ID A0A076MN58_AMYME Unreviewed; 353 AA.
AC A0A076MN58;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:AIJ22283.1};
GN Name=lacI {ECO:0000313|EMBL:AIJ22283.1};
GN ORFNames=AMETH_2191 {ECO:0000313|EMBL:AIJ22283.1};
OS Amycolatopsis methanolica 239.
OC Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC Pseudonocardiaceae; Amycolatopsis; Amycolatopsis methanolica group.
OX NCBI_TaxID=1068978 {ECO:0000313|EMBL:AIJ22283.1, ECO:0000313|Proteomes:UP000062973};
RN [1] {ECO:0000313|EMBL:AIJ22283.1, ECO:0000313|Proteomes:UP000062973}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=239 {ECO:0000313|EMBL:AIJ22283.1,
RC ECO:0000313|Proteomes:UP000062973};
RA Tang B.;
RT "Whole Genome Sequence of the Amycolatopsis methanolica 239.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP009110; AIJ22283.1; -; Genomic_DNA.
DR RefSeq; WP_017981499.1; NZ_CP009110.1.
DR AlphaFoldDB; A0A076MN58; -.
DR STRING; 1068978.AMETH_2191; -.
DR KEGG; amq:AMETH_2191; -.
DR PATRIC; fig|1068978.7.peg.2330; -.
DR eggNOG; COG1609; Bacteria.
DR HOGENOM; CLU_037628_6_1_11; -.
DR OrthoDB; 59108at2; -.
DR Proteomes; UP000062973; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR PANTHER; PTHR30146:SF109; TRANSCRIPTIONAL REGULATOR LACI_GALR-LIKE SENSOR DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000062973};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..60
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 353 AA; 37230 MW; 77BB2AAAFCEBC5E9 CRC64;
MTTHGASLID VARAAGVSTA TAGRALGGYG QVSERTRERV LAAAAELGYR PNGLARSMVT
GSTQTIGVVV TDVANPFFAT ALRGITDVTS PAGFEVLLAN TGGVLEAEQR AVSVMSEKRV
DGVIVAAARP GEGAHLRRAM DAGVPVVLID RQVSGVPEAD SITVDNDHAA AEAVGHLTEL
GHRRIGVITE AGDQLARVRT GNRRRGLFPS AVRLRGYVSA LEAAGLPVDA GLVASARYDR
ESAYDAMNRL LDLPEPPTAV LCTDNVLASG AYRAAQDRGL RMPTQLSLIG FDDEPWTTLV
RPELTIVEQP TYDLGARAGR QLLDRIADGA APRRPQHIQL RAKLVARGST VPR
//
