ID A0A076NR84_9CORY Unreviewed; 310 AA.
AC A0A076NR84;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=rRNA methylase {ECO:0000313|EMBL:SNV82878.1};
DE EC=2.1.1.- {ECO:0000313|EMBL:SNV82878.1};
DE SubName: Full=rRNA methyltransferase {ECO:0000313|EMBL:AIJ34195.1};
GN ORFNames=CIMIT_10130 {ECO:0000313|EMBL:AIJ34195.1}, SAMEA4535761_02086
GN {ECO:0000313|EMBL:SNV82878.1};
OS Corynebacterium imitans.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales;
OC Corynebacteriaceae; Corynebacterium.
OX NCBI_TaxID=156978 {ECO:0000313|EMBL:AIJ34195.1, ECO:0000313|Proteomes:UP000028780};
RN [1] {ECO:0000313|EMBL:AIJ34195.1, ECO:0000313|Proteomes:UP000028780}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44264 {ECO:0000313|EMBL:AIJ34195.1,
RC ECO:0000313|Proteomes:UP000028780};
RA Mollmann S., Albersmeier A., Ruckert C., Tauch A.;
RT "Complete genome sequence of Corynebacterium imitans DSM 44264, isolated
RT from a five-month-old boy with suspected pharyngeal diphtheria.";
RL Submitted (AUG-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SNV82878.1, ECO:0000313|Proteomes:UP000215374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13015 {ECO:0000313|EMBL:SNV82878.1,
RC ECO:0000313|Proteomes:UP000215374};
RG Pathogen Informatics;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class IV-like SAM-binding methyltransferase
CC superfamily. RNA methyltransferase TrmH family.
CC {ECO:0000256|ARBA:ARBA00007228}.
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DR EMBL; CP009211; AIJ34195.1; -; Genomic_DNA.
DR EMBL; LT906467; SNV82878.1; -; Genomic_DNA.
DR RefSeq; WP_038592398.1; NZ_LT906467.1.
DR AlphaFoldDB; A0A076NR84; -.
DR STRING; 156978.CIMIT_10130; -.
DR KEGG; cii:CIMIT_10130; -.
DR eggNOG; COG0566; Bacteria.
DR HOGENOM; CLU_021322_0_0_11; -.
DR OrthoDB; 9785673at2; -.
DR Proteomes; UP000028780; Chromosome.
DR Proteomes; UP000215374; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0008173; F:RNA methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd18103; SpoU-like_RlmB; 1.
DR Gene3D; 3.30.1330.30; -; 1.
DR Gene3D; 3.40.1280.10; -; 1.
DR InterPro; IPR029028; Alpha/beta_knot_MTases.
DR InterPro; IPR029064; Ribosomal_eL30-like_sf.
DR InterPro; IPR004441; rRNA_MeTrfase_TrmH.
DR InterPro; IPR001537; SpoU_MeTrfase.
DR InterPro; IPR013123; SpoU_subst-bd.
DR InterPro; IPR029026; tRNA_m1G_MTases_N.
DR NCBIfam; TIGR00186; rRNA_methyl_3; 1.
DR PANTHER; PTHR46429; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR PANTHER; PTHR46429:SF1; 23S RRNA (GUANOSINE-2'-O-)-METHYLTRANSFERASE RLMB; 1.
DR Pfam; PF00588; SpoU_methylase; 1.
DR Pfam; PF08032; SpoU_sub_bind; 1.
DR SMART; SM00967; SpoU_sub_bind; 1.
DR SUPFAM; SSF75217; alpha/beta knot; 1.
DR SUPFAM; SSF55315; L30e-like; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000313|EMBL:AIJ34195.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000028780};
KW Transferase {ECO:0000313|EMBL:AIJ34195.1}.
FT DOMAIN 69..145
FT /note="RNA 2-O ribose methyltransferase substrate binding"
FT /evidence="ECO:0000259|SMART:SM00967"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 310 AA; 33573 MW; DFB17A73920CED7F CRC64;
MAKPYQRPDK QKTHKKGATK GSGGQRRRGL RGKGATPKAE DRVYHAAHKR KQARDRRNQG
RHEREVADMV VGRNPVIECL HAKVPAEALY VAQGTGHDDR LSEAVAIAQS RGIPVSEVQK
RTLDEMTGNG MHQGIGLKIQ PYKYADVFDL MSRVDGNGMF VVLDNITDPR NLGAVIRSAA
AFGGDGVIIP ERRSAQVTGV AWRTSAGTAA RLPVAKATNL TRTIKQFKDN GYMVVGLDAG
GEHTLDTFDG ACDPVVIVVG SEGKGISRLV RENCDVIMSI PTEEWVESLN ASVAAGVVLS
EFARQRRAAK
//
