:ARBA00016068};
GN ORFNames=M437DRAFT_44857 {ECO:0000313|EMBL:KEQ64129.1};
OS Aureobasidium melanogenum CBS 110374.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043003 {ECO:0000313|EMBL:KEQ64129.1, ECO:0000313|Proteomes:UP000030672};
RN [1] {ECO:0000313|EMBL:KEQ64129.1, ECO:0000313|Proteomes:UP000030672}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 110374 {ECO:0000313|EMBL:KEQ64129.1,
RC ECO:0000313|Proteomes:UP000030672};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000256|PROSITE-
CC ProRule:PRU00330, ECO:0000256|RuleBase:RU003829}.
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DR EMBL; KL584829; KEQ64129.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074VY20; -.
DR STRING; 1043003.A0A074VY20; -.
DR HOGENOM; CLU_007149_0_1_1; -.
DR OrthoDB; 2786196at2759; -.
DR Proteomes; UP000030672; Unassembled WGS sequence.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR044554; APC2-like.
DR InterPro; IPR014786; APC2_C.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR45957; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR PANTHER; PTHR45957:SF1; ANAPHASE-PROMOTING COMPLEX SUBUNIT 2; 1.
DR Pfam; PF08672; ANAPC2; 1.
DR Pfam; PF00888; Cullin; 1.
DR SMART; SM01013; APC2; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Reference proteome {ECO:0000313|Proteomes:UP000030672};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT DOMAIN 222..503
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 622 AA; 70139 MW; CBAB7A8BF5D99457 CRC64;
MDVFVQSAAM KVDWTQRQSV VDRLRQWIRH RFVPAVGLST PNELADWENT ALERLAKQRI
RHLLDYVKAW PHSTGAILDL KECMHSSDVK IQIATSFTRQ LSRRLLHAGV TTSELLSIYI
NVIMAFKTLD PRGVLLDKVA VPLRAYLRHR EDTVRIIAAS FLADVGEDDG SLDNSSEEIC
VDLAREINLS EGQALHVEHK GLDWDDMEWM PDPIDAGPDY KKSKSEDVMS FMLTLFEQAD
FIKEVQSLLG ERLLSVGYDD TELEKEIRLV ELFKTRFGAD RLQSCEVMLR DIQDSRRINN
TLRPKDDFPT AQEVHAAIPD TGIKSQALIG MFNTRVPRTD LAGHKFIALI KSVAVAEKGS
DILYPSPDLP MFESSVDTEL SAAFQTQILS SFFWPSLRED EFAVPAPIST LQKNFEQDFE
RIKNLRKLHW LSALGKATVE LELEDRTVKF EGVQTWQASV IYAFQDDSED ASTVSPASRT
VQQLEELLQM EEVLVRNALA FWVGHQVLVE DEPDVFTVLE QLPSADRKAA TAPSAPVQAD
NVISAVKSQD AVLQDNKPMY EMFMMGMLTN GGAMDAARIT MMMKMVVPGG YNFGEDETRW
LLSGMEEQGK VVVNGSNYSI KK
//
