ID A0A077M903_9MICO Unreviewed; 487 AA.
AC A0A077M903;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Penicillin-binding protein A {ECO:0000313|EMBL:CCH80524.1};
GN Name=pbpA {ECO:0000313|EMBL:CCH80524.1};
GN ORFNames=BN12_990010 {ECO:0000313|EMBL:CCH80524.1};
OS Tetrasphaera japonica T1-X7.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Intrasporangiaceae;
OC Tetrasphaera.
OX NCBI_TaxID=1194083 {ECO:0000313|EMBL:CCH80524.1, ECO:0000313|Proteomes:UP000035721};
RN [1] {ECO:0000313|EMBL:CCH80524.1, ECO:0000313|Proteomes:UP000035721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T1-X7 {ECO:0000313|EMBL:CCH80524.1,
RC ECO:0000313|Proteomes:UP000035721};
RX PubMed=23178666; DOI=10.1038/ismej.2012.136;
RA Kristiansen R., Nguyen H.T.T., Saunders A.M., Nielsen J.L., Wimmer R.,
RA Le V.Q., McIlroy S.J., Petrovski S., Seviour R.J., Calteau A.,
RA Nielsen K.L., Nielsen P.H.;
RT "A metabolic model for members of the genus Tetrasphaera involved in
RT enhanced biological phosphorus removal.";
RL ISME J. 7:543-554(2013).
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCH80524.1}.
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DR EMBL; CAJB01000435; CCH80524.1; -; Genomic_DNA.
DR RefSeq; WP_048552618.1; NZ_HF570958.1.
DR AlphaFoldDB; A0A077M903; -.
DR STRING; 1194083.BN12_990010; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000035721; Unassembled WGS sequence.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000035721}.
FT DOMAIN 156..482
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 487 AA; 50554 MW; B491D9F4CA98E837 CRC64;
MNAPIRRLAT VVAALFAALL ISTTMIQFVF AKSINARPDN RRTLLSTFGV QRGQILADGK
AVAESVPSDD EYKWQRKYTQ AELYAHVTGY YSFLYGAGGG LEGSENDLLS GSSDKLFYQR
ISDLLTGKKP RGASLTTTID AAAQRAAEEG LGNQRGAAIA IDPRTGAILA MVSHPSYDPN
VLASHDIDAT VKAWRTLTTD KSQPMVNRTI AGNLYPPGST FKLVTAAAAL SSGKFTPSSV
LPGQAVLDLP GTTVGLPNDG HVPCSPTGKV TLTEALRVSC NPAFGQLGMD LGQDAVRAQA
AKFGVGDELA VPMRVTPSVF PTGLNEAQLA QSSIGQFDVR MTPLQVAMIS AAIANRGVVM
KPYLVKSAIV DSELSVVDRA QPERLSEAVT PEVANELKSM MIGVVQGGTG TAAQIPGVEV
AGKTGTAETA AGANPDAWFT GFAPANGTPK VAVAVIVEDG GNAGSEAAGG RVAGPIARDI
MKAVLGE
//
