ID A0A081CHK1_PSEA2 Unreviewed; 1315 AA.
AC A0A081CHK1;
DT 29-OCT-2014, integrated into UniProtKB/TrEMBL.
DT 29-OCT-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=18S rRNA biogenesis protein {ECO:0000313|EMBL:GAK66147.1};
GN ORFNames=PAN0_011d4369 {ECO:0000313|EMBL:GAK66147.1};
OS Pseudozyma antarctica (Yeast) (Candida antarctica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Moesziomyces.
OX NCBI_TaxID=84753 {ECO:0000313|EMBL:GAK66147.1};
RN [1] {ECO:0000313|EMBL:GAK66147.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=JCM 10317 {ECO:0000313|EMBL:GAK66147.1};
RA Morita T., Saika A., Koike H.;
RT "Draft genome sequence of the yeast Pseudozyma antarctica JCM 10317 known
RT as a producer of lipase B which used in a wide range of industrial
RT applications.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the RNA 3'-terminal cyclase family. Type 2
CC subfamily. {ECO:0000256|ARBA:ARBA00007089}.
CC -!- SIMILARITY: Belongs to the biotin--protein ligase family.
CC {ECO:0000256|ARBA:ARBA00009934}.
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DR EMBL; DF830078; GAK66147.1; -; Genomic_DNA.
DR RefSeq; XP_014655825.1; XM_014800339.1.
DR GeneID; 26305204; -.
DR HOGENOM; CLU_006150_1_0_1; -.
DR OrthoDB; 317678at2759; -.
DR Proteomes; UP000053758; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:InterPro.
DR GO; GO:0004077; F:biotin-[acetyl-CoA-carboxylase] ligase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd16442; BPL; 1.
DR CDD; cd03144; GATase1_ScBLP_like; 1.
DR CDD; cd00875; RNA_Cyclase_Class_I; 1.
DR Gene3D; 3.65.10.20; RNA 3'-terminal phosphate cyclase domain; 1.
DR Gene3D; 3.30.360.20; RNA 3'-terminal phosphate cyclase, insert domain; 1.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR019197; Biotin-prot_ligase_N.
DR InterPro; IPR004408; Biotin_CoA_COase_ligase.
DR InterPro; IPR004143; BPL_LPL_catalytic.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR013791; RNA3'-term_phos_cycl_insert.
DR InterPro; IPR023797; RNA3'_phos_cyclase_dom.
DR InterPro; IPR037136; RNA3'_phos_cyclase_dom_sf.
DR InterPro; IPR000228; RNA3'_term_phos_cyc.
DR InterPro; IPR016443; RNA3'_term_phos_cyc_type_2.
DR InterPro; IPR020719; RNA3'_term_phos_cycl-like_CS.
DR InterPro; IPR013792; RNA3'P_cycl/enolpyr_Trfase_a/b.
DR InterPro; IPR036553; RPTC_insert.
DR NCBIfam; TIGR03400; 18S_RNA_Rcl1p; 1.
DR PANTHER; PTHR11096; RNA 3' TERMINAL PHOSPHATE CYCLASE; 1.
DR PANTHER; PTHR11096:SF1; RNA 3'-TERMINAL PHOSPHATE CYCLASE-LIKE PROTEIN; 1.
DR Pfam; PF03099; BPL_LplA_LipB; 1.
DR Pfam; PF09825; BPL_N; 1.
DR Pfam; PF01137; RTC; 1.
DR Pfam; PF05189; RTC_insert; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR SUPFAM; SSF55205; EPT/RTPC-like; 1.
DR PROSITE; PS51733; BPL_LPL_CATALYTIC; 1.
DR PROSITE; PS01287; RTC; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053758};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517}.
FT DOMAIN 978..1209
FT /note="BPL/LPL catalytic"
FT /evidence="ECO:0000259|PROSITE:PS51733"
FT REGION 360..381
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..557
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..557
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1315 AA; 142175 MW; 5BAB60F308D1E8C2 CRC64;
MAASGSSSAT TEKSRLLRFT GHRNFRQRLV LALVSQRPVR IDGIRPDSSS PGIRDFEANF
LRLLEKVTNG SHVEISYTGT SVLLKPGIIA GGKVVHDCAL TRGIGYWLEW MVVLAPFAKK
ELHLTLKGVT NMEGDLGVDT IRTVTLPHLS LFLPLDSVST LASSLELRIA KRGSAPGGGG
EVHFRCPIIK NLSTINFTAP GRIKKIRGIA TSTRVSPQMA NRLIDAARGV LGCYIPDLYL
FADVYRGEDS GKSPGFAITL LATSTTGAIY SAEAVSKIQD PGLPEDLAQD AARMLLTEIA
GRGCIDRSHQ PMALLLMALS PQDVARCTMA HPTANAIQMM RDLKHALGVS FKIAHADASA
PDASNDAESE ASDSDDNDQD TMLKSLKKPA QFAVSCVGIN FAGFRKCTPA PELDRESGPE
ECSVNLVGRV VTAVARTGLF PAVLRPAAQA RPRRIASAFV RSVSSMSDVL VYSGPGVSTS
ALHHTLKTLR LLLTTYDVKT VDARTLALDP WQKGTALVLL PGGRDLPYVA ELAKPFRRDD
SQSTPSSRGG GERTASNEVR NFVQAGGNFM GICAGAYYAS SHCSFELGTS MQVDGERPFL
RFYPGTCQGT VYAGFVYESD KGARIVDLDR TLADGKVDQW RCHYNGGGAF MDADAYADQG
VEVLARYART QPDELRLDME LNDSSAARRP DYAGQAAVVL ASVGAGKALL FGTHPEFPLL
PTSTPVLLAE NSQALAREHI DRAEHERQLR VHEQRRLHWM HELFTNRLGL RSELPQWAMA
AAVSDKTASA PTGTAVDTAE PKLLPIFLSA VGRDSDYTLD AIATKLAAET STTPPAHLAG
FDACEALKAA RIASVKDSND AMYFARADAE SIKEAQALCT SADYDAFSKP ILPAITPAEG
EEAGSKPDKE VDLDAVPKYI LVCKEQKPSR DVLPYWDMAA YETHLEHFRE LNAQRAQAGE
PDHWTSWRAP FDPFNPFGSS SGVVAEHRFG TPTLYTQMVT STQTILDKNF RLLAALPVGT
TFFATQQMSG RGRGGNRWIS PKGCLQFSAV FRVPVSMASK TVFLQYLSGL AVVEGIRLAL
GPGDAARAVA DKVRIKWPND IYAEIPTADE EGHGGARTKT ATFELGGKRY AKLGGILVNS
QFSGGNEFVL VSGCGVNCLN ARPTTSVSDL VTMHNDRAAN EADKLEVVSQ EKLAGAILST
FDSIWKVFLQ HGGDFRPFVS RYRQVWLHSD QETTLTQDAI RSDATAHTEG DEGVRIVGIS
SDYGLLQAVP RTSSIYAKDA KAWGSTQDAQ ANGIVQLQPD GNSFDMLQNL VKRKV
//
