ID A0A074YLT1_AURPU Unreviewed; 881 AA.
AC A0A074YLT1;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=DUF221-domain-containing protein {ECO:0000313|EMBL:KEQ87856.1};
GN ORFNames=M438DRAFT_133717 {ECO:0000313|EMBL:KEQ87856.1};
OS Aureobasidium pullulans EXF-150.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Dothideales; Saccotheciaceae; Aureobasidium.
OX NCBI_TaxID=1043002 {ECO:0000313|EMBL:KEQ87856.1, ECO:0000313|Proteomes:UP000030706};
RN [1] {ECO:0000313|EMBL:KEQ87856.1, ECO:0000313|Proteomes:UP000030706}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EXF-150 {ECO:0000313|EMBL:KEQ87856.1,
RC ECO:0000313|Proteomes:UP000030706};
RX PubMed=24984952;
RA Gostin Ar C., Ohm R.A., Kogej T., Sonjak S., Turk M., Zajc J., Zalar P.,
RA Grube M., Sun H., Han J., Sharma A., Chiniquy J., Ngan C.Y., Lipzen A.,
RA Barry K., Grigoriev I.V., Gunde-Cimerman N.;
RT "Genome sequencing of four Aureobasidium pullulans varieties:
RT biotechnological potential, stress tolerance, and description of new
RT species.";
RL BMC Genomics 15:549-549(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
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DR EMBL; KL584976; KEQ87856.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A074YLT1; -.
DR HOGENOM; CLU_002458_2_1_1; -.
DR OrthoDB; 54187at2759; -.
DR Proteomes; UP000030706; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR022257; PHM7_ext.
DR PANTHER; PTHR13018:SF26; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_5G10920)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF12621; PHM7_ext; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030706};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 28..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 514..541
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 561..590
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 611..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..657
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 678..697
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..177
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 200..396
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 410..693
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT DOMAIN 782..873
FT /note="10TM putative phosphate transporter extracellular
FT tail"
FT /evidence="ECO:0000259|Pfam:PF12621"
FT COILED 238..285
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 881 AA; 98933 MW; C6279945B832A4D1 CRC64;
MAATSATDAN DDPNVGSAQN VSSSATGLLS TLAPVAVLAL VWFTLFLIFR RWFPRNYRPR
TFLGSIQERE RSPKLPDGIF AWFSNFFNMP DSYVLNHHSL DGYLFLRLLK MAVITCLVGC
CITFPILFPI NITGGGGKSQ LDILTLGNVT NNYYMMFAHV GCAYLFFGFV IYMITRESIY
YINLRQAYLL SPYYASRLSS RTVLFTSVPD EYLHETNLRR MLGESVERVW IPTDTGDLED
EVKERDKTAL KLEAAETKLI KAANAARLKA TKKKAKKDNE DIALEELTPD VEGGSAASRY
ISAKDRPTHR LKFLIGKKVD TIDWCRAELE KRIPEVAAMQ EKHRALDGIK KINSVFVQFT
TLQEAQSAYQ SLTHHQVLHM APRYTGMTPG EIIWSNLRIK WWERVLRVTA TVSFVVALIV
FWSFPVAAVG FISNLDNLKD YSTGNPPTTF KEGFTWLNWL LALPPQIFGV VSGLLPTVAL
AILMSVLPII LRLMARLGGD PSLSAVELTV QNTYFGFQIV QVFLVATLGS AASSALGSIL
PNHIDQIPTL LASSIPKASN FYLSYFVLQG LGVVSGTLLN LSGLVIFIIL GKFLDNTPRK
MYKRWTSLSS MSWGTVFPPY TNLFVIAICY AIIAPLVMLF AAIGLYLFYL AYRYNLLYVS
NANIDTKGRV YPRALQQVFV GLYVAEGCLV GLFAIATGSS VGALGPLILM IVFLVFTALY
HLSLNAALEP LINYLPKSLE AEERRLLDED VEEERGEKGM VADRRTELGP SPHGKPSFWK
KFLRPDIYTD YATMRRLVPK MINIRYEEEE ENHAYYNPAV TAAPHLLWIP RDPMGVSRQE
VRDTSKVIPI TDEGATLDEK NKVVWDAEDG RPPIWERPVY Y
//
