ID A0A075JPD2_9BACI Unreviewed; 677 AA.
AC A0A075JPD2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093,
GN ECO:0000313|EMBL:AIF43744.1};
GN ORFNames=X953_11855 {ECO:0000313|EMBL:AIF43744.1};
OS Virgibacillus sp. SK37.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX NCBI_TaxID=403957 {ECO:0000313|EMBL:AIF43744.1, ECO:0000313|Proteomes:UP000027985};
RN [1] {ECO:0000313|EMBL:AIF43744.1, ECO:0000313|Proteomes:UP000027985}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK37 {ECO:0000313|EMBL:AIF43744.1,
RC ECO:0000313|Proteomes:UP000027985};
RA Phrommao E., Yongsawatdigul J., Rodtong S., Steele J.L.;
RT "Complete genome sequence of Virgibacillus sp. SK37, a moderately
RT halophilic bacterium isolated from Thai fish sauce fermentation.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
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DR EMBL; CP007161; AIF43744.1; -; Genomic_DNA.
DR RefSeq; WP_040955654.1; NZ_CP007161.1.
DR AlphaFoldDB; A0A075JPD2; -.
DR STRING; 403957.X953_11855; -.
DR KEGG; vir:X953_11855; -.
DR HOGENOM; CLU_015346_3_0_9; -.
DR OrthoDB; 9759185at2; -.
DR Proteomes; UP000027985; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR025505; FHIPEP_CS.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
DR PROSITE; PS00994; FHIPEP; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:AIF43744.1};
KW Cilium {ECO:0000313|EMBL:AIF43744.1};
KW Flagellum {ECO:0000313|EMBL:AIF43744.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Reference proteome {ECO:0000313|Proteomes:UP000027985};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 6..23
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 30..47
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 93..119
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 229..251
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 271..300
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 677 AA; 74540 MW; F8894D068D586998 CRC64;
MKARDLSVLL GVILIIIMLI IPLPGWLLSV LILSNISIAL IVILVSMNTQ EALQFSVFPT
LLLLLTLFRL GLNVSTTRSI LSEAQAGGVV ETFGSFVIGG NPLVGFVVFI ILVIIQFLVI
TKGAERVSEV SARFTLDAMP GKQMSIDADL NAGLISEQQA KERREKVENE ADFHGSMDGA
SKFVKGDAIA GIIIVLINIV FGLIIGMVQM DMTFQEAINT FMRLTVGDGL VSQIPALLIS
TATGIVVTRT ASTGNLGTEV SGQLLQYPKL LFIAAGTIFL LGLTPINFFL TTLLAGLLAL
SGYLLLRQTA EPDIPDPEEE DLTESSSMKS SENVVSLLNM DPIEFEFGYA LIPLADSSQG
GDLLDRIIMI RRQLAIELGI VIPVVRIRDN IQLNPNEYRL KIKGNEVATG ELLLDHYLAM
APDIEEDNME GIATKEPAFG LPAKWITEEY KDEAELSGYT VVDPPSVVST HITEIIKKYA
YILLGREETK QLIEHLRESY PTLAEEVTPD PLSVGDVQKV LSKLLKENIS IRNLPVIFES
LADFAKLTND TELLAEYVRQ ALSPQITKQY VHEDMSLRVI TVSGKIEKMI AENIQQTEHG
NYLSLDPEMQ QEIIKTIHQE VEKLAIQEET AILLCSPAIR MYLKQLVERF LPQVVVLSYN
ELEPTVEVQS VGVVNIA
//
