ID A0A078M5E1_9STAP Unreviewed; 443 AA.
AC A0A078M5E1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Guanine/hypoxanthine permease PbuG {ECO:0000313|EMBL:CEA01449.1};
GN Name=pbuG {ECO:0000313|EMBL:CEA01449.1};
GN ORFNames=BN1048_01375 {ECO:0000313|EMBL:CEA01449.1};
OS Jeotgalicoccus saudimassiliensis.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Jeotgalicoccus.
OX NCBI_TaxID=1461582 {ECO:0000313|EMBL:CEA01449.1, ECO:0000313|Proteomes:UP000044136};
RN [1] {ECO:0000313|EMBL:CEA01449.1, ECO:0000313|Proteomes:UP000044136}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13MG44_air {ECO:0000313|EMBL:CEA01449.1,
RC ECO:0000313|Proteomes:UP000044136};
RA Urmite Genomes Urmite Genomes;
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|PIRNR:PIRNR005353};
CC Multi-pass membrane protein {ECO:0000256|PIRNR:PIRNR005353}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697,
CC ECO:0000256|PIRNR:PIRNR005353}.
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DR EMBL; CCSE01000001; CEA01449.1; -; Genomic_DNA.
DR RefSeq; WP_035809725.1; NZ_CCSE01000001.1.
DR AlphaFoldDB; A0A078M5E1; -.
DR STRING; 1461582.BN1048_01375; -.
DR eggNOG; COG2252; Bacteria.
DR HOGENOM; CLU_024508_0_1_9; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000044136; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR026033; Azg-like_bact_archaea.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337:SF11; GUANINE_HYPOXANTHINE PERMEASE PBUG; 1.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PIRSF; PIRSF005353; PbuG; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PIRNR:PIRNR005353};
KW Reference proteome {ECO:0000313|Proteomes:UP000044136};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|PIRNR:PIRNR005353};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005353}.
FT TRANSMEM 21..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..77
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 89..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..131
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..163
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 175..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..350
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 357..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 423..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 443 AA; 46778 MW; 3012BB12F653A9E9 CRC64;
MKKFFGFDEL DTNFKREVIG GLTTFLSMAY ILAVNPSILS LQGIEGVPDD MKMDINAVFV
ATCLAAFVGC LFMGIIAKYP IALAPGMGLN AFFAFTVVLT MGIPWQTALT GVLFSGVVFV
ILTLTGLREY IINAIPMEMK MAVSAGIGFF ITFVGLQSSG IIAGDEATLI SLGNVQSGGV
LLTFAGLVIT VILMTKKVPA AIFVGMIATA VLGIVTGIVP MPSAVVGSVP SVAPTFGAAL
EGLMDFEAIF NVQFMIVVLT FLFVDFFDTA GTLVGVASQA NLIKDNKLPR ASKALLADAF
ATITGAIFGT STTTSYVEST AGVAAGARSG FASVVTGVLF LAAIFFSPLI VTFTSEVTAP
ALIIVGILMA SNLSKITWGR FEVAVPAFLT VFMMPLTYSI ATGIAIGFIF YPITMLMAGK
RKEVHPIMYG LFIVFILYFL FIN
//
