ID A0A077Z2X8_TRITR Unreviewed; 2783 AA.
AC A0A077Z2X8;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=Fmp27 GFWDK and Apt1 and Zip domain containing pr otein {ECO:0000313|EMBL:CDW54842.1};
GN ORFNames=TTRE_0000311201 {ECO:0000313|EMBL:CDW54842.1};
OS Trichuris trichiura (Whipworm) (Trichocephalus trichiurus).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Trichinellida; Trichuridae; Trichuris.
OX NCBI_TaxID=36087 {ECO:0000313|EMBL:CDW54842.1};
RN [1] {ECO:0000313|EMBL:CDW54842.1}
RP NUCLEOTIDE SEQUENCE.
RA Aslett M.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CDW54842.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Foth B.J., Tsai I.J., Reid A.J., Bancroft A.J., Nichol S., Tracey A.,
RA Holroyd N., Cotton J.A., Stanley E.J., Zarowiecki M., Liu J.Z.,
RA Huckvale T., Cooper P.J., Grencis R.K., Berriman M.;
RT "The whipworm genome and dual-species transcriptomics of an intimate host-
RT pathogen interaction.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; HG805918; CDW54842.1; -; Genomic_DNA.
DR STRING; 36087.A0A077Z2X8; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR019443; BLTP2/FMP27/Hobbit_C.
DR InterPro; IPR048872; BLTP2_RBG6.
DR InterPro; IPR019441; FMP27/BLTP2/Hobbit_GFWDK_RBG.
DR InterPro; IPR045167; Hobbit.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR15678; ANTIGEN MLAA-22-RELATED; 1.
DR PANTHER; PTHR15678:SF6; PROTEIN KIAA0100; 1.
DR Pfam; PF21675; BLTP2_RBG-6; 1.
DR Pfam; PF10351; FMP27-BLTP2_C; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR Pfam; PF02535; Zip; 1.
DR SMART; SM01214; Fmp27_GFWDK; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 29..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 326..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2521..2542
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2637..2655
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1314..1486
FT /note="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01214"
SQ SEQUENCE 2783 AA; 317434 MW; 3D37CCD64CF274CD CRC64;
MIRLLGLSYP NDNNGQDATS FWSIAHVKLL LIVCLLVVTL GSSLFPLLFR RIVSNAQSLR
IRQQVVTIFS LLSCFGGGVF LGTSLLDLLP DTREELLEAA DSSSYSFRNF PLAEFFTAIG
FSFILCIEQL AIHAKWTCGR RASVASSNQS NCGTAGASTC EGKPLLNESH RQPSYSSVTN
EEDVHEDPMT HSWLRAIILV LTLSIHALFE GLAMGLIGQY TTAFQIFAAL CIHRSLVAFS
LGLRLISFKD VSTCTVILFC TAFAAVGSLG GFIGIVLSEA LRSKLAHFIT GSLQGIACGT
FLYIVTFEIL PHELSTSTAH LLPVKLIFFL AGLGTIAFVL YYASVFFYGR LKVKITALLH
CVLRKMLRCE NVACGNFGFV SLSRLSIRYE GVSLVWQPHL LLQLYSRALS GNRPRLDTYV
VLCLNYVRVE SSLCDLRLHR NSRTRWSNPW LKSIICQCMK VVAFEVGSVN VALLDTFPGF
LLHATFEDIS LYSAPLTWNL WQLSCYLKLF NLKVLERLSA ESPSVNYLNI VNRLTLTLQL
STDDLRLKLV QLECYSPVAS FSSGFANVVC RQMEKRLIRA KFGHDGSVSW TRLLSSTSFE
LMISRPLVRF SISGQRNLQL MLSHLSVSAD GSLPKTIQVQ LSDLLLVESK LDMVSLATRR
LVCNIKLDPS CHVRSSMELF VDCARVCIDY EDFLSCLTCV APLLSGYTKM NQSKGALLGC
MSVRLVYSFV QVGLPDDLLL TFQFACIYFV KKSPIKSEFG LHTFGWHIGA AKSEPATADF
KNKSATHKWG WSVIDGACVF KLHHLFGCTF VQAYLRRLDL ECRIEWIRMA CRLFKAIYKA
VEKPTESACS PPTRAKKYAF KLNVDEISIF IPLFQFEACC LFRFTSSSTA YTPELSTFFI
ELAECYSFSI TTSTEDLKMS MLQEERLNRS YIEAVSISCW RTDYWNVKVS VKKSSVLYWS
PSLHMLLYKT FSTFAKLSML LSQRKKSAKA ASRDGGSAKR AFWKSSKSII SFNSTLQVNF
RLPEDHNLEF KLPEAKLSLK FGNPSIEANS LVISCDSHPV FNLTGVCIEK VPSYPMFNVL
RQYIKVLMSP RNSCWIWSIK TLAIVFPYGY HFNAIHEQII NAWKWVKSLR SSGRLLDVPV
MWSDWHIKIG VTNVSDPNCS YCNTVSIEIC DDPFEVKLRD NYTLMVDEYF EAENRAAILR
SRIEEQCLAG SLTAQPDLND LFACLSKRSS SIYIQRSQKL YKGLPSRTSL FRCSFEAMDL
KVFADINFLG ETRLCQQIRS MDPSSPWPDQ PHFQTLWCRY VDLNFNEMFA QMRDYPLPYM
DIKDGRVAGR FAGCEMRGSE RSKFSRLFAK FTSSLIVARF RTVNFALGHK FGFSTLERHI
GVLKYFYDFS SAVVLTLSPV SYSITIYGDV IFILEFKTFR WSYGPCWEPC LAMINSCLAL
IRRRSLDPSP PLPFWDKARL LFHGRLRLLS NKLVLALLAS SDPYNDTEQL EWTWEKLLFE
WKSGKYYDIK FPRHHLCLIC RKRAAEIVKV RRLLSISFPQ FETQVTFFVC SQFRVESLFL
FSLRFDWSCI GNPYNHNAVS LCAPDKLPDR SADQRHDSYG AFRSQHLNLT FIIDVHEKRE
CTDSLRVLLY SNTFRWLVRL RDTVSAINRP VKRGSLYSNM RTPKSQLSRH YKKLNISISL
PKFLVTYWPS FTSDRGVHFT CSALQLSSAH ELHLEDFTSS ELLYRRKRTK IRTTFLNARM
SHVDCYLLGN CPDHCVDEKK SFFVGIDRLT YCRDLIDFNG VPVFPILLLA IEDVTVHHVV
VRNVKAIWTT FNRDIALHIY DNIEKGKIIR RNLSTDALKL VIDNESDKAL NAVEQKKQDA
VAKPFCQTED GSIKLLQKLI EEANTKSVAY CEEVRASDSD RKRHDLTGIQ LCQEDDVLFS
KWQSMLLLHF TFLPLRTPLI IAVELISMQV ALKGCDTTGY ILCTAAHGRI VNKIHQPIWR
ANQLLGKSTW VTRFTGMQYF ATVNPGDKMS KTSSTSTESF RANSDVSEFK FLDIALLNSD
AESPGRLTNS ARQAKRESKL VCKAERSSLP SVSPTDRVAA FAGNECPDHQ WETNDGDFCY
IKTNSLPFDS QWLSSLDQVQ WLGKDLIEES FSSDRLSDVV TSVINEGDSA GGVIPESSLR
DASLQRVISR CSCELMVCCF TENFEPSELG ILHVSARECD GITECDPDDC VTLIHPKLDI
HTSYDQYSMI LDVVNNLILY VDPNKKKSAE NLLKFRFKMQ LQSLDDLRPY ILSLQNEVRI
LWAQNRDIEL AMYHMHPLLK DHPELVPSYL ELSKDLEESK ANLSLKNEDL HIAIRELFCF
ADLKSAVARR FEVSIEEAQW CLTEANGQLG LAQLQLENFL YTKVSRINDS GEHMFELNSL
KIINLLPNSP FMEVLQMQES HSATHKPAVL VVCRELAPGI ILCGLTHCLA VLRFAVGGIT
VLEHLEVSVR PMIVQMTYIF FHTMMKFFFP DRNIETAEES VRNETGSVTH RKKKKHRRSK
VRFSSFYFVS SFAHISFQFA IIRKSMMPKK RKLTKEPGNY IDLMKLRAMK NILFMNVRVN
EVPIVVTYKG ASNGYIDNFK NFELTFPLIE YHNQNWTWLD LAVGIKAKSL RVLLKQVLLV
ASIFFCWNCL SVYLLKVVRR KLMKPRLADF FGGRKAESYQ ELRDEDKKRM ILALTTCTVR
AIYFCKSFDT FCHLVPTPNV LLERRYDYAD LTEQKVLLVL PANTFVKGEA TVDRFEQLLR
ENIRSVFLSF ESFYMTEDTS RDG
//
