UniProt: A0A075R376

Database: UniProt
Entry: A0A075R376_BRELA

LinkDB:  A0A075R376_BRELA 
Original site:  A0A075R376_BRELA

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Ontology (3)   
   GO (3)   
Gene (1)   
   KEGG GENES (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (5)   
   InterPro (4)   
   Pfam (1)   
Literature (1)   
   PubMed (1)   
All databases (12)   

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ID   A0A075R376_BRELA        Unreviewed;       325 AA.
AC   A0A075R376;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 37.
DE   RecName: Full=Magnesium transport protein CorA {ECO:0000256|RuleBase:RU362010};
GN   Name=corA_1 {ECO:0000313|EMBL:AIG25623.1};
GN   Synonyms=corA {ECO:0000256|RuleBase:RU362010};
GN   ORFNames=BRLA_c012830 {ECO:0000313|EMBL:AIG25623.1};
OS   Brevibacillus laterosporus LMG 15441.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Brevibacillus.
OX   NCBI_TaxID=1042163 {ECO:0000313|EMBL:AIG25623.1, ECO:0000313|Proteomes:UP000005850};
RN   [1] {ECO:0000313|EMBL:AIG25623.1, ECO:0000313|Proteomes:UP000005850}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LMG 15441 {ECO:0000313|EMBL:AIG25623.1,
RC   ECO:0000313|Proteomes:UP000005850};
RX   PubMed=21914864; DOI=10.1128/JB.05696-11;
RA   Djukic M., Poehlein A., Thurmer A., Daniel R.;
RT   "Genome sequence of Brevibacillus laterosporus LMG 15441, a pathogen of
RT   invertebrates.";
RL   J. Bacteriol. 193:5535-5536(2011).
CC   -!- FUNCTION: Mediates influx of magnesium ions.
CC       {ECO:0000256|RuleBase:RU362010}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC       ECO:0000256|RuleBase:RU362010}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362010}.
CC   -!- SIMILARITY: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35)
CC       family. {ECO:0000256|ARBA:ARBA00009765, ECO:0000256|RuleBase:RU362010}.
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DR   EMBL; CP007806; AIG25623.1; -; Genomic_DNA.
DR   RefSeq; WP_003338347.1; NZ_CP007806.1.
DR   AlphaFoldDB; A0A075R376; -.
DR   STRING; 1042163.BRLA_c012830; -.
DR   KEGG; blr:BRLA_c012830; -.
DR   eggNOG; COG0598; Bacteria.
DR   HOGENOM; CLU_007127_0_0_9; -.
DR   Proteomes; UP000005850; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015087; F:cobalt ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   CDD; cd12822; TmCorA-like; 1.
DR   Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR   Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 2.
DR   InterPro; IPR045861; CorA_cytoplasmic_dom.
DR   InterPro; IPR045863; CorA_TM1_TM2.
DR   InterPro; IPR004488; Mg/Co-transport_prot_CorA.
DR   InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR   NCBIfam; TIGR00383; corA; 1.
DR   PANTHER; PTHR46494; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   PANTHER; PTHR46494:SF1; CORA FAMILY METAL ION TRANSPORTER (EUROFUNG); 1.
DR   Pfam; PF01544; CorA; 1.
DR   SUPFAM; SSF143865; CorA soluble domain-like; 1.
DR   SUPFAM; SSF144083; Magnesium transport protein CorA, transmembrane region; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU362010};
KW   Ion transport {ECO:0000256|RuleBase:RU362010};
KW   Magnesium {ECO:0000256|RuleBase:RU362010};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362010};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005850};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU362010};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU362010}; Transport {ECO:0000256|RuleBase:RU362010}.
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
FT   TRANSMEM        298..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU362010"
SQ   SEQUENCE   325 AA;  38242 MW;  04D73250573EA25E CRC64;
     MIKTYFYNHS EQKMIHDVDL TTKDQWLKSP EDLLWIDLYD VGNQELHYIA KIFEFHPLAI
     EDCLHVSPRA KVDKYDDYYF FVFHALRYNE ESDNEITTVE LNVFLGPNYI VTIHKSPMNT
     IGRIAAQCHR SNSFLNRGPD YLLYAIVDGI TDEYFPIMDR LSVRIDDLED EIYEHQTEEI
     TEEFLALKRT LILIRRVILP QKRIFANVNG RYSFDISEEN VPFYVDLTDH LERIVDSTET
     FRDLVNGALD TYYTIITGRS NETVRILTII STVILPLTFI TGIFGMNTFE WMGDKAEPVM
     FVIAFGSMIL LTSWMLYVFK KKKWL
//

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