ID   A0A080M118_9PROT        Unreviewed;       228 AA.
AC   A0A080M118;
DT   29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Clan AA aspartic protease {ECO:0000313|EMBL:KFB74947.1};
GN   ORFNames=AW06_004049 {ECO:0000313|EMBL:KFB74947.1};
OS   Candidatus Accumulibacter cognatus.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX   NCBI_TaxID=2954383 {ECO:0000313|EMBL:KFB74947.1, ECO:0000313|Proteomes:UP000021315};
RN   [1] {ECO:0000313|EMBL:KFB74947.1, ECO:0000313|Proteomes:UP000021315}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SK-02 {ECO:0000313|Proteomes:UP000021315};
RA   Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT   "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT   clades.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFB74947.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JDST02000112; KFB74947.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A080M118; -.
DR   STRING; 1453999.AW06_004049; -.
DR   Proteomes; UP000021315; Unassembled WGS sequence.
DR   GO; GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd05483; retropepsin_like_bacteria; 1.
DR   Gene3D; 2.40.70.10; Acid Proteases; 1.
DR   InterPro; IPR001969; Aspartic_peptidase_AS.
DR   InterPro; IPR011969; Clan_AA_Asp_peptidase_C.
DR   InterPro; IPR021109; Peptidase_aspartic_dom_sf.
DR   InterPro; IPR034122; Retropepsin-like_bacterial.
DR   NCBIfam; TIGR02281; clan_AA_DTGA; 1.
DR   Pfam; PF13975; gag-asp_proteas; 1.
DR   SUPFAM; SSF50630; Acid proteases; 1.
DR   PROSITE; PS00141; ASP_PROTEASE; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:KFB74947.1};
KW   Protease {ECO:0000313|EMBL:KFB74947.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000021315};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..36
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           37..228
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001751003"
SQ   SEQUENCE   228 AA;  23924 MW;  22A3B141A10873D3 CRC64;
     MVKRRVGNGG HWRCGWMAIR QVLCLSSCLL CGSALAVDVG LAGVFPGKAL LTINGGAPRT
     VAVGTKTDEG IKVLSVDNDT ATIETDGKKR ILRVGQNVAS QPAGEGGGKA VLTADGSGHF
     LTTGNINGTT VRFLVDTGAT MISLGAGDAR RIGIDASKGQ RGVTSTANGP ALVIHIKLDT
     VRVGEIVLNN VDALVHQQDL PFALLGMSFL NRMEMQRDGQ TMTLRKRY
//