ID A0A074ZV07_9TREM Unreviewed; 1144 AA.
AC A0A074ZV07;
DT 01-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 01-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Serine/threonine-protein kinase ULK3 {ECO:0000256|ARBA:ARBA00021644};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
DE AltName: Full=Unc-51-like kinase 3 {ECO:0000256|ARBA:ARBA00032242};
DE Flags: Fragment;
GN ORFNames=T265_13065 {ECO:0000313|EMBL:KER30986.1};
OS Opisthorchis viverrini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Opisthorchiida; Opisthorchiata; Opisthorchiidae; Opisthorchis.
OX NCBI_TaxID=6198 {ECO:0000313|EMBL:KER30986.1, ECO:0000313|Proteomes:UP000054324};
RN [1] {ECO:0000313|EMBL:KER30986.1, ECO:0000313|Proteomes:UP000054324}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Young N.D., Nagarajan N., Lin S.J., Korhonen P.K., Jex A.R., Hall R.S.,
RA Safavi-Hemami H., Kaewkong W., Bertrand D., Gao S., Seet Q., Wongkham S.,
RA Teh B.T., Wongkham C., Intapan P.M., Maleewong W., Yang X., Hu M., Wang Z.,
RA Hofmann A., Sternberg P.W., Tan P., Wang J., Gasser R.B.;
RT "Opisthorchis viverrini - life in the bile duct.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; KL596652; KER30986.1; -; Genomic_DNA.
DR RefSeq; XP_009165281.1; XM_009167017.1.
DR AlphaFoldDB; A0A074ZV07; -.
DR STRING; 6198.A0A074ZV07; -.
DR GeneID; 20327233; -.
DR KEGG; ovi:T265_13065; -.
DR CTD; 20327233; -.
DR OrthoDB; 8335at2759; -.
DR Proteomes; UP000054324; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
DR GO; GO:0010506; P:regulation of autophagy; IEA:InterPro.
DR Gene3D; 1.20.58.80; Phosphotransferase system, lactose/cellobiose-type IIA subunit; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR045269; Atg1-like.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR007330; MIT_dom.
DR InterPro; IPR036181; MIT_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR24348; SERINE/THREONINE-PROTEIN KINASE UNC-51-RELATED; 1.
DR PANTHER; PTHR24348:SF65; SERINE_THREONINE-PROTEIN KINASE ULK3; 1.
DR Pfam; PF04212; MIT; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00745; MIT; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF116846; MIT domain; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054324}.
FT DOMAIN 209..475
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 553..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 664..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 882..903
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 916..947
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1072..1097
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..611
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 664..695
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..735
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1072..1088
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KER30986.1"
FT NON_TER 1144
FT /evidence="ECO:0000313|EMBL:KER30986.1"
SQ SEQUENCE 1144 AA; 126632 MW; 3F8B18356991DB48 CRC64;
RSEIRQNGRR EKTFEALLTS GTSVRGTTQG HFFTRDPAAN FPWPQPQLYP TPCEQVSLLE
DAENAGNLRK LFRMIRSAEA SCQRNYQGPE WLPDIQQSTT FEPLGRVIQT AIQLAPSSVR
NFGLQQKEVS ECITLLKRYR APGVDLLPTL FKDSGVCLSQ CLCGRFGSIW EKKTVPDNVF
GLLVFGFDVS TTDWHAEVGE LGMLKLPNFS VLRRLGRGSY GEVYLIRKQV TDSHKDACSQ
GSDQLIAVKC IPRQKLSKRG EDNLVSEISI LQKLSHPHIV RMLDFSWDDR SVFLFMEYCA
GGDLSDFLHA KNRLPEPLVR RFLRQMALAL QYLKEKNIIH MDLKPQNILL TSSTNPVLKV
TDFGFAKRTK DTIQLNELRG TLLYMAPEVY CEGIYHPSCD LWSIGIILFE CLFGNPPYAS
EDSKQLKAKL LTAKPIVIPS DPRISANCAA LLRGLLKRNP EERMNHTEFF EHPFVDIKHA
PSAESLDKAL SHLEKARMLE KKNDLEAAYE YYTHGLAHLV SAVEYETSTS QRELLKQLAS
QYFTQAEAVK TRLKVEGSRT GNSVPPRPPP PWKRGQNRHS CQTETSVHPK NVPTVAGTEK
RINTSASLAR AQMVPPATPP TPQISSQMGS ELDSESTPSS PSSGLLTYLK SLFIASHGCG
SEQSAGLTAE TQTPGKQQAS THPSSSEVSS QPPPFTQCPK TDPVGQPIIA SREVAQTSEQ
GPSHTRGSTS SGKKLTLSTK EVHMKNRAPK QRFPVPSATL DPLNYPLDKA SHLDEGRQAC
SLPSFCPPAT TGSPSASASC SGTTSSVCHE EAGGLVCKPI RATNKSRPRR NLWVRAFHLL
SNRLKFKLKP WRVVDYPAQS NSDQPVGFSS SSSTLRLSSG MAAPYDSASD APNAQLERSK
SRWSGRVAHS ETLVCPTITK SPPPTRDMSS VDPEEKPLRS QEGSSLRRMQ RVRALSMDIN
SSPCTHPDDV DSNVASAPTY AQQMALLADT ARLFELKAMC ADSDTNCLQL IEWLEEFYSL
LRTGRLHQAL KHSEDNFAEY LQIAKADTND ARRSSFLKEL KLVLDLMESG KQQQTAVSNE
SPHSTERHSV SPVPEEVGVE VTPEAGKSIV DKYLRTILCS GPSVILSQPP RIHKGTLNYS
VSQL
//
