ID A0A077F4H2_9PSED Unreviewed; 111 AA.
AC A0A077F4H2;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 49.
DE RecName: Full=Glutaredoxin {ECO:0000256|PIRNR:PIRNR005894};
GN Name=grxD {ECO:0000313|EMBL:QGW76299.1};
GN ORFNames=DM813_14710 {ECO:0000313|EMBL:RWU22424.1}, GPJ81_06270
GN {ECO:0000313|EMBL:QGW76299.1}, PSAKL28_11410
GN {ECO:0000313|EMBL:AIL60367.1};
OS Pseudomonas alkylphenolica.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=237609 {ECO:0000313|EMBL:AIL60367.1};
RN [1] {ECO:0000313|EMBL:AIL60367.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KL28 {ECO:0000313|EMBL:AIL60367.1};
RA Lee K., Lim J.Y., Hwang I.;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RWU22424.1, ECO:0000313|Proteomes:UP000288983}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XwS2 {ECO:0000313|EMBL:RWU22424.1}, and xwS2
RC {ECO:0000313|Proteomes:UP000288983};
RA Wei X., Chunhua H.;
RT "Bacteria isolated from soil of Wuhan.";
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QGW76299.1, ECO:0000313|Proteomes:UP000426235}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Neo {ECO:0000313|EMBL:QGW76299.1,
RC ECO:0000313|Proteomes:UP000426235};
RA Ne Ville C.J., Enright D., Hernandez I., Dodsworth J., Orwin P.M.;
RT "Hybrid Genome Assemblies of two High G+C Isolates from Undergraduate
RT Microbiology Courses.";
RL Submitted (DEC-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glutaredoxin family. Monothiol subfamily.
CC {ECO:0000256|ARBA:ARBA00009630, ECO:0000256|PIRNR:PIRNR005894}.
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DR EMBL; CP009048; AIL60367.1; -; Genomic_DNA.
DR EMBL; CP046621; QGW76299.1; -; Genomic_DNA.
DR EMBL; QJRG01000044; RWU22424.1; -; Genomic_DNA.
DR RefSeq; WP_028943477.1; NZ_QJRG01000044.1.
DR AlphaFoldDB; A0A077F4H2; -.
DR STRING; 237609.PSAKL28_11410; -.
DR KEGG; palk:PSAKL28_11410; -.
DR eggNOG; COG0278; Bacteria.
DR HOGENOM; CLU_026126_2_1_6; -.
DR OrthoDB; 9804115at2; -.
DR Proteomes; UP000028931; Chromosome.
DR Proteomes; UP000288983; Unassembled WGS sequence.
DR Proteomes; UP000426235; Chromosome.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd03028; GRX_PICOT_like; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR002109; Glutaredoxin.
DR InterPro; IPR033658; GRX_PICOT-like.
DR InterPro; IPR014434; Monothiol_GRX.
DR InterPro; IPR004480; Monothiol_GRX-rel.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR NCBIfam; TIGR00365; Grx4 family monothiol glutaredoxin; 1.
DR PANTHER; PTHR10293; GLUTAREDOXIN FAMILY MEMBER; 1.
DR PANTHER; PTHR10293:SF72; MONOTHIOL GLUTAREDOXIN-S14, CHLOROPLASTIC; 1.
DR Pfam; PF00462; Glutaredoxin; 1.
DR PIRSF; PIRSF005894; Monothiol_GRX; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51354; GLUTAREDOXIN_2; 1.
PE 3: Inferred from homology;
KW 2Fe-2S {ECO:0000256|ARBA:ARBA00022714, ECO:0000256|PIRSR:PIRSR005894-2};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR005894-2};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|PIRSR:PIRSR005894-
KW 2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR005894-2}.
FT DOMAIN 16..80
FT /note="Glutaredoxin"
FT /evidence="ECO:0000259|Pfam:PF00462"
FT BINDING 21
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
FT BINDING 29
FT /ligand="[2Fe-2S] cluster"
FT /ligand_id="ChEBI:CHEBI:190135"
FT /ligand_note="ligand shared between dimeric partners"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-2"
FT BINDING 58
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
FT BINDING 70
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
FT BINDING 83..84
FT /ligand="glutathione"
FT /ligand_id="ChEBI:CHEBI:57925"
FT /evidence="ECO:0000256|PIRSR:PIRSR005894-1"
SQ SEQUENCE 111 AA; 11963 MW; D1260176EE619AC6 CRC64;
MDIIETIKEQ IANNTILLYM KGSPNAPQCG FSAKAAQAVM GCGEKFAYVD ILQNPEIRAN
LPKYANWPTF PQLWVAGELV GGSDIMAEMF ANGELQTLIK EAAAKAEAAK A
//
